Cholesterol, lipoproteins, and COVID-19: Basic concepts and clinical applications

Recent insights into 2019-nCoV: a brief but comprehensive review

(2020) Qingmei Han et al.   JOURNAL OF INFECTION

Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS‐CoV, MERS‐CoV, and 2019‐nCoV

(2020) Jia Liu et al.   JOURNAL OF MEDICAL VIROLOGY

Emerging coronaviruses: Genome structure, replication, and pathogenesis

(2020) Yu Chen et al.   JOURNAL OF MEDICAL VIROLOGY

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa

(2020) Hao Xu et al.   International Journal of Oral Science

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

(2020) Hin Chu et al.   CLINICAL INFECTIOUS DISEASES

ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19

(2020) Rhian M. Touyz et al.   CLINICAL SCIENCE

Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

(2020) Daniel Batlle et al.   CLINICAL SCIENCE

The lysosome: A potential juncture between SARS‐CoV‐2 infectivity and Niemann‐Pick disease type C, with therapeutic implications

(2020) Rami A. Ballout et al.   FASEB JOURNAL

The Role of Lipid Metabolism in COVID-19 Virus Infection and as a Drug Target

(2020) Mohamed Abu-Farha et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypolipidemia is associated with the severity of COVID-19

(2020) Xiuqi Wei et al.   Journal of Clinical Lipidology

Familial hypercholesterolaemia and COVID‐19: triggering of increased sustained cardiovascular risk

(2020) Alpo Vuorio et al.   JOURNAL OF INTERNAL MEDICINE

Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19)

(2020) Dae-Gyun Ahn et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Are certain drugs associated with enhanced mortality in COVID-19?

(2020) M R Goldstein et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

(2020) Xiuyuan Ou et al.   Nature Communications

Drugs and the renin-angiotensin system in covid-19

(2020) Jeffrey K Aronson et al.   BMJ-British Medical Journal

Coronavirus Disease 2019 (COVID‐19): Do Angiotensin‐Converting Enzyme Inhibitors/Angiotensin Receptor Blockers Have a Biphasic Effect?

(2020) Rami Sommerstein et al.   Journal of the American Heart Association

High-Density Lipoproteins Are Bug Scavengers

(2020) Olivier Meilhac et al.   Biomolecules

Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic

(2020) Maciej Banach et al.   PHARMACOLOGICAL RESEARCH

Cytokine Storm in COVID-19—Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper

(2020) Sonu Bhaskar et al.   Frontiers in Immunology

THE CHOLESTEROL METABOLITE 27-HYDROXYCHOLESTEROL INHIBITS SARS-CoV-2 AND IS MARKEDLY DECREASED IN COVID-19 PATIENTS

(2020) Alessandro Marcello et al.   Redox Biology

Cholesterol in Relation to COVID-19: Should We Care about It?

(2020) Dina Radenkovic et al.   Journal of Clinical Medicine

Interaction Between Coronavirus S-Protein and Human ACE2: Hints for Exploring Efficient Therapeutic Targets to Treat COVID-19

(2020) Amir Abbas Momtazi-Borojeni et al.   ANGIOLOGY

Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis

(2019) Eugenia Marbach-Breitrück et al.   JOURNAL OF HEPATOLOGY

Human T lymphotropic virus type 1 and risk of cardiovascular disease: High-density lipoprotein dysfunction versus serum HDL-C concentrations

(2019) Sara Samadi et al.   BIOFACTORS

Virion-Associated Cholesterol Regulates the Infection of Human Parainfluenza Virus Type 3

(2019) Qiaopeng Tang et al.   Viruses-Basel

Nuclear receptors, cholesterol homeostasis and the immune system

(2019) Sayyed Hamed Shahoei et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

SLC10A1 S267F variant influences susceptibility to HBV infection and reduces cholesterol level by impairing bile acid uptake

(2019) Xiang Cheng et al.   JOURNAL OF VIRAL HEPATITIS

Oxysterols and Gastrointestinal Cancers Around the Clock

(2019) Urša Kovač et al.   Frontiers in Endocrinology

The lipid membrane of HIV-1 stabilizes the viral envelope glycoproteins and modulates their sensitivity to antibody neutralization

(2019) Hamid Salimi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Cholesterol Modulates Oligomeric Status and Peptide-Membrane Interaction of Severe Acute Respiratory Syndrome Coronavirus Fusion Peptide

(2019) Geetanjali Meher et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Mechanisms and regulation of cholesterol homeostasis

(2019) Jie Luo et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Personalized therapy when tackling nonalcoholic fatty liver disease: a focus on sex, genes, and drugs

(2018) Cene Skubic et al.   Expert Opinion on Drug Metabolism & Toxicology

Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function

(2018) Wen-Jun Shen et al.   JOURNAL OF LIPID RESEARCH

Associations of gender and serum total cholesterol with CD4+ T cell count and HIV RNA load in antiretroviral-naïve individuals in Addis Ababa

(2018) Melaku Adal et al.   BMC PUBLIC HEALTH

Pharmacogenomic and personalized approaches to tackle nonalcoholic fatty liver disease

(2016) Gregor Lorbek et al.   PHARMACOGENOMICS

Lessons from Hepatocyte-Specific Cyp51 Knockout Mice: Impaired Cholesterol Synthesis Leads to Oval Cell-Driven Liver Injury

(2015) Gregor Lorbek et al.   Scientific Reports

From Nonalcoholic Fatty Liver Disease to Hepatocellular Carcinoma: A Systems Understanding

(2014) Damjana Rozman   DIGESTIVE DISEASES AND SCIENCES

Pathogenesis of Middle East respiratory syndrome coronavirus

(2014) Judith MA van den Brand et al.   JOURNAL OF PATHOLOGY

Hidden Disease Susceptibility and Sexual Dimorphism in the Heterozygous Knockout of Cyp51 from Cholesterol Synthesis

(2014) Monika Lewinska et al.   PLoS One

Innate Immune Response of Human Alveolar Type II Cells Infected with Severe Acute Respiratory Syndrome–Coronavirus

(2013) Zhaohui Qian et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Tropism of and Innate Immune Responses to the Novel Human Betacoronavirus Lineage C Virus in Human Ex Vivo Respiratory Organ Cultures

(2013) R. W. Y. Chan et al.   JOURNAL OF VIROLOGY

Steroidal Triterpenes of Cholesterol Synthesis

(2013) Jure Ačimovič et al.   MOLECULES

Molecular Interactions between NAFLD and Xenobiotic Metabolism

(2013) Adviti Naik et al.   Frontiers in Genetics

The Interplay between Circadian System, Cholesterol Synthesis, and Steroidogenesis Affects Various Aspects of Female Reproduction

(2013) Ziga Urlep et al.   Frontiers in Endocrinology

Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol

(2012) Su-Yang Liu et al.   IMMUNITY

Dysfunctional HDL: A novel important diagnostic and therapeutic target in cardiovascular disease?

(2012) Aneta Otocka-Kmiecik et al.   PROGRESS IN LIPID RESEARCH

Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments

(2011) Simon Horvat et al.   DRUG METABOLISM REVIEWS

The human primary hepatocyte transcriptome reveals novel insights into atorvastatin and rosuvastatin action

(2011) Mateja Hafner et al.   Pharmacogenetics and Genomics

Interplay between cholesterol and drug metabolism

(2010) Tadeja Rezen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Changes in HDL-associated apolipoproteins relate to mortality in human sepsis and correlate to monocyte and platelet activation

(2009) Stefan Barlage et al.   INTENSIVE CARE MEDICINE

Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2

(2008) Joerg Glende et al.   VIROLOGY