Type-2 diabetes, a co-morbidity in Covid-19: does insulin signaling matter?

Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations

(2020) Yanan Cao et al.   Cell Discovery

COVID-19 pandemic, coronaviruses, and diabetes mellitus

(2020) Ranganath Muniyappa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Remdesivir attenuates high fat diet (HFD)-induced NAFLD by regulating hepatocyte dyslipidemia and inflammation via the suppression of STING

(2020) Yan-Ni Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System

(2020) Mahmoud Gheblawi et al.   CIRCULATION RESEARCH

COVID-19 cytokine storm: The anger of inflammation

(2020) Mehdi Mahmudpour et al.   CYTOKINE

Exploring Diseases/Traits and Blood Proteins Causally Related to Expression of ACE2, the Putative Receptor of SARS-CoV-2: A Mendelian Randomization Analysis Highlights Tentative Relevance of Diabetes-Related Traits

(2020) Shitao Rao et al.   DIABETES CARE

Diabetes is a risk factor for the progression and prognosis of COVID-19

(2020) Weina Guo et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

COVID-19 and the role of chronic inflammation in patients with obesity

(2020) Sonja Chiappetta et al.   INTERNATIONAL JOURNAL OF OBESITY

Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy

(2020) Graziano Onder et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is likely to be androgen mediated

(2020) Carlos Gustavo Wambier et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Expression of angiotensin-converting enzyme 2 and proteases in COVID-19 patients: a potential role of cellular FURIN in the pathogenesis of SARS-CoV-2

(2020) Kinan Drak Alsibai   MEDICAL HYPOTHESES

Coronavirus Disease 2019 (COVID‐19): Do Angiotensin‐Converting Enzyme Inhibitors/Angiotensin Receptor Blockers Have a Biphasic Effect?

(2020) Rami Sommerstein et al.   Journal of the American Heart Association

COVID-19 and Diabetes Mellitus: May Old Anti-diabetic Agents Become the New Philosopher’s Stone?

(2020) Theano Penlioglou et al.   Diabetes Therapy

The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular Disease

(2020) Majd AlGhatrif et al.   JAMA Cardiology

Metformin in COVID-19: A possible role beyond diabetes

(2020) Swati Sharma et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The Another Side of COVID‐19 in Alzheimer’s Disease Patients: Drug‐Drug Interactions

(2020) Nisa Balli et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Potential Novel Role of COVID-19 in Alzheimer’s Disease and Preventative Mitigation Strategies

(2020) Sean X. Naughton et al.   JOURNAL OF ALZHEIMERS DISEASE

New-Onset Diabetes in Covid-19

(2020) Francesco Rubino et al.   NEW ENGLAND JOURNAL OF MEDICINE

COVID-19 in people with diabetes: understanding the reasons for worse outcomes

(2020) Matteo Apicella et al.   Lancet Diabetes & Endocrinology

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells

(2020) Katie C. Coate et al.   Cell Metabolism

Loss of Furin in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction

(2020) Bas Brouwers et al.   DIABETES

Protein Kinase C Attenuates Insulin Signalling Cascade in Insulin-Sensitive and Insulin-Resistant Neuro-2a Cells

(2019) Devanshi Mishra et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality

(2018) C. Fernandez et al.   JOURNAL OF INTERNAL MEDICINE

Insulin Resistance in Alzheimer's Disease

(2018) Laís S. S. Ferreira et al.   Frontiers in Neuroscience

Hyperglycemia Promotes TMPRSS2-ERG Gene Fusion in Prostate Cancer Cells via Upregulating Insulin-Like Growth Factor-Binding Protein-2

(2017) Jeff M. P. Holly et al.   Frontiers in Endocrinology

SIRT2 regulates insulin sensitivity in insulin resistant neuronal cells

(2016) Amita Arora et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

P21-activated kinase 2 (PAK2) regulates glucose uptake and insulin sensitivity in neuronal cells

(2016) Pallavi Varshney et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

High Efficacy of Combination Therapy Using PI3K/AKT Inhibitors with Androgen Deprivation in Prostate Cancer Preclinical Models

(2015) Rute B. Marques et al.   EUROPEAN UROLOGY

SIRT2 negatively regulates insulin resistance in C2C12 skeletal muscle cells

(2014) Amita Arora et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Pioglitazone Upregulates Angiotensin Converting Enzyme 2 Expression in Insulin-Sensitive Tissues in Rats with High-Fat Diet-Induced Nonalcoholic Steatohepatitis

(2014) Wei Zhang et al.   TheScientificWorldJOURNAL

Focal adhesion kinase negatively regulates neuronal insulin resistance

(2012) Amit Gupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Loss of ACE2 Exaggerates High-Calorie Diet–Induced Insulin Resistance by Reduction of GLUT4 in Mice

(2012) Masao Takeda et al.   DIABETES

The Role of Glucose Transporters in Brain Disease: Diabetes and Alzheimer's Disease

(2012) Kaushik Shah et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance

(2012) Amit Gupta et al.   MOLECULAR BIOLOGY OF THE CELL

Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer’s-like changes

(2011) Amit Gupta et al.   NEUROPHARMACOLOGY

PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase☆

(2009) Amit Gupta et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease

(2008) Wei-Qin Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

In vivoinhibition of focal adhesion kinase causes insulin resistance

(2008) Bharti Bisht et al.   JOURNAL OF PHYSIOLOGY-LONDON