Protein expression and secretion by filamentous fungi

Comparative genomics of the aconidial Aspergillus niger strain LDM3 predicts genes associated with its high protein secretion capacity

(2020) Yu-Fei Sui et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Quantitative proteome profiling reveals cellobiose-dependent protein processing and export pathways for the lignocellulolytic responses in Neurospora crassa

(2020) Dan Liu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Novel Factor Essential for Unconventional Secretion of Chitinase Cts1

(2020) Michèle Reindl et al.   Frontiers in Microbiology

A new approach to Cas9-based genome editing in Aspergillus niger that is precise, efficient and selectable

(2019) Laure M. C. Leynaud-Kieffer et al.   PLoS One

Harnessing the knowledge of protein secretion for enhanced protein production in filamentous fungi

(2019) Xianhua Sun et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

A Potential Lock-Type Mechanism for Unconventional Secretion in Fungi

(2019) Michèle Reindl et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories

(2019) Timothy C. Cairns et al.   Biotechnology for Biofuels

Editorial: Advances in the Regulation and Production of Fungal Enzymes by Transcriptomics, Proteomics and Recombinant Strains Design

(2019) André Damasio et al.   Frontiers in Bioengineering and Biotechnology

Functional Genomics of Aspergillus oryzae: Strategies and Progress

(2019) He et al.   Microorganisms

CRISPR-Cas9 genome editing approaches in filamentous fungi and oomycetes

(2019) Mariana Schuster et al.   FUNGAL GENETICS AND BIOLOGY

Transcription Factor Atf1 Regulates Expression of Cellulase and Xylanase Genes during Solid-State Fermentation of Ascomycetes

(2019) Shuai Zhao et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Forward genetics screen coupled with whole-genome resequencing identifies novel gene targets for improving heterologous enzyme production in Aspergillus niger

(2018) Morgann C. Reilly et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Inducible promoters and functional genomic approaches for the genetic engineering of filamentous fungi

(2018) Janina Kluge et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The GlaA signal peptide substantially increases the expression and secretion of α-galactosidase in Aspergillus niger

(2018) Yue Xu et al.   BIOTECHNOLOGY LETTERS

Endoplasmic Reticulum Stress signalling - from basic mechanisms to clinical applications

(2018) Aitor Almanza et al.   FEBS Journal

Construction of an improved Aspergillus niger platform for enhanced glucoamylase secretion

(2018) Markus R. M. Fiedler et al.   Microbial Cell Factories

Genetic dissection of the secretory route followed by a fungal extracellular glycosyl hydrolase

(2018) Miguel Hernández-González et al.   MOLECULAR MICROBIOLOGY

A universal gene expression system for fungi

(2018) Anssi Rantasalo et al.   NUCLEIC ACIDS RESEARCH

Comparative systems analysis of the secretome of the opportunistic pathogen Aspergillus fumigatus and other Aspergillus species

(2018) R. P. Vivek-Ananth et al.   Scientific Reports

Conditional Expression of the Small GTPase ArfA Impacts Secretion, Morphology, Growth, and Actin Ring Position in Aspergillus niger

(2018) Markus R. M. Fiedler et al.   Frontiers in Microbiology

Protein profile in Aspergillus nidulans recombinant strains overproducing heterologous enzymes

(2018) Mariane Paludetti Zubieta et al.   Microbial Biotechnology

Protein hyperproduction in fungi by design

(2018) Scott E. Baker   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Endoplasmic Reticulum redox pathways: in sickness and in health

(2018) Adam M. Benham   FEBS Journal

Evaluation of Unconventional Protein Secretion by Saccharomyces cerevisiae and other Fungi

(2018) Natsuko Miura et al.   Cells

FlbA-Regulated Gene rpnR Is Involved in Stress Resistance and Impacts Protein Secretion when Aspergillus niger Is Grown on Xylose

(2018) David Aerts et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri

(2018) Tammi C. Vesth et al.   NATURE GENETICS

Overexpressing key component genes of the secretion pathway for enhanced secretion of an Aspergillus niger glucose oxidase in Trichoderma reesei

(2017) Yilan Wu et al.   ENZYME AND MICROBIAL TECHNOLOGY

Pathways of Unconventional Protein Secretion

(2017) Catherine Rabouille   TRENDS IN CELL BIOLOGY

Functional distinction of hyphal compartments

(2017) Martin Tegelaar et al.   Scientific Reports

Comparative genomics and transcriptome analysis of Aspergillus niger and metabolic engineering for citrate production

(2017) Xian Yin et al.   Scientific Reports

A benzoate-activated promoter from Aspergillus niger and regulation of its activity

(2016) Mauricio S. Antunes et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An Evolutionarily Conserved Transcriptional Activator-Repressor Module Controls Expression of Genes for D-Galacturonic Acid Utilization in Aspergillus niger

(2016) Jing Niu et al.   GENETICS

Highly active promoters and native secretion signals for protein production during extremely low growth rates in Aspergillus niger

(2016) Franziska Wanka et al.   Microbial Cell Factories

An Evolutionarily Conserved Transcriptional Activator-Repressor Module Controls Expression of Genes for D-Galacturonic Acid Utilization in Aspergillus niger

(2016) Jing Niu et al.   GENETICS

Autophagy is dispensable to overcome ER stress in the filamentous fungusAspergillus niger

(2016) Anne-Marie Burggraaf et al.   MicrobiologyOpen

Approaches to understanding protein hypersecretion in fungi

(2016) Morgann C. Reilly et al.   Fungal Biology Reviews

Secretion of small proteins is species-specific withinAspergillussp

(2016) Nicolas Valette et al.   Microbial Biotechnology

Closely related fungi employ diverse enzymatic strategies to degrade plant biomass

(2015) Isabelle Benoit et al.   Biotechnology for Biofuels

Construction of a Shuttle Vector for Heterologous Expression of a Novel Fungal ��-Amylase Gene in Aspergillus oryzae

(2015) Yanchen Yin et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Heterologous expression of cellobiohydrolases in filamentous fungi – An update on the current challenges, achievements and perspectives

(2015) Marta Zoglowek et al.   PROCESS BIOCHEMISTRY

Bringing functions together with fusion enzymes—from nature’s inventions to biotechnological applications

(2014) Skander Elleuche   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Unfolded protein response in filamentous fungi—implications in biotechnology

(2014) Kai Heimel   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Challenges and advances in the heterologous expression of cellulolytic enzymes: a review

(2014) Camilla Lambertz et al.   Biotechnology for Biofuels

Comparison of intracellular and secretion-based strategies for production of human α-galactosidase A in the filamentous fungus Trichoderma reesei

(2014) Wesley Smith et al.   BMC BIOTECHNOLOGY

The Transcription Factor Titration Effect Dictates Level of Gene Expression

(2014) Robert C. Brewster et al.   CELL

Vesicle trafficking, organelle functions, and unconventional secretion in fungal physiology and pathogenicity

(2014) Jun-ya Shoji et al.   CURRENT OPINION IN MICROBIOLOGY

Fusion protein linkers: Property, design and functionality

(2012) Xiaoying Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Expression and secretion of Aspergillus fumigatus proteases are regulated in response to different protein substrates

(2012) Edward Farnell et al.   Fungal Biology

Construction of a cellulase hyper-expression system in Trichoderma reesei by promoter and enzyme engineering

(2012) Gen Zou et al.   Microbial Cell Factories

Fungal Gene Expression on Demand: an Inducible, Tunable, and Metabolism-Independent Expression System for Aspergillus niger

(2011) Vera Meyer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Production of recombinant proteins by filamentous fungi

(2011) Owen P. Ward   BIOTECHNOLOGY ADVANCES

Utility of Aspergillus niger citrate synthase promoter for heterologous expression

(2011) Kashyap Dave et al.   JOURNAL OF BIOTECHNOLOGY

Septum-directed secretion in the filamentous fungus Aspergillus oryzae

(2011) Yugo Hayakawa et al.   MOLECULAR MICROBIOLOGY

Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger

(2010) Neuza D. S. P. Carvalho et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Expression and export: recombinant protein production systems for Aspergillus

(2010) André Fleißner et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Expanding the ku70 toolbox for filamentous fungi: establishment of complementation vectors and recipient strains for advanced gene analyses

(2010) Neuza D. S. P. Carvalho et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An inventory of the Aspergillus niger secretome by combining in silico predictions with shotgun proteomics data

(2010) Machtelt Braaksma et al.   BMC GENOMICS

In vivo imaging of endoplasmic reticulum and distribution of mutant α-amylase in Aspergillus oryzae

(2010) Shinya Kimura et al.   FUNGAL GENETICS AND BIOLOGY

The intra- and extracellular proteome of Aspergillus niger growing on defined medium with xylose or maltose as carbon substrate

(2010) Xin Lu et al.   Microbial Cell Factories

Peroxicretion: a novel secretion pathway in the eukaryotic cell

(2009) Cees MJ Sagt et al.   BMC BIOTECHNOLOGY

Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway

(2009) Thomas R Jørgensen et al.   BMC GENOMICS

Genomics of protein folding in the endoplasmic reticulum, secretion stress and glycosylation in the aspergilli

(2009) Steven Geysens et al.   FUNGAL GENETICS AND BIOLOGY

Analytical and computational approaches to define the Aspergillus niger secretome

(2009) Adrian Tsang et al.   FUNGAL GENETICS AND BIOLOGY

Approaches for refining heterologous protein production in filamentous fungi

(2009) Ruchika Sharma et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Genetic engineering of filamentous fungi — Progress, obstacles and future trends

(2008) Vera Meyer   BIOTECHNOLOGY ADVANCES

Developing Aspergillus as a host for heterologous expression

(2008) David Lubertozzi et al.   BIOTECHNOLOGY ADVANCES