Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories

Systems metabolic engineering for citric acid production by Aspergillus niger in the post-genomic era

(2019) Zhenyu Tong et al.   Microbial Cell Factories

An X-ray microtomography-based method for detailed analysis of the three-dimensional morphology of fungal pellets

(2019) Stefan Schmideder et al.   BIOTECHNOLOGY AND BIOENGINEERING

The filamentous fungal pellet—relationship between morphology and productivity

(2018) Lukas Veiter et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Mushroom cultivation in the circular economy

(2018) Daniel Grimm et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Morphological regulation of Aspergillus niger to improve citric acid production by chsC gene silencing

(2018) Xiaowen Sun et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Construction of an improved Aspergillus niger platform for enhanced glucoamylase secretion

(2018) Markus R. M. Fiedler et al.   Microbial Cell Factories

Fungal Morphogenesis, from the Polarized Growth of Hyphae to Complex Reproduction and Infection Structures

(2018) Meritxell Riquelme et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

5S rRNA Promoter for Guide RNA Expression Enabled Highly Efficient CRISPR/Cas9 Genome Editing in Aspergillus niger

(2018) Xiaomei Zheng et al.   ACS Synthetic Biology

Conditional Expression of the Small GTPase ArfA Impacts Secretion, Morphology, Growth, and Actin Ring Position in Aspergillus niger

(2018) Markus R. M. Fiedler et al.   Frontiers in Microbiology

Rocking Aspergillus: morphology-controlled cultivation of Aspergillus niger in a wave-mixed bioreactor for the production of secondary metabolites

(2018) Tutku Kurt et al.   Microbial Cell Factories

Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast

(2018) Jingchuan Luo et al.   NATURE

Creating a functional single-chromosome yeast

(2018) Yangyang Shao et al.   NATURE

Hydrophobin gene deletion and environmental growth conditions impact mechanical properties of mycelium by affecting the density of the material

(2018) Freek V. W. Appels et al.   Scientific Reports

Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans

(2018) Rasmus J. N. Frandsen et al.   Scientific Reports

Updating genome annotation for the microbial cell factory Aspergillus niger using gene co-expression networks

(2018) P Schäpe et al.   NUCLEIC ACIDS RESEARCH

Engineering of the citrate exporter protein enables high citric acid production in Aspergillus niger

(2018) Matthias G. Steiger et al.   METABOLIC ENGINEERING

Polycistronic gene expression in Aspergillus niger

(2017) Tabea Schuetze et al.   Microbial Cell Factories

Ensembl 2018

(2017) Daniel R Zerbino et al.   NUCLEIC ACIDS RESEARCH

Harnessing fungal nonribosomal cyclodepsipeptide synthetases for mechanistic insights and tailored engineering

(2017) Charlotte Steiniger et al.   Chemical Science

Combining inferred regulatory and reconstructed metabolic networks enhances phenotype prediction in yeast

(2017) Zhuo Wang et al.   PLoS Computational Biology

Comparative genomics and transcriptome analysis of Aspergillus niger and metabolic engineering for citrate production

(2017) Xian Yin et al.   Scientific Reports

Advanced Materials From Fungal Mycelium: Fabrication and Tuning of Physical Properties

(2017) Muhammad Haneef et al.   Scientific Reports

Whole-genome metabolic model of Trichoderma reesei built by comparative reconstruction

(2016) Sandra Castillo et al.   Biotechnology for Biofuels

Apical control of conidiation in Aspergillus nidulans

(2016) Elixabet Oiartzabal-Arano et al.   CURRENT GENETICS

Tet-on, or Tet-off, that is the question: Advanced conditional gene expression in Aspergillus

(2016) Franziska Wanka et al.   FUNGAL GENETICS AND BIOLOGY

CRISPR/Cas9 Based Genome Editing of Penicillium chrysogenum

(2016) C. Pohl et al.   ACS Synthetic Biology

Adenylate Cyclase AcyA Regulates Development, Aflatoxin Biosynthesis and Fungal Virulence in Aspergillus flavus

(2016) Kunlong Yang et al.   Frontiers in Cellular and Infection Microbiology

Regulation of cellulase expression, sporulation, and morphogenesis by velvet family proteins in Trichoderma reesei

(2015) Kuimei Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Development of a genome editing technique using the CRISPR/Cas9 system in the industrial filamentous fungus Aspergillus oryzae

(2015) Takuya Katayama et al.   BIOTECHNOLOGY LETTERS

Genomic mutational analysis of the impact of the classical strain improvement program on β–lactam producing Penicillium chrysogenum

(2015) Oleksandr V. Salo et al.   BMC GENOMICS

The filamentous fungal pellet and forces driving its formation

(2015) Jianguo Zhang et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

The AngFus3 Mitogen-Activated Protein Kinase Controls Hyphal Differentiation and Secondary Metabolism in Aspergillus niger

(2015) Bert-Ewald Priegnitz et al.   EUKARYOTIC CELL

Components of the Calcium-Calcineurin Signaling Pathway in Fungal Cells and Their Potential as Antifungal Targets

(2015) Shuyuan Liu et al.   EUKARYOTIC CELL

Selective transport between heterogeneous hyphal compartments via the plasma membrane lining septal walls of Aspergillus niger

(2015) Robert-Jan Bleichrodt et al.   FUNGAL GENETICS AND BIOLOGY

AcstuA , which encodes an APSES transcription regulator, is involved in conidiation, cephalosporin biosynthesis and cell wall integrity of Acremonium chrysogenum

(2015) Pengjie Hu et al.   FUNGAL GENETICS AND BIOLOGY

Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming ofPenicillium chrysogenum

(2015) Kirsty J. McLean et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial differentiation of gene expression in Aspergillus niger colony grown for sugar beet pulp utilization

(2015) Isabelle Benoit et al.   Scientific Reports

Identification of a Classical Mutant in the Industrial Host Aspergillus niger by Systems Genetics: LaeA Is Required for Citric Acid Production and Regulates the Formation of Some Secondary Metabolites

(2015) Jing Niu et al.   G3-Genes Genomes Genetics

Overview of citric acid production fromAspergillus niger

(2015) Pau Loke Show et al.   Frontiers in Life Science

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

(2015) Vito Valiante et al.   Frontiers in Microbiology

Superresolution microscopy reveals a dynamic picture of cell polarity maintenance during directional growth

(2015) Y. Ishitsuka et al.   Science Advances

Efficient genome editing in filamentous fungus Trichoderma reesei using the CRISPR/Cas9 system

(2015) Rui Liu et al.   Cell Discovery

Genome-scale analysis of the high-efficient protein secretion system of Aspergillus oryzae

(2014) Lifang Liu et al.   BMC Systems Biology

Genomic analysis of the aconidial and high-performance protein producer, industrially relevant Aspergillus niger SH2 strain

(2014) Chao Yin et al.   GENE

The Neurospora crassa exocyst complex tethers Spitzenkörper vesicles to the apical plasma membrane during polarized growth

(2014) Meritxell Riquelme et al.   MOLECULAR BIOLOGY OF THE CELL

The VELVET A Orthologue VEL1 of Trichoderma reesei Regulates Fungal Development and Is Essential for Cellulase Gene Expression

(2014) Razieh Karimi Aghcheh et al.   PLoS One

Adding talc microparticles toAspergillus terreusATCC 20542 preculture decreases fungal pellet size and improves lovastatin production

(2013) Joanna Gonciarz et al.   ENGINEERING IN LIFE SCIENCES

The Spatial Distribution of the Exocyst and Actin Cortical Patches Is Sufficient To Organize Hyphal Tip Growth

(2013) David Caballero-Lima et al.   EUKARYOTIC CELL

The cell-end marker TeaA and the microtubule polymerase AlpA contribute to microtubule guidance at the hyphal tip cortex of Aspergillus nidulans to provide polarity maintenance

(2013) N. Takeshita et al.   JOURNAL OF CELL SCIENCE

TheAspergillusGenome Database: multispecies curation and incorporation of RNA-Seq data to improve structural gene annotations

(2013) Gustavo C. Cerqueira et al.   NUCLEIC ACIDS RESEARCH

MycoCosm portal: gearing up for 1000 fungal genomes

(2013) Igor V. Grigoriev et al.   NUCLEIC ACIDS RESEARCH

The Transcriptomic Signature of RacA Activation and Inactivation Provides New Insights into the Morphogenetic Network of Aspergillus niger

(2013) Min Jin Kwon et al.   PLoS One

Development in Aspergillus

(2013) P. Krijgsheld et al.   STUDIES IN MYCOLOGY

Version 6 of the consensus yeast metabolic network refines biochemical coverage and improves model performance

(2013) Benjamin D. Heavner et al.   Database-The Journal of Biological Databases and Curation

Functional Analyses of Trichoderma reesei LAE1 Reveal Conserved and Contrasting Roles of This Regulator

(2013) Razieh Karimi-Aghcheh et al.   G3-Genes Genomes Genetics

The RAVEN Toolbox and Its Use for Generating a Genome-scale Metabolic Model for Penicillium chrysogenum

(2013) Rasmus Agren et al.   PLoS Computational Biology

Upgrading Fungal Gene Expression on Demand: Improved Systems for Doxycycline-Dependent Silencing in Aspergillus fumigatus

(2012) Christoph Helmschrott et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Roles of Protein Kinase A and Adenylate Cyclase in Light-Modulated Cellulase Regulation in Trichoderma reesei

(2012) André Schuster et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Morphological changes induced by class III chitin synthase gene silencing could enhance penicillin production of Penicillium chrysogenum

(2012) Hui Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The transcriptomic fingerprint of glucoamylase over-expression in Aspergillus niger

(2012) Min Jin Kwon et al.   BMC GENOMICS

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Regulation of fungal secondary metabolism

(2012) Axel A. Brakhage   NATURE REVIEWS MICROBIOLOGY

The Aspergillus nidulans MAPK Module AnSte11-Ste50-Ste7-Fus3 Controls Development and Secondary Metabolism

(2012) Özgür Bayram et al.   PLoS Genetics

Customization of Aspergillus niger Morphology Through Addition of Talc Micro Particles

(2012) Thomas Wucherpfennig et al.   Jove-Journal of Visualized Experiments

Fungal Gene Expression on Demand: an Inducible, Tunable, and Metabolism-Independent Expression System for Aspergillus niger

(2011) Vera Meyer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Total Biosynthesis of Diterpene Aphidicolin, a Specific Inhibitor of DNA Polymerase α: Heterologous Expression of Four Biosynthetic Genes inAspergillus oryzae

(2011) Ryuya FUJII et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Improved enzyme production by bio-pellets of Aspergillus niger: Targeted morphology engineering using titanate microparticles

(2011) Habib Driouch et al.   BIOTECHNOLOGY AND BIOENGINEERING

Putative Stress Sensors WscA and WscB Are Involved in Hypo-Osmotic and Acidic pH Stress Tolerance in Aspergillus nidulans

(2011) Taiki Futagami et al.   EUKARYOTIC CELL

On the role of microtubules, cell end markers, and septal microtubule organizing centres on site selection for polar growth in Aspergillus nidulans

(2011) Norio Takeshita et al.   Fungal Biology

Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88

(2011) M. R. Andersen et al.   GENOME RESEARCH

Effects of Tween 80 and pH on mycelial pellets and exopolysaccharide production in liquid culture of a medicinal fungus

(2011) Yuan-Shuai Liu et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Rational Domain Swaps Decipher Programming in Fungal Highly Reducing Polyketide Synthases and Resurrect an Extinct Metabolite

(2011) Katja M. Fisch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Morphology engineering - Osmolality and its effect on Aspergillus niger morphology and productivity

(2011) Thomas Wucherpfennig et al.   Microbial Cell Factories

Exocytosis and growth do not occur only at hyphal tips

(2011) Nick D. Read   MOLECULAR MICROBIOLOGY

Septum-directed secretion in the filamentous fungus Aspergillus oryzae

(2011) Yugo Hayakawa et al.   MOLECULAR MICROBIOLOGY

Synthetic chromosome arms function in yeast and generate phenotypic diversity by design

(2011) Jessica S. Dymond et al.   NATURE

FungiDB: an integrated functional genomics database for fungi

(2011) J. E. Stajich et al.   NUCLEIC ACIDS RESEARCH

Transcriptomic Insights into the Physiology of Aspergillus niger Approaching a Specific Growth Rate of Zero

(2010) T. R. Jorgensen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Heterochromatic marks are associated with the repression of secondary metabolism clusters in Aspergillus nidulans

(2010) Yazmid Reyes-Dominguez et al.   MOLECULAR MICROBIOLOGY

Functional characterization of Rho GTPases in Aspergillus niger uncovers conserved and diverged roles of Rho proteins within filamentous fungi

(2010) Min Jin Kwon et al.   MOLECULAR MICROBIOLOGY

Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway

(2009) Thomas R Jørgensen et al.   BMC GENOMICS

Reconstruction of Signaling Networks Regulating Fungal Morphogenesis by Transcriptomics

(2009) Vera Meyer et al.   EUKARYOTIC CELL

Morphology and development in Aspergillus nidulans: A complex puzzle

(2009) Steven D. Harris et al.   FUNGAL GENETICS AND BIOLOGY

The Tip Growth Apparatus of Aspergillus nidulans

(2008) Naimeh Taheri-Talesh et al.   MOLECULAR BIOLOGY OF THE CELL

Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA

(2008) Frederico Marianetti Soriani et al.   MOLECULAR MICROBIOLOGY

Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger

(2008) Mikael Rørdam Andersen et al.   Molecular Systems Biology

Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum

(2008) Marco A van den Berg et al.   NATURE BIOTECHNOLOGY

VelB/VeA/LaeA Complex Coordinates Light Signal with Fungal Development and Secondary Metabolism

(2008) O. Bayram et al.   SCIENCE