Host Modulation and Treatment of Periodontal Disease

Efficacy of baricitinib on periodontal inflammation in patients with rheumatoid arthritis

(2020) Codrina Ancuța et al.   JOINT BONE SPINE

Omega‐3 PUFA and aspirin as adjuncts to periodontal debridement in patients with periodontitis and type 2 diabetes mellitus. Randomized clinical trial

(2020) Nidia C Castro dos Santos et al.   JOURNAL OF PERIODONTOLOGY

A systematic review and meta-analysis of clinical, immunological and microbiological shift in periodontitis after non-surgical periodontal therapy with adjunctive use of probiotics

(2020) Sze Nga Ho et al.   Journal of Evidence-Based Dental Practice

Shifting the paradigm from inhibitors of inflammation to resolvers of inflammation in periodontitis

(2020) Thomas E. Van Dyke   JOURNAL OF PERIODONTOLOGY

Complement split product C3c in saliva as biomarker for periodontitis and response to periodontal treatment

(2020) Maria Anastasia Grande et al.   JOURNAL OF PERIODONTAL RESEARCH

n-3 PUFA and inflammation: from membrane to nucleus and from bench to bedside

(2020) Philip C. Calder   PROCEEDINGS OF THE NUTRITION SOCIETY

Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

(2020) Panagiotis Skendros et al.   JOURNAL OF CLINICAL INVESTIGATION

Current understanding of periodontal disease pathogenesis and targets for host‐modulation therapy

(2020) George Hajishengallis et al.   PERIODONTOLOGY 2000

Bifidobacterium animalis subsp lactis HN019 presents antimicrobial potential against periodontopathogens and modulates the immunological response of oral mucosa in periodontitis patients

(2020) Marcos M. Invernici et al.   PLoS One

Comparing the Effects of Docosahexaenoic and Eicosapentaenoic Acids on Inflammation Markers Using Pairwise and Network Meta-Analyses of Randomized Controlled Trials

(2020) Cécile Vors et al.   Advances in Nutrition

Use of TNF Inhibitors in Rheumatoid Arthritis and Implications for the Periodontal Status: For the Benefit of Both?

(2020) Fatima Zamri et al.   Frontiers in Immunology

Maresin-1 and Resolvin E1 Promote Regenerative Properties of Periodontal Ligament Stem Cells Under Inflammatory Conditions

(2020) Emmanuel Albuquerque-Souza et al.   Frontiers in Immunology

Contribution of Statins towards Periodontal Treatment: A Review

(2019) Catherine Petit et al.   MEDIATORS OF INFLAMMATION

Effects of topical application of 1% sodium alendronate gel in the surgical treatment of periodontal intrabony defects: A 6‐month randomized controlled clinical trial

(2019) Bernardo Carvalho Dutra et al.   JOURNAL OF PERIODONTOLOGY

The pros, cons, and many unknowns of probiotics

(2019) Jotham Suez et al.   NATURE MEDICINE

Oral microbial dysbiosis linked to worsened periodontal condition in rheumatoid arthritis patients

(2019) Jôice Dias Corrêa et al.   Scientific Reports

A dual strain Lactobacilli reuteri probiotic improves the treatment of residual pockets: a randomized controlled‐clinical trial

(2019) Isabelle Laleman et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Annual alveolar bone loss in older adults taking oral bisphosphonate: a retrospective cohort study

(2019) Mohammad Helmi et al.   BMC Oral Health

Marine Omega‐3 Supplementation and Cardiovascular Disease: An Updated Meta‐Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants

(2019) Yang Hu et al.   Journal of the American Heart Association

Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses

(2019) Patricia R. Souza et al.   CIRCULATION RESEARCH

The adjunctive use of host modulators in non‐surgical periodontal therapy. A systematic review of randomized, placebo‐controlled clinical studies

(2019) N Donos et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Periodontal therapeutics: Current host‐modulation agents and future directions

(2019) Lorne M. Golub et al.   PERIODONTOLOGY 2000

Association of different immunosuppressive medications with periodontal condition in patients with rheumatoid arthritis - results from a cross-sectional study

(2018) Dirk Ziebolz et al.   JOURNAL OF PERIODONTOLOGY

Resolvin D2 Restrains Th1 Immunity and Prevents Alveolar Bone Loss in Murine Periodontitis

(2018) Gabriel Mizraji et al.   Frontiers in Immunology

Resolvin E1 Promotes Bone Preservation Under Inflammatory Conditions

(2018) Karim El Kholy et al.   Frontiers in Immunology

Effects of Bifidobacterium probiotic on the treatment of chronic periodontitis: A randomized clinical trial

(2018) Marcos M. Invernici et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Gingival Exudatome Dynamics Implicate Inhibition of the Alternative Complement Pathway in the Protective Action of the C3 Inhibitor Cp40 in Nonhuman Primate Periodontitis

