PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells

Activated protein C: biased for translation

(2015) J. H. Griffin et al.   BLOOD

Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis

(2015) L. Pepler et al.   BLOOD

Thrombin receptor deficiency leads to a high bone mass phenotype by decreasing the RANKL/OPG ratio

(2015) Kukiat Tudpor et al.   BONE

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

(2015) Nicola K. Wilson et al.   Cell Stem Cell

Identification of multipotent mammary stem cells by protein C receptor expression

(2014) Daisong Wang et al.   NATURE

Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells

(2014) Meng Zhao et al.   NATURE MEDICINE

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion

(2014) Ingmar Bruns et al.   NATURE MEDICINE

A novel role for factor VIII and thrombin/PAR1 in regulating hematopoiesis and its interplay with the bone structure

(2013) A. Aronovich et al.   BLOOD

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

(2013) Alejandra Sanjuan-Pla et al.   NATURE

Endothelial Protein C Receptor Function in Murine and Human Breast Cancer Development

(2013) Florence Schaffner et al.   PLoS One

Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated β1/β2-integrin trafficking

(2013) E. Taniguchi Ishikawa et al.   Nature Communications

Cdc42 Activity Regulates Hematopoietic Stem Cell Aging and Rejuvenation

(2012) Maria Carolina Florian et al.   Cell Stem Cell

Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow

(2012) Aya Ludin et al.   NATURE IMMUNOLOGY

Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity

(2012) Hartmut Geiger et al.   NATURE MEDICINE

A blood flow-dependent klf2a-NO signaling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos

(2011) L. Wang et al.   BLOOD

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

(2011) A Dar et al.   LEUKEMIA

CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions

(2011) Amir Schajnovitz et al.   NATURE IMMUNOLOGY

eNOS phosphorylation in health and disease

(2010) Gopi Krishna Kolluru et al.   BIOCHIMIE

Endothelial protein C receptor-expressing hematopoietic stem cells reside in the perisinusoidal niche in fetal liver

(2010) H. Iwasaki et al.   BLOOD

The Endothelial Protein C Receptor Supports Tissue Factor Ternary Coagulation Initiation Complex Signaling through Protease-activated Receptors

(2010) Jennifer Disse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential

(2009) D. G. Kent et al.   BLOOD

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

(2009) Trista E. North et al.   CELL

Endogenous activated protein C signaling is critical to protection of mice from lipopolysaccaride-induced septic shock

(2009) J. XU et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Biomechanical forces promote embryonic haematopoiesis

(2009) Luigi Adamo et al.   NATURE

Matrix Metalloproteinase 1 Is Necessary for the Migration of Human Bone Marrow-Derived Mesenchymal Stem Cells Toward Human Glioma

(2009) Ivy A. W. Ho et al.   STEM CELLS

Stem-cell ecology and stem cells in motion

(2008) T. Papayannopoulou et al.   BLOOD

Stem Cell Regulation via Dynamic Interactions of the Nervous and Immune Systems with the Microenvironment

(2008) Asaf Spiegel et al.   Cell Stem Cell

Haematopoietic stem cell release is regulated by circadian oscillations

(2008) Simón Méndez-Ferrer et al.   NATURE