Neutrophil Extracellular Traps as Prognostic Markers in COVID-19

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

(2020) Franziska Herster et al.   Nature Communications

Animal models of mechanisms of SARS‐CoV‐2 infection and COVID‐19 pathology

(2020) Simon J. Cleary et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neutrophil Extracellular Traps Participate in Cardiovascular Diseases

(2020) Yvonne Döring et al.   CIRCULATION RESEARCH

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

(2020) Betsy J. Barnes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Histones, DNA, and Citrullination Promote Neutrophil Extracellular Trap Inflammation by Regulating the Localization and Activation of TLR4

(2020) Theodora-Dorita Tsourouktsoglou et al.   Cell Reports

Coagulation Abnormalities and Thrombosis in Patients Infected With SARS-CoV-2 and Other Pandemic Viruses

(2020) Nigel Mackman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 Acute Respiratory Distress Syndrome

(2020) Elizabeth A Middleton et al.   BLOOD

DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25

(2020) Linbin Yang et al.   NATURE

Prothrombotic fibrin clot properties associated with NETs formation characterize acute pulmonary embolism patients with higher mortality risk

(2020) Michał Ząbczyk et al.   Scientific Reports

Vascular occlusion by neutrophil extracellular traps in COVID-19

(2020) Moritz Leppkes et al.   EBioMedicine

COVID-19 length of hospital stay: a systematic review and data synthesis

(2020) Eleanor M. Rees et al.   BMC Medicine

Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

(2020) Panagiotis Skendros et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19

(2020) Coraline Radermecker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

(2020) Flavio Protasio Veras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Animal models for COVID-19

(2020) César Muñoz-Fontela et al.   NATURE

Novel contributions of neutrophils in the pathogenesis of abdominal aortic aneurysm, the role of neutrophil extracellular traps: A systematic review

(2020) Emma Plana et al.   THROMBOSIS RESEARCH

The Emerging Role of Neutrophil Extracellular Traps (NETs) in Tumor Progression and Metastasis

(2020) Maria Teresa Masucci et al.   Frontiers in Immunology

Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19

(2020) Henry Ng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Neutrophil Extracellular Traps Are Elevated in Patients with Pneumonia-related Acute Respiratory Distress Syndrome

(2019) Inès Bendib et al.   ANESTHESIOLOGY

Critical role of neutrophil extracellular traps (NETs) in patients with Behcet’s disease

(2019) Alexandre Le Joncour et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil extracellular traps and fibrocytes in ST-segment elevation myocardial infarction

(2019) Thomas M. Hofbauer et al.   BASIC RESEARCH IN CARDIOLOGY

Circulating neutrophil and eosinophil extracellular traps are markers of severe asthma

(2019) Vanessa Granger et al.   ALLERGY

Extracellular DNA NET-Works With Dire Consequences for Health

(2019) Nicoletta Sorvillo et al.   CIRCULATION RESEARCH

Neutrophil extracellular traps drive inflammatory pathogenesis in malaria

(2019) Sebastian Lorenz Knackstedt et al.   Science Immunology

REDD1/Autophagy Pathway Is Associated with Neutrophil-Driven IL-1β Inflammatory Response in Active Ulcerative Colitis

(2018) Iliana Angelidou et al.   JOURNAL OF IMMUNOLOGY

Neutrophil extracellular traps in fungal infection

(2018) Constantin F. Urban et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases

(2018) Jonas Hahn et al.   FASEB JOURNAL

The state of art of neutrophil extracellular traps in protozoan and helminthic infections

(2018) César Díaz-Godínez et al.   BIOSCIENCE REPORTS

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

Host DNases prevent vascular occlusion by neutrophil extracellular traps

(2017) Miguel Jiménez-Alcázar et al.   SCIENCE

Degradation of Extracellular DNA by DNase1 Significantly Reduces Testicular Damage After Testicular Torsion in Rats

(2017) Michael Boettcher et al.   UROLOGY

Understanding the Entanglement: Neutrophil Extracellular Traps (NETs) in Cystic Fibrosis

(2017) Saira R. Martínez-Alemán et al.   Frontiers in Cellular and Infection Microbiology

Oxidized LDL induced extracellular trap formation in human neutrophils via TLR-PKC-IRAK-MAPK and NADPH-oxidase activation

(2016) Deepika Awasthi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Peptidylarginine deiminase 4 promotes age-related organ fibrosis

(2016) Kimberly Martinod et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Extracellular Traps Go Viral

(2016) Günther Schönrich et al.   Frontiers in Immunology

Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction

(2015) Dimitrios A. Stakos et al.   EUROPEAN HEART JOURNAL

Neutrophil extracellular traps regulate IL-1β-mediated inflammation in familial Mediterranean fever

(2014) Eirini Apostolidou et al.   ANNALS OF THE RHEUMATIC DISEASES

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Pulmonary retention of primed neutrophils: a novel protective host response, which is impaired in the acute respiratory distress syndrome

(2014) Charlotte Summers et al.   THORAX

Citrullination of autoantigens implicates NETosis in the induction of autoimmunity

(2013) Nishant Dwivedi et al.   ANNALS OF THE RHEUMATIC DISEASES

Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence

(2013) E. Sapey et al.   BLOOD

Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow

(2013) Sapna Devi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice

(2012) G. M. Thomas et al.   BLOOD

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury

(2012) Axelle Caudrillier et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease

(2012) J. Leffler et al.   JOURNAL OF IMMUNOLOGY

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

(2012) Mona Saffarzadeh et al.   PLoS One

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

(2011) Q Remijsen et al.   CELL DEATH AND DIFFERENTIATION

Neutrophil extracellular traps promote deep vein thrombosis in mice

(2011) A. BRILL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA