Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n = 17,706)

Microstructural integrity of white matter moderates an association between childhood adversity and adult trait anger

(2019) M. Justin Kim et al.   AGGRESSIVE BEHAVIOR

The use of polygenic risk scores to identify phenotypes associated with genetic risk of bipolar disorder and depression: A systematic review

(2018) Sumit Mistry et al.   JOURNAL OF AFFECTIVE DISORDERS

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

(2018) Mats Nagel et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank

(2018) Fidel Alfaro-Almagro et al.   NEUROIMAGE

Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia

(2018) Loes C.A. Rutten-Jacobs et al.   STROKE

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

(2018) Gail Davies et al.   Nature Communications

Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts

(2018) Sandra Sanchez-Roige et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genome-wide association studies of brain imaging phenotypes in UK Biobank

(2018) Lloyd T. Elliott et al.   NATURE

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group

(2017) S Kelly et al.   MOLECULAR PSYCHIATRY

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium

(2017) J W Trampush et al.   MOLECULAR PSYCHIATRY

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

(2017) Michelle Luciano et al.   NATURE GENETICS

Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia

(2017) Zhiqiang Li et al.   NATURE GENETICS

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

(2017) Diana Chang et al.   NATURE GENETICS

Genetic architecture: the shape of the genetic contribution to human traits and disease

(2017) Nicholas J. Timpson et al.   NATURE REVIEWS GENETICS

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets

(2017) Max Lam et al.   Cell Reports

Diffusion MRI of white matter microstructure development in childhood and adolescence: Methods, challenges and progress

(2017) Christian K. Tamnes et al.   Developmental Cognitive Neuroscience

Estimating the Heritability of Structural and Functional Brain Connectivity in Families Affected by Attention-Deficit/Hyperactivity Disorder

(2017) Gustavo Sudre et al.   JAMA Psychiatry

Heritability of white matter microstructure in late middle age: A twin study of tract-based fractional anisotropy and absolute diffusivity indices

(2016) Eero Vuoksimaa et al.   HUMAN BRAIN MAPPING

Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

(2016) Aysu Okbay et al.   NATURE GENETICS

Gene expression elucidates functional impact of polygenic risk for schizophrenia

(2016) Menachem Fromer et al.   NATURE NEUROSCIENCE

Dissecting the genetics of complex traits using summary association statistics

(2016) Bogdan Pasaniuc et al.   NATURE REVIEWS GENETICS

Common and heritable components of white matter microstructure predict cognitive function at 1 and 2 y

(2016) Seung Jae Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ageing and brain white matter structure in 3,513 UK Biobank participants

(2016) Simon R. Cox et al.   Nature Communications

A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome

(2016) Anthony D. Schmitt et al.   Cell Reports

Coupled Changes in Brain White Matter Microstructure and Fluid Intelligence in Later Life

(2015) S. J. Ritchie et al.   JOURNAL OF NEUROSCIENCE

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

(2015) T-K Clarke et al.   MOLECULAR PSYCHIATRY

A novel Alzheimer disease locus located near the gene encoding tau protein

(2015) G Jun et al.   MOLECULAR PSYCHIATRY

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

(2015) Po-Ru Loh et al.   NATURE GENETICS

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

Quantitative tract-based white matter heritability in twin neonates

(2015) Seung Jae Lee et al.   NEUROIMAGE

Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data

(2015) Peter Kochunov et al.   NEUROIMAGE

Genetic underpinnings of white matter ‘connectivity’: Heritability, risk, and heterogeneity in schizophrenia

(2015) Aristotle N. Voineskos   SCHIZOPHRENIA RESEARCH

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

(2015) Naomi Kouri et al.   Nature Communications

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Genetic variability in the regulation of gene expression in ten regions of the human brain

(2014) Adaikalavan Ramasamy et al.   NATURE NEUROSCIENCE

Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling

(2014) Peter Kochunov et al.   NEUROIMAGE

Methodological considerations on tract-based spatial statistics (TBSS)

(2014) Michael Bach et al.   NEUROIMAGE

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA–DTI working group

(2013) Neda Jahanshad et al.   NEUROIMAGE

Neuroimaging of the Philadelphia Neurodevelopmental Cohort

(2013) Theodore D. Satterthwaite et al.   NEUROIMAGE

Effectiveness of regional DTI measures in distinguishing Alzheimer's disease, MCI, and normal aging

(2013) Talia M. Nir et al.   NeuroImage-Clinical

Genetics of ageing-related changes in brain white matter integrity – A review

(2012) Sri C. Kanchibhotla et al.   AGEING RESEARCH REVIEWS

Brain-wide white matter tract integrity is associated with information processing speed and general intelligence

(2012) L Penke et al.   MOLECULAR PSYCHIATRY

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder

(2012) S E Bergen et al.   MOLECULAR PSYCHIATRY

White matter integrity, fiber count, and other fallacies: The do's and don'ts of diffusion MRI

(2012) Derek K. Jones et al.   NEUROIMAGE

Genome partitioning of genetic variation for complex traits using common SNPs

(2011) Jian Yang et al.   NATURE GENETICS

White matter lesions in Parkinson disease

(2011) Nicolaas I. Bohnen et al.   Nature Reviews Neurology

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Intellectual abilities and white matter microstructure in development: A diffusion tensor imaging study

(2010) Christian K. Tamnes et al.   HUMAN BRAIN MAPPING

Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study

(2010) Patricia L. Kramer et al.   NEUROBIOLOGY OF AGING

Heritability of DTI and MTR in nine-year-old children

(2010) Rachel M. Brouwer et al.   NEUROIMAGE

BDNF gene effects on brain circuitry replicated in 455 twins

(2010) Ming-Chang Chiang et al.   NEUROIMAGE

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

(2009) Shaun M. Purcell et al.   NATURE