- Home
- Publications
- Publication Search
- Publication Details
Title
Genomic characterization of metastatic breast cancers
Authors
Keywords
-
Journal
NATURE
Volume 569, Issue 7757, Pages 560-564
Publisher
Springer Science and Business Media LLC
Online
2019-05-23
DOI
10.1038/s41586-019-1056-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Phase III Randomized Study of Ribociclib and Fulvestrant in Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: MONALEESA-3
- (2018) Dennis J. Slamon et al. JOURNAL OF CLINICAL ONCOLOGY
- Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial
- (2018) Debu Tripathy et al. LANCET ONCOLOGY
- KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function
- (2018) Kinisha Gala et al. ONCOGENE
- The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers
- (2018) Pedram Razavi et al. CANCER CELL
- Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway
- (2018) Zhiqiang Li et al. CANCER CELL
- Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies
- (2018) Utthara Nayar et al. NATURE GENETICS
- A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
- (2017) Paz Polak et al. NATURE GENETICS
- Pan-cancer analysis of bi-allelic alterations in homologous recombination DNA repair genes
- (2017) Nadeem Riaz et al. Nature Communications
- Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations
- (2017) David Brown et al. Nature Communications
- Accelerating Discovery of Functional Mutant Alleles in Cancer
- (2017) Matthew T. Chang et al. Cancer Discovery
- High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial
- (2017) Christophe Massard et al. Cancer Discovery
- 3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets
- (2017) Jianjiong Gao et al. Genome Medicine
- Somatic mutation, copy number and transcriptomic profiles of primary and matched metastatic estrogen receptor-positive breast cancers
- (2016) D. Fumagalli et al. ANNALS OF ONCOLOGY
- The Genomic Landscape of Male Breast Cancers
- (2016) Salvatore Piscuoglio et al. CLINICAL CANCER RESEARCH
- Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers
- (2016) Rebecca Lock et al. JOURNAL OF CLINICAL INVESTIGATION
- Integrated digital error suppression for improved detection of circulating tumor DNA
- (2016) Aaron M Newman et al. NATURE BIOTECHNOLOGY
- Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer
- (2016) Gabriel N. Hortobagyi et al. NEW ENGLAND JOURNAL OF MEDICINE
- FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing
- (2016) Ronglai Shen et al. NUCLEIC ACIDS RESEARCH
- Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
- (2016) N. McGranahan et al. SCIENCE
- pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens
- (2016) Jasreet Hundal et al. Genome Medicine
- Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis
- (2016) Celine Lefebvre et al. PLOS MEDICINE
- The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program “CASCADE”
- (2016) Peter Savas et al. PLOS MEDICINE
- The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer
- (2016) E. K. Law et al. Science Advances
- Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
- (2015) Christophe Le Tourneau et al. LANCET ONCOLOGY
- Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer
- (2015) Muhammed Murtaza et al. Nature Communications
- Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
- (2015) P. K. Brastianos et al. Cancer Discovery
- Socrates: identification of genomic rearrangements in tumour genomes by re-aligning soft clipped reads
- (2014) Jan Schröder et al. BIOINFORMATICS
- Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER)
- (2014) Fabrice André et al. LANCET ONCOLOGY
- Clonal evolution in breast cancer revealed by single nucleus genome sequencing
- (2014) Yong Wang et al. NATURE
- PyClone: statistical inference of clonal population structure in cancer
- (2014) Andrew Roth et al. NATURE METHODS
- Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR-TKI Therapy in 155 Patients with EGFR-Mutant Lung Cancers
- (2013) H. A. Yu et al. CLINICAL CANCER RESEARCH
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
- (2013) Kristian Cibulskis et al. NATURE BIOTECHNOLOGY
- Activating ESR1 mutations in hormone-resistant metastatic breast cancer
- (2013) Dan R Robinson et al. NATURE GENETICS
- Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure
- (2013) Manli Shen et al. NUCLEIC ACIDS RESEARCH
- Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs
- (2012) Christopher T. Saunders et al. BIOINFORMATICS
- Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation
- (2012) T. Popova et al. CANCER RESEARCH
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tumour evolution inferred by single-cell sequencing
- (2011) Nicholas Navin et al. NATURE
- Targeting the RB-pathway in Cancer Therapy
- (2010) E. S. Knudsen et al. CLINICAL CANCER RESEARCH
- The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
- (2010) A. McKenna et al. GENOME RESEARCH
- Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads
- (2009) K. Ye et al. BIOINFORMATICS
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- Resistance to Tyrosine Kinase Inhibitors in Gastrointestinal Stromal Tumors
- (2009) A. W. Gramza et al. CLINICAL CANCER RESEARCH
- Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
- (2008) Wataru Sakai et al. NATURE
- Resistance to therapy caused by intragenic deletion in BRCA2
- (2008) Stacey L. Edwards et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More