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Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300

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CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions

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NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation

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Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic Opportunities

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BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia

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Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains

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CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses

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Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300

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Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

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Overexpression of GATA1 Confers Resistance to Chemotherapy in Acute Megakaryocytic Leukemia

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Genetic Screens in Human Cells Using the CRISPR-Cas9 System

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An integrated encyclopedia of DNA elements in the human genome

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MEME-ChIP: motif analysis of large DNA datasets

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Bromodomains as therapeutic targets

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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

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Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor

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Selective inhibition of BET bromodomains

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GREAT improves functional interpretation of cis-regulatory regions

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