Animal models for COVID-19

Transcriptional Correlates of Tolerance and Lethality in Mice Predict Ebola Virus Disease Patient Outcomes

(2020) Adam Price et al.   Cell Reports

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Infection and Rapid Transmission of SARS-CoV-2 in Ferrets

(2020) Young-Il Kim et al.   Cell Host & Microbe

A Mouse Model of SARS-CoV-2 Infection and Pathogenesis

(2020) Shi-Hui Sun et al.   Cell Host & Microbe

Comparison of SARS-CoV-2 spike protein binding to ACE2 receptors from human, pets, farm animals, and putative intermediate hosts

(2020) Xiaofeng Zhai et al.   JOURNAL OF VIROLOGY

Pathogenesis and transmission of SARS-CoV-2 in golden hamsters

(2020) Sin Fun Sia et al.   NATURE

Labs rush to study coronavirus in transgenic animals — some are in short supply

(2020) Ewen Callaway   NATURE

Respiratory disease in rhesus macaques inoculated with SARS-CoV-2

(2020) Vincent J. Munster et al.   NATURE

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

(2020) Linlin Bao et al.   NATURE

The pandemic pipeline

(2020) John Hodgson   NATURE BIOTECHNOLOGY

The proximal origin of SARS-CoV-2

(2020) Kristian G. Andersen et al.   NATURE MEDICINE

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transmission of SARS-CoV-2 in Domestic Cats

(2020) Peter J. Halfmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

(2020) Abishek Chandrashekar et al.   SCIENCE

Rapid COVID-19 vaccine development

(2020) Barney S. Graham   SCIENCE

Development of an inactivated vaccine candidate for SARS-CoV-2

(2020) Qiang Gao et al.   SCIENCE

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2

(2020) Jianzhong Shi et al.   SCIENCE

DNA vaccine protection against SARS-CoV-2 in rhesus macaques

(2020) Jingyou Yu et al.   SCIENCE

Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

(2020) Barry Rockx et al.   SCIENCE

Supporting pandemic response using genomics and bioinformatics: A case study on the emergent SARS‐CoV‐2 outbreak

(2020) Denis C. Bauer et al.   Transboundary and Emerging Diseases

The hallmarks of COVID-19 disease

(2020) Daolin Tang et al.   PLoS Pathogens

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

(2020) Ahmed O. Hassan et al.   CELL

SARS-CoV-2 infection in farmed minks, the Netherlands, April and May 2020

(2020) Nadia Oreshkova et al.   Eurosurveillance

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

(2020) Benjamin Israelow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Estimates of the severity of coronavirus disease 2019: a model-based analysis

(2020) Robert Verity et al.   LANCET INFECTIOUS DISEASES

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

(2020) Brandi N. Williamson et al.   NATURE

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

(2020) Noe B. Mercado et al.   NATURE

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

(2020) Neeltje van Doremalen et al.   NATURE

Multisystem Inflammatory Syndrome in U.S. Children and Adolescents

(2020) Leora R. Feldstein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

(2020) Kizzmekia S. Corbett et al.   NEW ENGLAND JOURNAL OF MEDICINE

Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility

(2020) Hong-Long Ji et al.   PHYSIOLOGICAL REVIEWS

Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters

(2020) Nikolaus Osterrieder et al.   Viruses-Basel

A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

(2020) Kenneth H. Dinnon et al.   NATURE

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

(2020) Joana Damas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Syrian Hamster as an Animal Model for the Study on Infectious Diseases

(2019) Jinxin Miao et al.   Frontiers in Immunology

Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin

(2018) Peng Zhou et al.   NATURE

SARS-Like Coronavirus WIV1-CoV Does Not Replicate in Egyptian Fruit Bats (Rousettus aegyptiacus)

(2018) Neeltje van Doremalen et al.   Viruses-Basel

Severity of Disease in Humanized Mice Infected With Ebola Virus or Reston Virus Is Associated With Magnitude of Early Viral Replication in Liver

(2017) Jessica R Spengler et al.   JOURNAL OF INFECTIOUS DISEASES

Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice

(2017) Kun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-like WIV1-CoV poised for human emergence

(2016) Vineet D. Menachery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

(2016) Adam S. Cockrell et al.   Nature Microbiology

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

(2015) Vineet D Menachery et al.   NATURE MEDICINE

Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

(2015) Kristen E. Pascal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferret models of viral pathogenesis

(2015) T. Enkirch et al.   VIROLOGY

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross

(2015) Lisa E. Gralinski et al.   PLoS Genetics

Rapid generation of a mouse model for Middle East respiratory syndrome

(2014) Jincun Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

(2014) A. L. Rasmussen et al.   SCIENCE

Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing

(2013) N. Frias-Staheli et al.   JOURNAL OF VIROLOGY

Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2

(2008) J. Netland et al.   JOURNAL OF VIROLOGY

A review of studies on animal reservoirs of the SARS coronavirus

(2007) Zhengli Shi et al.   VIRUS RESEARCH