A decade of transcription factor-mediated reprogramming to pluripotency
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A decade of transcription factor-mediated reprogramming to pluripotency
Authors
Keywords
-
Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 17, Issue 3, Pages 183-193
Publisher
Springer Nature
Online
2016-02-17
DOI
10.1038/nrm.2016.8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency
- (2015) Davide Cacchiarelli et al. CELL
- Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells
- (2015) Edward J. Grow et al. NATURE
- A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs
- (2015) Jiho Choi et al. NATURE BIOTECHNOLOGY
- Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments
- (2015) Margaret A. Goodell et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency
- (2015) Hongwei Chen et al. Nature Communications
- KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency
- (2015) Shin-Il Kim et al. Stem Cell Reports
- Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human
- (2014) Yasuhiro Takashima et al. CELL
- Human Somatic Cell Nuclear Transfer Using Adult Cells
- (2014) Young Gie Chung et al. Cell Stem Cell
- Comparable Frequencies of Coding Mutations and Loss of Imprinting in Human Pluripotent Cells Derived by Nuclear Transfer and Defined Factors
- (2014) Bjarki Johannesson et al. Cell Stem Cell
- Tet and TDG Mediate DNA Demethylation Essential for Mesenchymal-to-Epithelial Transition in Somatic Cell Reprogramming
- (2014) Xiao Hu et al. Cell Stem Cell
- Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency
- (2014) Thorold W. Theunissen et al. Cell Stem Cell
- Histone Variants Enriched in Oocytes Enhance Reprogramming to Induced Pluripotent Stem Cells
- (2014) Toshie Shinagawa et al. Cell Stem Cell
- Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells
- (2014) Mitsutoshi Yamada et al. NATURE
- Abnormalities in human pluripotent cells due to reprogramming mechanisms
- (2014) Hong Ma et al. NATURE
- Derivation of naive human embryonic stem cells
- (2014) C. B. Ware et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential
- (2014) M. Ohnuki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defining an essential transcription factor program for naive pluripotency
- (2014) S.- J. Dunn et al. SCIENCE
- A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells
- (2014) Masato Nakagawa et al. Scientific Reports
- Single-Cell Gene Expression Profiles Define Self-Renewing, Pluripotent, and Lineage Primed States of Human Pluripotent Stem Cells
- (2014) Shelley R. Hough et al. Stem Cell Reports
- Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers
- (2013) Jian Shu et al. CELL
- Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells
- (2013) Wei Xie et al. CELL
- Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer
- (2013) Masahito Tachibana et al. CELL
- Induction of a Human Pluripotent State with Distinct Regulatory Circuitry that Resembles Preimplantation Epiblast
- (2013) Yun-Shen Chan et al. Cell Stem Cell
- Reprogramming of Human Fibroblasts to Pluripotency with Lineage Specifiers
- (2013) Nuria Montserrat et al. Cell Stem Cell
- The let-7/LIN-41 Pathway Regulates Reprogramming to Human Induced Pluripotent Stem Cells by Controlling Expression of Prodifferentiation Genes
- (2013) Kathleen A. Worringer et al. Cell Stem Cell
- High-resolution analysis with novel cell-surface markers identifies routes to iPS cells
- (2013) James O’Malley et al. NATURE
- Derivation of novel human ground state naive pluripotent stem cells
- (2013) Ohad Gafni et al. NATURE
- Mechanisms and models of somatic cell reprogramming
- (2013) Yosef Buganim et al. NATURE REVIEWS GENETICS
- Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts
- (2013) K. Tanabe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells
- (2013) M. Koyanagi-Aoi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds
- (2013) P. Hou et al. SCIENCE
- The Polycomb Protein Ezh2 Impacts on Induced Pluripotent Stem Cell Generation
- (2013) Xiaolei Ding et al. STEM CELLS AND DEVELOPMENT
- Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome
- (2012) Abdenour Soufi et al. CELL
- A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells
- (2012) Jose M. Polo et al. CELL
- Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase
- (2012) Yosef Buganim et al. CELL
- Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal
- (2012) Jin Zhang et al. Cell Stem Cell
- Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells
- (2012) Nicola Festuccia et al. Cell Stem Cell
- Induced Pluripotent Stem Cells: Past, Present, and Future
- (2012) Shinya Yamanaka Cell Stem Cell
- Embryonic stem cell trials for macular degeneration: a preliminary report
- (2012) Steven D Schwartz et al. LANCET
- Chromatin-modifying enzymes as modulators of reprogramming
- (2012) Tamer T. Onder et al. NATURE
- Pre-Evaluated Safe Human iPSC-Derived Neural Stem Cells Promote Functional Recovery after Spinal Cord Injury in Common Marmoset without Tumorigenicity
- (2012) Yoshiomi Kobayashi et al. PLoS One
- Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells
- (2012) Takamichi Miyazaki et al. Nature Communications
- A novel xeno-free and feeder-cell-free system for human pluripotent stem cell culture
- (2012) Qihui Wang et al. Protein & Cell
- Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network
- (2011) Yen-Sin Ang et al. CELL
- The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
- (2011) Athanasia D Panopoulos et al. CELL RESEARCH
- Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells
- (2011) Bryce W. Carey et al. Cell Stem Cell
- The Histone Demethylases Jhdm1a/1b Enhance Somatic Cell Reprogramming in a Vitamin-C-Dependent Manner
- (2011) Tao Wang et al. Cell Stem Cell
- De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state
- (2011) M. Pawlak et al. GENES & DEVELOPMENT
- Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells
- (2011) Kazim H. Narsinh et al. JOURNAL OF CLINICAL INVESTIGATION
- Chemically defined conditions for human iPSC derivation and culture
- (2011) Guokai Chen et al. NATURE METHODS
- A more efficient method to generate integration-free human iPS cells
- (2011) Keisuke Okita et al. NATURE METHODS
- Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
- (2010) Jian Yang et al. Cell Stem Cell
- The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells
- (2010) Jian-Chien Dominic Heng et al. Cell Stem Cell
- Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
- (2010) Luigi Warren et al. Cell Stem Cell
- A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts
- (2010) Ronghui Li et al. Cell Stem Cell
- Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming
- (2010) Payman Samavarchi-Tehrani et al. Cell Stem Cell
- Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1
- (2010) M. J. Edel et al. GENES & DEVELOPMENT
- Butyrate Promotes Induced Pluripotent Stem Cell Generation
- (2010) Gaoyang Liang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Development of Defective and Persistent Sendai Virus Vector
- (2010) Ken Nishimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tbx3 improves the germ-line competency of induced pluripotent stem cells
- (2010) Jianyong Han et al. NATURE
- Direct conversion of fibroblasts to functional neurons by defined factors
- (2010) Thomas Vierbuchen et al. NATURE
- A nonviral minicircle vector for deriving human iPS cells
- (2010) Fangjun Jia et al. NATURE METHODS
- A Defined and Xeno-Free Culture Method Enabling the Establishment of Clinical-Grade Human Embryonic, Induced Pluripotent and Adipose Stem Cells
- (2010) Kristiina Rajala et al. PLoS One
- Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury
- (2010) Osahiko Tsuji et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Promotion of direct reprogramming by transformation-deficient Myc
- (2010) M. Nakagawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
- (2010) J. Hanna et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sox2 expression effects on direct reprogramming efficiency as determined by alternative somatic cell fate
- (2010) Shinpei Yamaguchi et al. Stem Cell Research
- Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes
- (2010) Prashant Mali et al. STEM CELLS
- Pluripotent Reprogramming of Fibroblasts by Lentiviralmediated Insertion of SOX2, C-MYC, and TCL-1A
- (2010) Virgínia Picanço-Castro et al. STEM CELLS AND DEVELOPMENT
- Role of the Murine Reprogramming Factors in the Induction of Pluripotency
- (2009) Rupa Sridharan et al. CELL
- iPS Cells Can Support Full-Term Development of Tetraploid Blastocyst-Complemented Embryos
- (2009) Lan Kang et al. Cell Stem Cell
- Molecules that Promote or Enhance Reprogramming of Somatic Cells to Induced Pluripotent Stem Cells
- (2009) Bo Feng et al. Cell Stem Cell
- Naive and Primed Pluripotent States
- (2009) Jennifer Nichols et al. Cell Stem Cell
- Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins
- (2009) Dohoon Kim et al. Cell Stem Cell
- Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins
- (2009) Hongyan Zhou et al. Cell Stem Cell
- Senescence impairs successful reprogramming to pluripotent stem cells
- (2009) A. Banito et al. GENES & DEVELOPMENT
- Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts
- (2009) Noriko Tsubooka et al. GENES TO CELLS
- Elite and stochastic models for induced pluripotent stem cell generation
- (2009) Shinya Yamanaka NATURE
- Small but effective moves towards a greener China
- (2009) Wanxin Li NATURE
- Adult mice generated from induced pluripotent stem cells
- (2009) Michael J. Boland et al. NATURE
- A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
- (2009) Hitoshi Niwa et al. NATURE
- Linking the p53 tumour suppressor pathway to somatic cell reprogramming
- (2009) Teruhisa Kawamura et al. NATURE
- Virus-free induction of pluripotency and subsequent excision of reprogramming factors
- (2009) Keisuke Kaji et al. NATURE
- iPS cells produce viable mice through tetraploid complementation
- (2009) Xiao-yang Zhao et al. NATURE
- piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
- (2009) Knut Woltjen et al. NATURE
- A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
- (2009) Rosa M. Marión et al. NATURE
- Direct cell reprogramming is a stochastic process amenable to acceleration
- (2009) Jacob Hanna et al. NATURE
- Suppression of induced pluripotent stem cell generation by the p53–p21 pathway
- (2009) Hyenjong Hong et al. NATURE
- Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
- (2009) Jochen Utikal et al. NATURE
- Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming
- (2009) Jie Deng et al. NATURE BIOTECHNOLOGY
- Embryonic stem cell–specific microRNAs promote induced pluripotency
- (2009) Robert L Judson et al. NATURE BIOTECHNOLOGY
- Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells
- (2009) Elayne M Chan et al. NATURE BIOTECHNOLOGY
- Variation in the safety of induced pluripotent stem cell lines
- (2009) Kyoko Miura et al. NATURE BIOTECHNOLOGY
- Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
- (2009) Dirk Hockemeyer et al. NATURE BIOTECHNOLOGY
- Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb
- (2009) Bo Feng et al. NATURE CELL BIOLOGY
- Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
- (2009) Kosuke Yusa et al. NATURE METHODS
- Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
- (2009) Noemi FUSAKI et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation
- (2009) E. P. Papapetrou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
- (2009) J. Yu et al. SCIENCE
- Human-Induced Pluripotent Stem Cells Produced Under Xeno-Free Conditions
- (2009) Pablo Juan Ross et al. STEM CELLS AND DEVELOPMENT
- Disease-Specific Induced Pluripotent Stem Cells
- (2008) In-Hyun Park et al. CELL
- Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency
- (2008) Jacob Hanna et al. CELL
- Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse
- (2008) Matthias Stadtfeld et al. Cell Stem Cell
- Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation
- (2008) Yang Zhao et al. Cell Stem Cell
- c-Myc Is Dispensable for Direct Reprogramming of Mouse Fibroblasts
- (2008) Marius Wernig et al. Cell Stem Cell
- Sequential Expression of Pluripotency Markers during Direct Reprogramming of Mouse Somatic Cells
- (2008) Tobias Brambrink et al. Cell Stem Cell
- Reprogramming of Pancreatic β Cells into Induced Pluripotent Stem Cells
- (2008) Matthias Stadtfeld et al. CURRENT BIOLOGY
- Erratum: Dissecting direct reprogramming through integrative genomic analysis
- (2008) Tarjei S. Mikkelsen et al. NATURE
- In vivo reprogramming of adult pancreatic exocrine cells to β-cells
- (2008) Qiao Zhou et al. NATURE
- The ground state of embryonic stem cell self-renewal
- (2008) Qi-Long Ying et al. NATURE
- A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
- (2008) Marius Wernig et al. NATURE BIOTECHNOLOGY
- Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
- (2008) Danwei Huangfu et al. NATURE BIOTECHNOLOGY
- Marked differences in differentiation propensity among human embryonic stem cell lines
- (2008) Kenji Osafune et al. NATURE BIOTECHNOLOGY
- A core Klf circuitry regulates self-renewal of embryonic stem cells
- (2008) Jianming Jiang et al. NATURE CELL BIOLOGY
- Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
- (2008) M. Wernig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induced Pluripotent Stem Cells Generated Without Viral Integration
- (2008) M. Stadtfeld et al. SCIENCE
- Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
- (2008) T. Aoi et al. SCIENCE
- Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
- (2008) K. Okita et al. SCIENCE
- Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
- (2008) J. T. Dimos et al. SCIENCE
- Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition
- (2008) Jose Silva et al. PLOS BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started