Aberrant DNA methylation and expression of SPDEF and FOXA2 in airway epithelium of patients with COPD

The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development

(2016) James P. Allinson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Azithromycin differentially affects the IL-13-induced expression profile in human bronchial epithelial cells

(2016) Tinne C.J. Mertens et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Distal airways are protected from goblet cell metaplasia by diminished expression of IL-13 signalling components

(2015) C. Vock et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation

(2015) Priya Rajavelu et al.   JOURNAL OF CLINICAL INVESTIGATION

Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells

(2015) L. E. M. Kistemaker et al.   THORAX

Expression and Regulation of Transcription Factor FoxA2 in Chronic Rhinosinusitis With and Without Nasal Polyps

(2015) Qing Luo et al.   Allergy Asthma & Immunology Research

Abnormalities in Airway Epithelial Junction Formation in Chronic Obstructive Pulmonary Disease

(2014) Irene H. Heijink et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Airway Basal Cells. The “Smoking Gun” of Chronic Obstructive Pulmonary Disease

(2014) Ronald G. Crystal   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Foxa3 Induces Goblet Cell Metaplasia and Inhibits Innate Antiviral Immunity

(2014) Gang Chen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

(2014) Brigid L.M. Hogan et al.   Cell Stem Cell

Lung development: orchestrating the generation and regeneration of a complex organ

(2014) M. Herriges et al.   DEVELOPMENT

DNA methylation is required for the control of stem cell differentiation in the small intestine

(2014) K. L. Sheaffer et al.   GENES & DEVELOPMENT

Paradoxical Role of DNA Methylation in Activation of FoxA2 Gene Expression during Endoderm Development

(2014) Keren Bahar Halpern et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced expression of SAM-pointed domain-containing Ets-like factor in Chronic rhinosinusitis with nasal polyps

(2014) Jing Bai et al.   LARYNGOSCOPE

DNA methylation dynamics during ex vivo differentiation and maturation of human dendritic cells

(2014) Xue Zhang et al.   Epigenetics & Chromatin

Foxa2 Regulates Leukotrienes to Inhibit Th2-mediated Pulmonary Inflammation

(2013) Xiaoju Tang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression

(2012) S. A. Selamat et al.   GENOME RESEARCH

Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing

(2012) Daniela S. Basseres et al.   LUNG CANCER

DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells

(2012) Christoph Bock et al.   MOLECULAR CELL

Airway Epithelial Transcription Factor NK2 Homeobox 1 Inhibits Mucous Cell Metaplasia and Th2 Inflammation

(2011) Yutaka Maeda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interleukin-13 Induces Mucin 5AC Production Involving STAT6/SPDEF in Human Airway Epithelial Cells

(2011) Hongmei Yu et al.   CELL COMMUNICATION AND ADHESION

Pseudomonas aeruginosa pyocyanin causes airway goblet cell hyperplasia and metaplasia and mucus hypersecretion by inactivating the transcriptional factor FoxA2

(2011) Yonghua Hao et al.   CELLULAR MICROBIOLOGY

MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis

(2011) Yasuyuki Hosono et al.   EMBO JOURNAL

DNA Methylation of the First Exon Is Tightly Linked to Transcriptional Silencing

(2011) Fabienne Brenet et al.   PLoS One

Cough and sputum production as risk factors for poor outcomes in patients with COPD

(2011) Marc Miravitlles   RESPIRATORY MEDICINE

DNA methylation in stem cell renewal and multipotency

(2011) María Berdasco et al.   Stem Cell Research & Therapy

Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo

(2010) Renat Shaykhiev et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

(2010) J. R. Rock et al.   Disease Models & Mechanisms

Foxa2 Programs Th2 Cell-Mediated Innate Immunity in the Developing Lung

(2010) G. Chen et al.   JOURNAL OF IMMUNOLOGY

Distinct Roles of FOXA2 and FOXA3 in Allergic Airway Disease and Asthma

(2009) Sung-Woo Park et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

House Dust Mite–Promoted Epithelial-to-Mesenchymal Transition in Human Bronchial Epithelium

(2009) Irene H. Heijink et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo

(2009) I. Burtscher et al.   DEVELOPMENT

Epigenetic Mechanisms Modulate Thyroid Transcription Factor 1-mediated Transcription of the Surfactant Protein B Gene

(2009) Yuxia Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents

(2009) Songcang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium

(2008) Sriram Sridhar et al.   BMC GENOMICS