A comprehensive survey for human transcription factors on expression, regulation, interaction, phenotype and cancer survival

Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions

(2020) Ignacio L. Ibarra et al.   Nature Communications

LncSpA: LncRNA Spatial Atlas of Expression across Normal and Cancer Tissues

(2020) Dezhong Lv et al.   CANCER RESEARCH

VHL mutation-mediated SALL4 overexpression promotes tumorigenesis and vascularization of clear cell renal cell carcinoma via Akt/GSK-3β signaling

(2020) Jinbo Sun et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets

(2020) Qiong Zhang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Genomic characterization of metastatic breast cancers

(2019) François Bertucci et al.   NATURE

STAT6 knockdown using multiple siRNA sequences inhibits proliferation and induces apoptosis of human colorectal and breast cancer cell lines

(2019) Carmen Salguero-Aranda et al.   PLoS One

Sweeten Almonds: A Single Mutation in the bHLH2 Transcription Factor

(2019) Jie Wu et al.   TRENDS IN PLANT SCIENCE

Landscape of cancer diagnostic biomarkers from specifically expressed genes

(2019) Yao Lv et al.   BRIEFINGS IN BIOINFORMATICS

GSCALite: a web server for gene set cancer analysis

(2018) Chun-Jie Liu et al.   BIOINFORMATICS

The Human Transcription Factors

(2018) Samuel A. Lambert et al.   CELL

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation

(2018) Joanna J. Gell et al.   Stem Cell Research

CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation

(2018) Veronica Garcia-Carpizo et al.   Epigenetics & Chromatin

Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility

(2018) Vivek Behera et al.   Nature Communications

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

(2018) Yakir A. Reshef et al.   NATURE GENETICS

AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors

(2018) Hui Hu et al.   NUCLEIC ACIDS RESEARCH

The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies

(2018) Loukik Arora et al.   Cancers

Building Transcription Factor Binding Site Models to Understand Gene Regulation in Plants

(2018) Xuelei Lai et al.   Molecular Plant

Utility of Phox2b immunohistochemical stain in neural crest tumours and non-neural crest tumours in paediatric patients

(2017) Mikako Warren et al.   HISTOPATHOLOGY

GATA Transcription Factors: Basic Principles and Related Human Disorders

(2017) Tohru Fujiwara   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Aberrant DNA methylation and expression of SPDEF and FOXA2 in airway epithelium of patients with COPD

(2017) J. Song et al.   Clinical Epigenetics

Transcription Factor Drug Targets

(2016) Kostas A. Papavassiliou et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A decade of transcription factor-mediated reprogramming to pluripotency

(2016) Kazutoshi Takahashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Evolution and diversification of the basal transcription machinery

(2015) Sascha H.C. Duttke   TRENDS IN BIOCHEMICAL SCIENCES

Co-regulation in embryonic stem cells via context-dependent binding of transcription factors

(2013) Yuju Lee et al.   BIOINFORMATICS

Transcription factor and microRNA co-regulatory loops: important regulatory motifs in biological processes and diseases

(2013) H.-M. Zhang et al.   BRIEFINGS IN BIOINFORMATICS

ELF3 is a repressor of androgen receptor action in prostate cancer cells

(2013) A Shatnawi et al.   ONCOGENE

Networks of bZIP Protein-Protein Interactions Diversified Over a Billion Years of Evolution

(2013) A. W. Reinke et al.   SCIENCE

Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner

(2012) J. Gertz et al.   GENOME RESEARCH

Specification of the germ cell lineage in mice: A process orchestrated by the PR-domain proteins, Blimp1 and Prdm14

(2011) Kazuki Kurimoto et al.   CELL CYCLE

Prdm14 initiates lymphoblastic leukemia after expanding a population of cells resembling common lymphoid progenitors

(2011) E J Dettman et al.   ONCOGENE

An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man

(2010) Timothy Ravasi et al.   CELL

Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation

(2010) L. Thorrez et al.   GENOME RESEARCH

A census of human transcription factors: function, expression and evolution

(2009) Juan M. Vaquerizas et al.   NATURE REVIEWS GENETICS

HMGB4, a Novel Member of the HMGB Family, Is Preferentially Expressed in the Mouse Testis and Localizes to the Basal Pole of Elongating Spermatids1

(2008) Raffaella Catena et al.   BIOLOGY OF REPRODUCTION

Patterns of evolutionary constraints on genes in humans

(2008) Subhajyoti De et al.   BMC EVOLUTIONARY BIOLOGY

Transgenic analyses of TGIF family proteins in Drosophila imply their role in cell growth

(2008) Yonghua Wang et al.   Journal of Genetics and Genomics

Critical function of Prdm14 for the establishment of the germ cell lineage in mice

(2008) Masashi Yamaji et al.   NATURE GENETICS

Functional protein divergence in the evolution of Homo sapiens

(2008) Nuria Lopez-Bigas et al.   GENOME BIOLOGY