Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice

Maea expressed by macrophages, but not erythroblasts, maintains postnatal murine bone marrow erythroblastic islands

(2019) Qiaozhi Wei et al.   BLOOD

Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis

(2019) Nadine Müller-Calleja et al.   BLOOD

Myeloid cell–synthesized coagulation factor X dampens antitumor immunity

(2019) Claudine Graf et al.   Science Immunology

Extravascular coagulation in hematopoietic stem and progenitor cell regulation

(2018) T. Son Nguyen et al.   BLOOD

Protease-Activated Receptor-2 Plays a Critical Role in Vascular Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice

(2018) Tomoya Hara et al.   CIRCULATION

The hematopoietic stem cell niche: from embryo to adult

(2018) Xin Gao et al.   DEVELOPMENT

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

(2018) Charlotte L. Scott et al.   IMMUNITY

Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance

(2018) Devram S. Ghorpade et al.   NATURE

Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature

(2017) Tomoko Yamazaki et al.   Cell Reports

Interaction of the Macrophage and Primitive Erythroid Lineages in the Mammalian Embryo

(2017) James Palis   Frontiers in Immunology

Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice

(2017) Yicong Liu et al.   Scientific Reports

Matriptase activation connects tissue factor-dependent coagulation initiation to epithelial proteolysis and signaling

(2016) S. M. Le Gall et al.   BLOOD

Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance

(2016) Bangwei Luo et al.   IMMUNITY

New insights into the multidimensional concept of macrophage ontogeny, activation and function

(2016) Florent Ginhoux et al.   NATURE IMMUNOLOGY

Origin, fate and dynamics of macrophages at central nervous system interfaces

(2016) Tobias Goldmann et al.   NATURE IMMUNOLOGY

Specification of tissue-resident macrophages during organogenesis

(2016) E. Mass et al.   SCIENCE

Hematopoietic Tissue Factor–Protease-Activated Receptor 2 Signaling Promotes Hepatic Inflammation and Contributes to Pathways of Gluconeogenesis and Steatosis in Obese Mice

(2015) Jing Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Macrophages and iron trafficking at the birth and death of red cells

(2015) T. Korolnek et al.   BLOOD

Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice

(2015) H. P. H. Liang et al.   BLOOD

EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice

(2015) Hai Po H. Liang et al.   BLOOD

PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells

(2015) Shiri Gur-Cohen et al.   NATURE MEDICINE

Multiple roles of the coagulation protease cascade during virus infection

(2014) S. Antoniak et al.   BLOOD

Regulation of Feto-Maternal Barrier by Matriptase- and PAR-2-Mediated Signaling Is Required for Placental Morphogenesis and Mouse Embryonic Survival

(2014) Roman Szabo et al.   PLoS Genetics

Primitive and definitive erythropoiesis in mammals

(2014) James Palis   Frontiers in Physiology

Transactivation of the PAR1-PAR2 Heterodimer by Thrombin Elicits β-Arrestin-mediated Endosomal Signaling

(2013) Huilan Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The embryonic origins of erythropoiesis in mammals

(2012) M. H. Baron et al.   BLOOD

Development of membrane mechanical function during terminal stages of primitive erythropoiesis in mice

(2012) Richard E. Waugh et al.   EXPERIMENTAL HEMATOLOGY

Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity

(2012) Hartmut Geiger et al.   NATURE MEDICINE

Protease-Activated Receptor-2 Modulates Protease-Activated Receptor-1–Driven Neointimal Hyperplasia

(2011) Leila M. Sevigny et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A transient definitive erythroid lineage with unique regulation of the  -globin locus in the mammalian embryo

(2011) K. E. McGrath et al.   BLOOD

Proteinase-activated receptor 2 activation promotes an anti-inflammatory and alternatively activated phenotype in LPS-stimulated murine macrophages

(2011) Quan M Nhu et al.   Innate Immunity

Tissue factor–protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation

(2011) Leylla Badeanlou et al.   NATURE MEDICINE

Protease-activated receptor 2 signaling in inflammation

(2011) Andrea S. Rothmeier et al.   Seminars in Immunopathology

Local Protease Signaling Contributes to Neural Tube Closure in the Mouse Embryo

(2010) Eric Camerer et al.   DEVELOPMENTAL CELL

The Endothelial Protein C Receptor Supports Tissue Factor Ternary Coagulation Initiation Complex Signaling through Protease-activated Receptors

(2010) Jennifer Disse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TAM receptors and the regulation of erythropoiesis in mice

(2009) H. Tang et al.   HAEMATOLOGICA

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

(2009) Noelia A-Gonzalez et al.   IMMUNITY

Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cell activation in vivo

(2009) Giancarlo Ramelli et al.   IMMUNOLOGY

Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo

(2009) Q M Nhu et al.   Mucosal Immunology

IFN regulatory factor (IRF) 3/7-dependent and -independent gene induction by mammalian DNA that escapes degradation

(2008) Yasutaka Okabe et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Analysis of Proteinase-activated Receptor 2 and TLR4 Signal Transduction

(2008) Prasad Rallabhandi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of PAR2 in murine pulmonary pseudomonal infection

(2007) Theo J. Moraes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY