Simvastatin prevents β-amyloid25–35-impaired neurogenesis in hippocampal dentate gyrus through α7nAChR-dependent cascading PI3K-Akt and increasing BDNF via reduction of farnesyl pyrophosphate

Title
Simvastatin prevents β-amyloid25–35-impaired neurogenesis in hippocampal dentate gyrus through α7nAChR-dependent cascading PI3K-Akt and increasing BDNF via reduction of farnesyl pyrophosphate
Authors
Keywords
Simvastatin (SV), β-Amyloid (Aβ), Neurogenesis, α7 nicotinic acetylcholine receptor (α7nAChR), Farnesyl pyrophosphate (FPP)
Journal
NEUROPHARMACOLOGY
Volume 97, Issue -, Pages 122-132
Publisher
Elsevier BV
Online
2015-06-06
DOI
10.1016/j.neuropharm.2015.05.020

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