Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression

Agmatine produces antidepressant-like effects by activating AMPA receptors and mTOR signaling

(2016) Vivian Binder Neis et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression

(2016) Elsa M. Meylan et al.   NEUROPHARMACOLOGY

Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics

(2015) Chadi G. Abdallah et al.   Annual Review of Medicine

Agmatine enhances antidepressant potency of MK-801 and conventional antidepressants in mice

(2015) Vivian Binder Neis et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Crtc1 Activates a Transcriptional Program Deregulated at Early Alzheimer's Disease-Related Stages

(2014) A. Parra-Damas et al.   JOURNAL OF NEUROSCIENCE

Sub-chronic agmatine treatment modulates hippocampal neuroplasticity and cell survival signaling pathways in mice

(2014) Andiara E. Freitas et al.   JOURNAL OF PSYCHIATRIC RESEARCH

The molecular bases of the suicidal brain

(2014) Gustavo Turecki   NATURE REVIEWS NEUROSCIENCE

Rapid-Acting Glutamatergic Antidepressants: The Path to Ketamine and Beyond

(2013) John H. Krystal et al.   BIOLOGICAL PSYCHIATRY

Agmatine: clinical applications after 100 years in translation

(2013) John E. Piletz et al.   DRUG DISCOVERY TODAY

Agmatine attenuates chronic unpredictable mild stress induced behavioral alteration in mice

(2013) Brijesh G. Taksande et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice

(2013) Andiara E. Freitas et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Deletion of CREB-Regulated Transcription Coactivator 1 Induces Pathological Aggression, Depression-Related Behaviors, and Neuroplasticity Genes Dysregulation in Mice

(2012) Lionel Breuillaud et al.   BIOLOGICAL PSYCHIATRY

The Role of Eukaryotic Elongation Factor 2 Kinase in Rapid Antidepressant Action of Ketamine

(2012) Lisa M. Monteggia et al.   BIOLOGICAL PSYCHIATRY

Activity-Dependent Transport of the Transcriptional Coactivator CRTC1 from Synapse to Nucleus

(2012) Toh Hean Ch'ng et al.   CELL

Hippocampal nitric oxide contributes to sex difference in affective behaviors

(2012) Y. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Agmatinase, an inactivator of the putative endogenous antidepressant agmatine, is strongly upregulated in hippocampal interneurons of subjects with mood disorders

(2011) Hans-Gert Bernstein et al.   NEUROPHARMACOLOGY

The pharmacological importance of agmatine in the brain

(2011) Tayfun I. Uzbay   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The agmatine-degrading enzyme agmatinase: a key to agmatine signaling in rat and human brain?

(2010) H.-G. Bernstein et al.   AMINO ACIDS

Regulation of Dendritic Development by BDNF Requires Activation of CRTC1 by Glutamate

(2010) Charles Finsterwald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Gender-Specific Impact of Brain-Derived Neurotrophic Factor Signaling on Stress-Induced Depression-Like Behavior

(2009) Anita E. Autry et al.   BIOLOGICAL PSYCHIATRY

TORC1 Regulates Activity-Dependent CREB-Target Gene Transcription and Dendritic Growth of Developing Cortical Neurons

(2009) S. Li et al.   JOURNAL OF NEUROSCIENCE

Mouse fertility is not dependent on the CREB coactivator Crtc1

(2009) Lionel Breuillaud et al.   NATURE MEDICINE

Antidepressant like effect of selective serotonin reuptake inhibitors involve modulation of imidazoline receptors by agmatine

(2009) Brijesh G. Taksande et al.   NEUROPHARMACOLOGY

Exogenous agmatine has neuroprotective effects against restraint-induced structural changes in the rat brain

(2008) Meng-Yang Zhu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Repeated immobilization stress alters rat hippocampal and prefrontal cortical morphology in parallel with endogenous agmatine and arginine decarboxylase levels

(2008) Meng-Yang Zhu et al.   NEUROCHEMISTRY INTERNATIONAL

Somatostatinergic systems in brain: Networks and functions

(2007) Cécile Viollet et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY