Drp1-mediated mitochondrial fission contributes to mitophagy in paraquat-induced neuronal cell damage

Cyclosporine attenuates Paraquat-induced mitophagy and pulmonary fibrosis

(2020) Kaixiang Liu et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease

(2020) Preston Ge et al.   Molecular Neurodegeneration

Redox toxicology of environmental chemicals causing oxidative stress

(2020) Fuli Zheng et al.   Redox Biology

LncRNA NR_030777 Alleviates Paraquat-induced Neurotoxicity by Regulating Zfp326 and Cpne5

(2020) Hongyu Yang et al.   TOXICOLOGICAL SCIENCES

LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson’s disease

(2019) Fiona Bonello et al.   HUMAN MOLECULAR GENETICS

Elucidating Conserved Transcriptional Networks Underlying Pesticide Exposure and Parkinson's Disease: A Focus on Chemicals of Epidemiological Relevance

(2019) Fangjie Cao et al.   Frontiers in Genetics

Toxicity of blue led light and A2E is associated to mitochondrial dynamics impairment in ARPE-19 cells: implications for age-related macular degeneration

(2019) Agustina Alaimo et al.   ARCHIVES OF TOXICOLOGY

Early- vs late-start levodopa relieved symptoms but did not affect disease progression in Parkinson disease

(2019) Joseph H. Friedman   ANNALS OF INTERNAL MEDICINE

FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy

(2019) Marc P. M. Soutar et al.   Autophagy

Modafinil protects hippocampal neurons by suppressing excessive autophagy and apoptosis in mice with sleep deprivation

(2019) Yin Cao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Environment, lifestyle, and Parkinson's disease: Implications for prevention in the next decade

(2019) Connie Marras et al.   MOVEMENT DISORDERS

Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease

(2019) P. Hemachandra Reddy et al.   Cells

Autophagy in Neurons

(2019) Andrea K.H. Stavoe et al.   Annual Review of Cell and Developmental Biology

LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease

(2019) Bradlee L. Heckmann et al.   CELL

Autophagy Stimulation Decreases Dopaminergic Neuronal Death Mediated by Oxidative Stress

(2019) Marcela J. Ramirez-Moreno et al.   MOLECULAR NEUROBIOLOGY

Nrf2-regulated miR-380-3p blocks the translation of Sp3 protein and its mediation of paraquat-induced toxicity in mouse neuroblastoma N2a cells

(2019) Zhipeng Cai et al.   TOXICOLOGICAL SCIENCES

USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy

(2019) Kaifeng Niu et al.   Autophagy

Oxidative stress in vagal neurons promotes parkinsonian pathology and intercellular α-synuclein transfer

(2019) Ruth E. Musgrove et al.   JOURNAL OF CLINICAL INVESTIGATION

Parkinson disease genetics: too early to predict progression?

(2019) Gregor Kuhlenbäumer et al.   Nature Reviews Neurology

ROCK1 induces dopaminergic nerve cell apoptosis via the activation of Drp1-mediated aberrant mitochondrial fission in Parkinson’s disease

(2019) Qian Zhang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Paraquat exposure delays late-stage Leydig cell differentiation in rats during puberty

(2019) Huitao Li et al.   ENVIRONMENTAL POLLUTION

Emerging concepts of mitochondrial dysfunction in Parkinson’s disease progression: Pathogenic and therapeutic implications

(2019) Linchi Rani et al.   MITOCHONDRION

Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance

(2018) Allyson L. Anding et al.   CURRENT BIOLOGY

Toxicological responses on cytochrome P450 and metabolic transferases in liver of goldfish ( Carassius auratus ) exposed to lead and paraquat

(2018) Xiaoming Xu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Role of autophagy in environmental neurotoxicity

(2018) C. Pellacani et al.   ENVIRONMENTAL POLLUTION

Drp-1 dependent mitochondrial fragmentation and protective autophagy in dopaminergic SH-SY5Y cells overexpressing alpha-synuclein

(2018) Jimena Hebe Martinez et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton

(2018) Dalila G. Ordonez et al.   NEURON

Paraquat and MPTP induce alteration in the expression profile of long noncoding RNAs in the substantia nigra of mice: Role of the transcription factor Nrf2

(2018) Lijin Wang et al.   TOXICOLOGY LETTERS

Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease

(2018) Shankar J. Chinta et al.   Cell Reports

Environmental fate and ecotoxicology of paraquat: a California perspective

(2018) Fabio Sartori et al.   TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY

Diverse mechanisms of autophagy dysregulation and their therapeutic implications: does the shoe fit?

(2018) Paalini Sathiyaseelan et al.   Autophagy

Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells

(2018) Da-Zhuang Sun et al.   TOXICOLOGY IN VITRO

Mitochondrial dysfunction and oxidative stress in induced pluripotent stem cell models of Parkinson's disease

(2018) Anindita Bose et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

PBPK/PD assessment for Parkinson’s disease risk posed by airborne pesticide paraquat exposure

(2017) Yi-Hsien Cheng et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Crosstalk between Mitochondrial Fission and Oxidative Stress in Paraquat-Induced Apoptosis in Mouse Alveolar Type II Cells

(2017) Guangju Zhao et al.   International Journal of Biological Sciences

Paraquat and MPTP alter microRNA expression profiles, and downregulated expression of miR-17-5p contributes to PQ-induced dopaminergic neurodegeneration

(2017) Qingqing Wang et al.   JOURNAL OF APPLIED TOXICOLOGY

The Essential Role of Drp1 and Its Regulation by S-Nitrosylation of Parkin in Dopaminergic Neurodegeneration: Implications for Parkinson's Disease

(2016) Zhenzhen Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Pesticides: an update of human exposure and toxicity

(2016) Sara Mostafalou et al.   ARCHIVES OF TOXICOLOGY

Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy

(2016) Ming Chen et al.   Autophagy

Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy

(2016) Shun-ichi Yamashita et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial dysfunction in Parkinson's disease

(2016) Anindita Bose et al.   JOURNAL OF NEUROCHEMISTRY

Melatonin prevents the dynamin-related protein 1-dependent mitochondrial fission and oxidative insult in the cortical neurons after 1-methyl-4-phenylpyridinium treatment

(2016) Jih-Ing Chuang et al.   JOURNAL OF PINEAL RESEARCH

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy

(2016) Thanh N. Nguyen et al.   TRENDS IN CELL BIOLOGY

Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson’s disease model induced by MPTP

(2016) Emily Filichia et al.   Scientific Reports

Mitochondrial quality control: Easy come, easy go

(2015) Aleksandr Stotland et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts

(2015) Moshi Song et al.   Cell Metabolism

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability

(2015) Chuen-Lin Huang et al.   MOLECULAR NEUROBIOLOGY

The prevalence of Parkinson's disease: A systematic review and meta-analysis

(2014) Tamara Pringsheim et al.   MOVEMENT DISORDERS

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

(2014) Baris Bingol et al.   NATURE

Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases—A mechanistic approach

(2014) Maria Teresa Baltazar et al.   TOXICOLOGY LETTERS

Fibroblasts from long-lived mutant mice exhibit increased autophagy and lower TOR activity after nutrient deprivation or oxidative stress

(2012) Min Wang et al.   AGING CELL

Neuroprotective effects of tert-butylhydroquinone on paraquat-induced dopaminergic cell degeneration in C57BL/6 mice and in PC12 cells

(2012) Huangyuan Li et al.   ARCHIVES OF TOXICOLOGY

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS

Differentiation of mouse Neuro 2A cells into dopamine neurons

(2009) Roger G. Tremblay et al.   JOURNAL OF NEUROSCIENCE METHODS