Functional interrogation of DNA damage response variants with base editing screens
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Title
Functional interrogation of DNA damage response variants with base editing screens
Authors
Keywords
DNA damage response, CRISPR-dependent base editing, BE3 base editor, 53BP1, ATM, TRAIP, CHK2, clinically relevant variants, variants of uncertain significance
Journal
CELL
Volume 184, Issue 4, Pages 1081-1097.e19
Publisher
Elsevier BV
Online
2021-02-19
DOI
10.1016/j.cell.2021.01.041
References
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