Clusterin: Always protecting. Synthesis, function and potential issues
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Clusterin: Always protecting. Synthesis, function and potential issues
Authors
Keywords
Clusterin, Drug targeting, Biomarkers, Cytoprotection, Neuroprotection, Cardioprotective agents, Pain management, Cancer
Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 134, Issue -, Pages 111174
Publisher
Elsevier BV
Online
2020-12-24
DOI
10.1016/j.biopha.2020.111174
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Secretory clusterin promotes hepatocellular carcinoma progression by facilitating cancer stem cell properties via AKT/GSK-3β/β-catenin axis
- (2020) Wenjie Zheng et al. Journal of Translational Medicine
- CLU rs11136000 promotes early cognitive decline in Parkinson's disease
- (2020) Frederic Sampedro et al. MOVEMENT DISORDERS
- Clusterin is regulated by IGF1–PI3K signaling in the heart: implications for biomarker and drug target discovery, and cardiotoxicity
- (2020) Sebastian Bass-Stringer et al. ARCHIVES OF TOXICOLOGY
- Plasma Clusterin as a Potential Link Between Diabetes and Alzheimer Disease
- (2020) Junghee Ha et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Sciatic nerve ligation downregulates mitochondrial clusterin in the rat prefrontal cortex
- (2020) Carmen Rodríguez-Rivera et al. NEUROSCIENCE
- Clusterin Impairs Hepatic Insulin Sensitivity and Adipocyte Clusterin Associates With Cardiometabolic Risk
- (2019) David Bradley et al. DIABETES CARE
- The role of Clusterin in cancer metastasis
- (2019) Mei Peng et al. Cancer Management and Research
- Clusterin in Alzheimer’s Disease: Mechanisms, Genetics, and Lessons From Other Pathologies
- (2019) Evangeline M. Foster et al. Frontiers in Neuroscience
- Clusterin silencing restores myoblasts viability and down modulates the inflammatory process in osteoporotic disease
- (2019) S. Pucci et al. Journal of Translational Medicine
- Epithelial-Mesenchymal Plasticity in Organotropism Metastasis and Tumor Immune Escape
- (2019) Xiang Nan et al. Journal of Clinical Medicine
- Clusterin in atopic and non-atopic childhood asthma
- (2019) Ahmad Ata Sobeih et al. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
- Clusterin as a potential marker of brain ischemia-reperfusion injury in patients undergoing carotid endarterectomy
- (2019) Joanna Iłżecka et al. UPSALA JOURNAL OF MEDICAL SCIENCES
- The Multiple Roles and Therapeutic Potential of Molecular Chaperones in Prostate Cancer
- (2019) Hoter et al. Cancers
- Brain clusterin protein isoforms and mitochondrial localization
- (2019) Sarah K Herring et al. eLife
- High clusterin (CLU) mRNA expression levels in tumors of colorectal cancer patients predict a poor prognostic outcome
- (2019) Pinelopi I. Artemaki et al. CLINICAL BIOCHEMISTRY
- Clusterin ameliorates endothelial dysfunction in diabetes by suppressing mitochondrial fragmentation
- (2019) Lulu Ren et al. FREE RADICAL BIOLOGY AND MEDICINE
- Dynamics of clusterin protein expression in the brain and plasma following experimental traumatic brain injury
- (2019) Shalini Das Gupta et al. Scientific Reports
- Circuit-selective properties of glutamatergic inputs to the rat prelimbic cortex and their alterations in neuropathic pain
- (2018) Crystle J. Kelly et al. Brain Structure & Function
- Clusterin Reduces Cold Ischemia-Reperfusion Injury in Heart Transplantation Through Regulation of NF-kB Signaling and Bax/Bcl-xL Expression
- (2018) Guodong Liu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Associations of plasma clusterin and Alzheimer’s disease-related MRI markers in adults at mid-life: The CARDIA Brain MRI sub-study
- (2018) Thaddeus Haight et al. PLoS One
- Lower serum clusterin levels in patients with erosive hand osteoarthritis are associated with more pain
- (2018) Tereza Kropáčková et al. BMC MUSCULOSKELETAL DISORDERS
- Cocaine and amphetamine regulated transcript and brain-derived neurotrophic factor in morbid obesity. One-year follow-up after gastric bypass
- (2018) José Ramón Muñoz-Rodríguez et al. Surgery for Obesity and Related Diseases
- Association between clusterin concentration and dementia: a systematic review and meta-analysis
- (2018) Caiping Yang et al. METABOLIC BRAIN DISEASE
- Proteomic Identification of Biomarkers Associated with Eating Control and Bariatric Surgery Outcomes in Patients with Morbid Obesity
- (2018) Carmen Rodríguez-Rivera et al. WORLD JOURNAL OF SURGERY
- Protective molecular mechanisms of clusterin against apoptosis in cardiomyocytes
- (2017) Rodrigo Martins Pereira et al. HEART FAILURE REVIEWS
- Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial
- (2017) Tomasz M Beer et al. LANCET ONCOLOGY
- E6130, a Novel CX3C Chemokine Receptor 1 (CX3CR1) Modulator, Attenuates Mucosal Inflammation and Reduces CX3CR1 + Leukocyte Trafficking in Mice with Colitis
- (2017) Hisashi Wakita et al. MOLECULAR PHARMACOLOGY
- Role of clusterin in the brain vascular clearance of amyloid-β
- (2017) Amy R. Nelson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On the value of therapeutic interventions targeting the complement system in acute myocardial infarction
- (2017) Reindert W. Emmens et al. Translational Research
- Clusterin levels are increased in Alzheimer's disease and influence the regional distribution of Aβ
- (2016) J. Scott Miners et al. BRAIN PATHOLOGY
- Clusterin as a therapeutic target
- (2016) Mark R. Wilson et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- The epithelial–mesenchymal transition (EMT) is regulated by oncoviruses in cancer
- (2016) Xue Chen et al. FASEB JOURNAL
- Intraventricular apolipoprotein ApoJ infusion acts protectively in Traumatic Brain Injury
- (2016) Zhijian Huang et al. JOURNAL OF NEUROCHEMISTRY
- Spinal Cord Stimulation Alters Protein Levels in the Cerebrospinal Fluid of Neuropathic Pain Patients: A Proteomic Mass Spectrometric Analysis
- (2016) Anne-Li Lind et al. NEUROMODULATION
- Early Life Exposure to Undernutrition Induces ER Stress, Apoptosis, and Reduced Vascularization in Ovaries of Adult Rat Offspring1
- (2015) Kaitlyn A. Chan et al. BIOLOGY OF REPRODUCTION
- Eculizumab reduces complement activation, inflammation, endothelial damage, thrombosis, and renal injury markers in aHUS
- (2015) R. Cofiell et al. BLOOD
- Characterization of renal biomarkers for use in clinical trials: effect of preanalytical processing and qualification using samples from subjects with diabetes
- (2015) David Brott et al. Drug Design Development and Therapy
- Clusterin/ApoJ enhances central leptin signaling through Lrp2-mediated endocytosis
- (2014) K. Byun et al. EMBO REPORTS
- Molecular Profiles of Pyramidal Neurons in the Superior Temporal Cortex in Schizophrenia
- (2014) Charmaine Y. Pietersen et al. JOURNAL OF NEUROGENETICS
- Intracellular Clusterin Interacts with Brain Isoforms of the Bridging Integrator 1 and with the Microtubule-Associated Protein Tau in Alzheimer's Disease
- (2014) Yuan Zhou et al. PLoS One
- Plasma Clusterin (ApoJ) Levels Are Associated with Adiposity and Systemic Inflammation
- (2014) Jong Chul Won et al. PLoS One
- Bioactive lipids and the control of Bax pro-apoptotic activity
- (2014) V Mignard et al. Cell Death & Disease
- Glycosylation Changes in the Salivary Glycoproteins of Alcohol-Dependent Patients: A Pilot Study
- (2013) Ewa M. Kratz et al. ALCOHOL AND ALCOHOLISM
- Expression of the protein chaperone, clusterin, in spinal cord cells constitutively and following cellular stress, and upregulation by treatment with Hsp90 inhibitor
- (2013) Samantha Zinkie et al. CELL STRESS & CHAPERONES
- Correction: Non-Secreted Clusterin Isoforms Are Translated in Rare Amounts from Distinct Human mRNA Variants and Do Not Affect Bax-Mediated Apoptosis or the NF-κB Signaling Pathway
- (2013) Hans Prochnow et al. PLoS One
- Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway
- (2013) So Young Gil et al. Nature Communications
- CX3CR1 Receptor Polymorphisms, Th1 Cell Recruitment, and Acute Myocardial Infarction Outcome: Looking for a Link
- (2013) S. Pucci et al. Biomed Research International
- Proteomic Evaluation to Identify Biomarkers for Carpal Tunnel Syndrome: A Comparative Serum Analysis
- (2012) Young-Min Oh et al. CONNECTIVE TISSUE RESEARCH
- Tumor-derived secretory clusterin induces epithelial–mesenchymal transition and facilitates hepatocellular carcinoma metastasis
- (2012) Cun Wang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer
- (2012) N Li et al. ONCOGENE
- Clusterin facilitates in vivo clearance of extracellular misfolded proteins
- (2011) Amy R. Wyatt et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Semen Clusterin Is a Novel DC-SIGN Ligand
- (2011) Juan Sabatte et al. JOURNAL OF IMMUNOLOGY
- Comparative analysis of serum proteomes of degenerative scoliosis
- (2011) Yong Zhu et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Combined Proteomic and Metabolomic Profiling of Serum Reveals Association of the Complement System with Obesity and Identifies Novel Markers of Body Fat Mass Changes
- (2011) Andreas Oberbach et al. JOURNAL OF PROTEOME RESEARCH
- Phase I/II Trial of Custirsen (OGX-011), an Inhibitor of Clusterin, in Combination with a Gemcitabine and Platinum Regimen in Patients with Previously Untreated Advanced Non-small Cell Lung Cancer
- (2011) Janessa J. Laskin et al. Journal of Thoracic Oncology
- Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment
- (2011) Madhav Thambisetty et al. NEUROIMAGE
- Low Clusterin Levels in High-Density Lipoprotein Associate With Insulin Resistance, Obesity, and Dyslipoproteinemia
- (2010) Andrew N. Hoofnagle et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Randomized Phase II Study of Docetaxel and Prednisone With or Without OGX-011 in Patients With Metastatic Castration-Resistant Prostate Cancer
- (2010) Kim N. Chi et al. JOURNAL OF CLINICAL ONCOLOGY
- Clusterin silencing in human lung adenocarcinoma cells induces a mesenchymal-to-epithelial transition through modulating the ERK/Slug pathway
- (2009) Teh-Ying Chou et al. CELLULAR SIGNALLING
- Identification and characterization of glycosylation sites in human serum clusterin
- (2009) James T. Kapron et al. PROTEIN SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation