Protective molecular mechanisms of clusterin against apoptosis in cardiomyocytes

Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes

(2016) Vadim N. Gladyshev   AGING CELL

Cytosolic Ku70 regulates Bax-mediated cell death

(2016) Manila Hada et al.   TUMOR BIOLOGY

Exosomal clusterin, identified in the pericardial fluid, improves myocardial performance following MI through epicardial activation, enhanced arteriogenesis and reduced apoptosis

(2015) Eleonora Foglio et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Apolipoprotein-J prevents angiotensin II-induced apoptosis in neonatal rat ventricular cells

(2015) Yanzhuo Ma et al.   Lipids in Health and Disease

Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer

(2015) Kenneth Alibek et al.   Infectious Agents and Cancer

Secretory clusterin is upregulated in rats with pulmonary arterial hypertension induced by systemic-to-pulmonary shunts and exerts important roles in pulmonary artery smooth muscle cells

(2014) X. Liu et al.   Acta Physiologica

Exercise training enhanced SIRT1 longevity signaling replaces the IGF1 survival pathway to attenuate aging-induced rat heart apoptosis

(2014) Chao-Hung Lai et al.   AGE

Ageing related periostin expression increase from cardiac fibroblasts promotes cardiomyocytes senescent

(2014) Qing Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Secreted Clusterin Gene Silencing Enhances Chemosensitivity of A549 Cells to Cisplatin Through AKT and ERK1/2 Pathwaysin Vitro

(2014) Biyuan Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Deficiency of Clusterin Exacerbates High-Fat Diet-Induced Insulin Resistance in Male Mice

(2014) Min Jung Kwon et al.   ENDOCRINOLOGY

Proteomic biomarkers of recovered heart function

(2014) Zsuzsanna Hollander et al.   EUROPEAN JOURNAL OF HEART FAILURE

Many players in BCL-2 family affairs

(2014) Tudor Moldoveanu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Periostin in Allergic Inflammation

(2014) Kenji Izuhara et al.   ALLERGOLOGY INTERNATIONAL

The Molecular Chaperone Apolipoprotein J/Clusterin as a Sensor of Oxidative Stress: Implications in Therapeutic Approaches - A Mini-Review

(2013) Ioannis P. Trougakos   GERONTOLOGY

Stable Knockdown of Clusterin by Vector-Based RNA Interference in a Human Breast Cancer Cell Line Inhibits Tumour Cell Invasion and Metastasis

(2013) J Li et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Knockdown of clusterin inhibits the growth and migration of renal carcinoma cells and leads to differential gene expression

(2013) HUA SHI et al.   Molecular Medicine Reports

The physiological roles of apolipoprotein J/clusterin in metabolic and cardiovascular diseases

(2013) S. Park et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Distinct profiles of oxidative stress–related and matrix proteins in adult bone and soft tissue osteosarcoma and desmoid tumors: A proteomics study

(2012) Uma N.M. Rao et al.   HUMAN PATHOLOGY

IGF-1 activates the P13K/AKT signaling pathway via upregulation of secretory clusterin

(2012) XIUMEI MA et al.   Molecular Medicine Reports

Is Physical Activity Able to Modify Oxidative Damage in Cardiovascular Aging?

(2012) Graziamaria Corbi et al.   Oxidative Medicine and Cellular Longevity

Clusterin protects H9c2 cardiomyocytes from oxidative stress-induced apoptosisviaAkt/GSK-3β signaling pathway

(2011) Hyoung-Oh Jun et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Reduction of cold ischemia–reperfusion injury by graft-expressing clusterin in heart transplantation

(2011) Shuyuan Li et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Types of Cardiomyocyte Death and Clinical Outcomes in Patients With Heart Failure⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology

(2011) Sawa Kostin   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiomyocyte death: mechanisms and translational implications

(2011) M Chiong et al.   Cell Death & Disease

Ageing-induced decline in physical endurance in mice is associated with decrease in cardiac SUR2A and increase in cardiac susceptibility to metabolic stress: therapeutic prospects for up-regulation of SUR2A

(2010) Rajni Sudhir et al.   BIOGERONTOLOGY

Intravenous clusterin administration reduces myocardial infarct size in rats

(2010) Annemieke Van Dijk et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Clusterin induces CXCR4 expression and migration of cardiac progenitor cells

(2010) Yangxin Li et al.   EXPERIMENTAL CELL RESEARCH

Protein Therapeutics for Cardiac Regeneration after Myocardial Infarction

(2010) Vincent F. M. Segers et al.   Journal of Cardiovascular Translational Research

Role of apoptosis in cardiovascular disease

(2009) Youngil Lee et al.   APOPTOSIS

Cell death induced by zinc and cadmium is mediated by clusterin in cultured mouse seminiferous tubules

(2009) Tehila Kaisman-Elbaz et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intracellular Clusterin Inhibits Mitochondrial Apoptosis by Suppressing p53-Activating Stress Signals and Stabilizing the Cytosolic Ku70-Bax Protein Complex

(2008) I. P. Trougakos et al.   CLINICAL CANCER RESEARCH

Clusterin expression predicts survival of invasive cervical cancer patients treated with radical hysterectomy and systematic lymphadenectomy

(2008) Hidemichi Watari et al.   GYNECOLOGIC ONCOLOGY

Clusterin Activates Survival through the Phosphatidylinositol 3-Kinase/Akt Pathway

(2008) Hayet Ammar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY