Involvement of agmatine in antidepressant-like effect of HMG-CoA reductase inhibitors in mice

Simvastatin exerts antidepressant-like activity in mouse forced swimming test: Role of NO-cGMP-KATP channels pathway and PPAR-gamma receptors

(2019) Reza Naserzadeh et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Atorvastatin prevents lipopolysaccharide-induced depressive-like behaviour in mice

(2019) E.H. Taniguti et al.   BRAIN RESEARCH BULLETIN

Neuroprotective offerings by agmatine

(2019) Nandkishor Ramdas Kotagale et al.   NEUROTOXICOLOGY

Inhibitory Influence of Agmatine in Ethanol Withdrawal-Induced Depression in Rats: Behavioral and Neurochemical Evidences

(2019) Niyamat Chimthanawala et al.   ALCOHOL

Agmatine reverses ethanol consumption in rats: Evidences for an interaction with imidazoline receptors

(2019) Brijesh G. Taksande et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Altered plasma levels of arginine metabolites in depression

(2019) Arisoy Ozden et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Modulation of the anticonvulsant effect of swim stress by agmatine

(2018) Taraneh Bahremand et al.   EPILEPSY & BEHAVIOR

Evidence of Reduced Agmatine Concentrations in the Cerebral Cortex of Suicides

(2018) Gary G Chen et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Agmatine inhibits nicotine withdrawal induced cognitive deficits in inhibitory avoidance task in rats: Contribution of α 2 -adrenoceptors

(2018) Nandkishor R. Kotagale et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The neuroprotective effect of agmatine against amyloid β-induced apoptosis in primary cultured hippocampal cells involving ERK, Akt/GSK-3β, and TNF-α

(2018) Etrat Hooshmandi et al.   MOLECULAR BIOLOGY REPORTS

Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats

(2017) Inci Turan et al.   LIFE SCIENCES

Therapeutic potential of agmatine for CNS disorders

(2017) Vivian B. Neis et al.   NEUROCHEMISTRY INTERNATIONAL

Agmatine produces antidepressant-like effects by activating AMPA receptors and mTOR signaling

(2016) Vivian Binder Neis et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Statins for the treatment of depression: A meta-analysis of randomized, double-blind, placebo-controlled trials

(2016) Estela Salagre et al.   JOURNAL OF AFFECTIVE DISORDERS

Involvement of PI3K/Akt/GSK-3β and mTOR in the antidepressant-like effect of atorvastatin in mice

(2016) Fabiana Kalyne Ludka et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Atorvastatin Protects from Aβ1–40-Induced Cell Damage and Depressive-Like Behavior via ProBDNF Cleavage

(2016) Fabiana K. Ludka et al.   MOLECULAR NEUROBIOLOGY

Agmatine Prevents Adaptation of the Hippocampal Glutamate System in Chronic Morphine-Treated Rats

(2016) Xiao-Fei Wang et al.   Neuroscience Bulletin

Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression

(2016) E M Meylan et al.   Translational Psychiatry

Chronic agmatine treatment prevents behavioral manifestations of nicotine withdrawal in mice

(2015) Nandkishor R. Kotagale et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Simvastatin prevents β-amyloid25–35-impaired neurogenesis in hippocampal dentate gyrus through α7nAChR-dependent cascading PI3K-Akt and increasing BDNF via reduction of farnesyl pyrophosphate

(2015) Conghui Wang et al.   NEUROPHARMACOLOGY

Statins Reduce the Risks of Relapse to Addiction in Rats

(2015) Claudia Chauvet et al.   NEUROPSYCHOPHARMACOLOGY

Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1–40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems

(2015) Wagner C. Martins et al.   NEUROTOXICITY RESEARCH

Agmatine attenuates nicotine induced conditioned place preference in mice through modulation of neuropeptide Y system

(2014) Nandkishor R. Kotagale et al.   BEHAVIOURAL BRAIN RESEARCH

Depressive-like behavior induced by tumor necrosis factor-α is abolished by agmatine administration

(2014) Vivian Binder Neis et al.   BEHAVIOURAL BRAIN RESEARCH

Imidazoline binding sites mediates anticompulsive-like effect of agmatine in marble-burying behavior in mice

(2014) Madhura P. Dixit et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Antidepressant-like effect of atorvastatin in the forced swimming test in mice: The role of PPAR-gamma receptor and nitric oxide pathway

(2014) Arash Shahsavarian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuropeptide Y in the central nucleus of amygdala regulates the anxiolytic effect of agmatine in rats

(2014) Brijesh G. Taksande et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Sub-chronic agmatine treatment modulates hippocampal neuroplasticity and cell survival signaling pathways in mice

(2014) Andiara E. Freitas et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Statins in neurological disorders: An overview and update

(2014) Anna Maria Malfitano et al.   PHARMACOLOGICAL RESEARCH

Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice

(2014) Fabiana K. Ludka et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Agmatine: clinical applications after 100 years in translation

(2013) John E. Piletz et al.   DRUG DISCOVERY TODAY

Agmatine attenuates chronic unpredictable mild stress induced behavioral alteration in mice

(2013) Brijesh G. Taksande et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Evidences for the agmatine involvement in antidepressant like effect of bupropion in mouse forced swim test

(2013) Nandkishor R. Kotagale et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms

(2012) Anil Kumar et al.   BRAIN RESEARCH

Acute atorvastatin treatment exerts antidepressant-like effect in mice via the l-arginine–nitric oxide–cyclic guanosine monophosphate pathway and increases BDNF levels

(2012) Fabiana K. Ludka et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Agmatinase, an inactivator of the putative endogenous antidepressant agmatine, is strongly upregulated in hippocampal interneurons of subjects with mood disorders

(2011) Hans-Gert Bernstein et al.   NEUROPHARMACOLOGY

Repeated agmatine treatment attenuates nicotine sensitization in mice: Modulation by α2-adrenoceptors

(2010) Nandkishor Ramdas Kotagale et al.   BEHAVIOURAL BRAIN RESEARCH

Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats

(2010) Brijesh G Taksande et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β1–40 administration in mice: Evidence for dissociation between cognitive deficits and neuronal damage

(2010) Tetsadê C.B. Piermartiri et al.   EXPERIMENTAL NEUROLOGY

Antidepressant like effect of selective serotonin reuptake inhibitors involve modulation of imidazoline receptors by agmatine

(2009) Brijesh G. Taksande et al.   NEUROPHARMACOLOGY

Platelet imidazoline receptors as state marker of depressive symptomatology

(2006) John Piletz et al.   JOURNAL OF PSYCHIATRIC RESEARCH