(2018) Nagihan Bostanci et al.   JOURNAL OF PROTEOME RESEARCH

Effects of Conventional Synthetic Disease-Modifying Antirheumatic Drugs on Response to Periodontal Treatment in Patients with Rheumatoid Arthritis

(2018) Gyu-Un Jung et al.   Biomed Research International

Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation

(2018) Paul C. Norris et al.   Scientific Reports

Clinical and microbiological effects of the adjunctive use of probiotics in the treatment of gingivitis: A randomized controlled clinical trial

(2017) Eduardo Montero et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

The effect of local and systemic statin use as an adjunct to non-surgical and surgical periodontal therapy—A systematic review and meta-analysis

(2017) Kristina Bertl et al.   JOURNAL OF DENTISTRY

Statins in nonsurgical and surgical periodontal therapy. A systematic review and meta-analysis of preclinical in vivo trials

(2017) K. Bertl et al.   JOURNAL OF PERIODONTAL RESEARCH

Dietary supplementation with low-dose omega-3 fatty acids reduces salivary tumor necrosis factor-α levels in patients with chronic periodontitis: a randomized controlled clinical study

(2017) I. Keskiner et al.   JOURNAL OF PERIODONTAL RESEARCH

Mandibular Degree II Furcation Defects Treatment With Platelet-Rich Fibrin and 1% Alendronate Gel Combination: A Randomized Controlled Clinical Trial

(2017) Dharmendra Kanoriya et al.   JOURNAL OF PERIODONTOLOGY

1.2% Rosuvastatin and 1.2% Atorvastatin Gel Local Drug Delivery and Redelivery in the Treatment of Class II Furcation Defects: A Randomized Controlled Clinical Trial

(2017) Shruti Garg et al.   JOURNAL OF PERIODONTOLOGY

Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1

(2017) Niki M. Moutsopoulos et al.   NEW ENGLAND JOURNAL OF MEDICINE

Host modulation therapy with anti-inflammatory agents

(2017) Philip M. Preshaw   PERIODONTOLOGY 2000

Periodontitis in early and chronic rheumatoid arthritis: a prospective follow-up study in Finnish population

(2017) Leena Äyräväinen et al.   BMJ Open

Emerging Concepts in the Resolution of Periodontal Inflammation: A Role for Resolvin E1

(2017) Maria G. Balta et al.   Frontiers in Immunology

Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3

(2016) Tomoki Maekawa et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

1.2% Rosuvastatin Versus 1.2% Atorvastatin Gel Local Drug Delivery and Redelivery in Treatment of Intrabony Defects in Chronic Periodontitis: A Randomized Placebo-Controlled Clinical Trial

(2016) A.R. Pradeep et al.   JOURNAL OF PERIODONTOLOGY

Synergistic Approach Using Platelet-Rich Fibrin and 1% Alendronate for Intrabony Defect Treatment in Chronic Periodontitis: A Randomized Clinical Trial

(2016) Dharmendra Kanoriya et al.   JOURNAL OF PERIODONTOLOGY

Anti-B lymphocyte immunotherapy is associated with improvement of periodontal status in subjects with rheumatoid arthritis

(2015) Juliette Coat et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Modulation of the host response by probioticLactobacillus brevisCD2 in experimental gingivitis

(2015) J-K Lee et al.   ORAL DISEASES

Docosahexaenoic Acid and Periodontitis in Adults

(2014) A.Z. Naqvi et al.   JOURNAL OF DENTAL RESEARCH

Host Modulation in Rheumatoid Arthritis Patients with TNF Blockers Significantly Decreases Biochemical Parameters in Periodontitis

(2013) Kemal Üstün et al.   INFLAMMATION

The efficacy of host response modulation therapy (omega-3 plus low-dose aspirin) as an adjunctive treatment of chronic periodontitis (Clinical and biochemical study)

(2011) A. M. Elkhouli   JOURNAL OF PERIODONTAL RESEARCH

Clinical Efficacy of 1% Alendronate Gel as a Local Drug Delivery System in the Treatment of Chronic Periodontitis: A Randomized, Controlled Clinical Trial

(2011) Anuj Sharma et al.   JOURNAL OF PERIODONTOLOGY

Adjunctive Treatment of Chronic Periodontitis With Daily Dietary Supplementation With Omega-3 Fatty Acids and Low-Dose Aspirin

(2010) Hesham El-Sharkawy et al.   JOURNAL OF PERIODONTOLOGY

n-3 Fatty Acids and Periodontitis in US Adults

(2010) Asghar Z. Naqvi et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Periodontal Therapy Reduces the Severity of Active Rheumatoid Arthritis in Patients Treated With or Without Tumor Necrosis Factor Inhibitors

(2009) P. Ortiz et al.   JOURNAL OF PERIODONTOLOGY

Anti–TNF-α Immunotherapy Is Associated With Increased Gingival Inflammation Without Clinical Attachment Loss in Subjects With Rheumatoid Arthritis

(2008) Jacques-Olivier Pers et al.   JOURNAL OF PERIODONTOLOGY