Multiple roles of the coagulation protease cascade during virus infection

Agonists of Proteinase-Activated Receptor-2 Enhance IFN- -Inducible Effects on Human Monocytes: Role in Influenza A Infection

(2014) M. Feld et al.   JOURNAL OF IMMUNOLOGY

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

Switch from protective to adverse inflammation during influenza: viral determinants and hemostasis are caught as culprits

(2013) Fatma Berri et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells

(2013) E. M. Gleeson et al.   HAEMATOLOGICA

PAR-1 contributes to the innate immune response during viral infection

(2013) Silvio Antoniak et al.   JOURNAL OF CLINICAL INVESTIGATION

The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase

(2013) Y. Xing et al.   JOURNAL OF GENERAL VIROLOGY

Protease-Activated Receptor-2 Regulates the Innate Immune Response to Viral Infection in a Coxsackievirus B3–Induced Myocarditis

(2013) Alice Weithauser et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

(2013) Zhili Xu et al.   NATURE MEDICINE

Modulation of Protease Activated Receptor 1 Influences Human Metapneumovirus Disease Severity in a Mouse Model

(2013) Laetitia Aerts et al.   PLoS One

Coagulation, Protease-Activated Receptors, and Viral Myocarditis

(2013) Silvio Antoniak et al.   Journal of Cardiovascular Translational Research

Plasminogen Controls Inflammation and Pathogenesis of Influenza Virus Infections via Fibrinolysis

(2013) Fatma Berri et al.   PLoS Pathogens

HIV Replication Alters the Composition of Extrinsic Pathway Coagulation Factors and Increases Thrombin Generation

(2013) Jason V. Baker et al.   Journal of the American Heart Association

The Economic Burden of Dengue

(2012) Duane J. Gubler   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease-activated receptor 2 cofactors that enhance infection

(2012) M. R. Sutherland et al.   BLOOD

β-Adrenergic Receptor Stimulation Transactivates Protease-Activated Receptor 1 via Matrix Metalloproteinase 13 in Cardiac Cells

(2012) Fabrice Jaffré et al.   CIRCULATION

PAR1 contributes to influenza A virus pathogenicity in mice

(2012) Khaled Khoufache et al.   JOURNAL OF CLINICAL INVESTIGATION

Enhanced Effector Function of CD8+ T Cells From Healthy Controls and HIV-Infected Patients Occurs Through Thrombin Activation of Protease-Activated Receptor 1

(2012) Amanda Hurley et al.   JOURNAL OF INFECTIOUS DISEASES

Review: Viral infections and mechanisms of thrombosis and bleeding

(2012) M. Goeijenbier et al.   JOURNAL OF MEDICAL VIROLOGY

Coagulation Factor X Activates Innate Immunity to Human Species C Adenovirus

(2012) K. Doronin et al.   SCIENCE

Impact of Endogenous Protein C on Pulmonary Coagulation and Injury during Lethal H1N1 Influenza in Mice

(2011) Marcel Schouten et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response

(2011) Claudius Seitz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Proteinase-activated receptor-1 mediates dorsal root ganglion neuronal degeneration in HIV/AIDS

(2011) Shaona Acharjee et al.   BRAIN

Molecular mimicry between virus and host and its implications for dengue disease pathogenesis

(2011) Yee-Shin Lin et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Proteinase-activated receptor 2 activation promotes an anti-inflammatory and alternatively activated phenotype in LPS-stimulated murine macrophages

(2011) Quan M Nhu et al.   Innate Immunity

Protease-activated receptors and myocardial infarction

(2011) Silvio Antoniak et al.   IUBMB LIFE

TRIF Is a Critical Survival Factor in Viral Cardiomyopathy

(2011) A. Riad et al.   JOURNAL OF IMMUNOLOGY

Signal transduction by protease-activated receptors

(2010) Unice JK Soh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Factor V Leiden mutation does not affect coagulopathy or outcome in lethal H1N1 influenza

(2010) M. Schouten et al.   EUROPEAN RESPIRATORY JOURNAL

A critical function of toll-like receptor-3 in the induction of anti-human immunodeficiency virus activities in macrophages

(2010) Yu Zhou et al.   IMMUNOLOGY

A Role for Toll-like Receptor 3 Variants in Host Susceptibility to Enteroviral Myocarditis and Dilated Cardiomyopathy

(2010) Carlos Gorbea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effect on mortality of antipyretics in the treatment of influenza infection: systematic review and meta-analyis

(2010) Sally Eyers et al.   JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

Modifications to the Hemagglutinin Cleavage Site Control the Virulence of a Neurotropic H1N1 Influenza Virus

(2010) X. Sun et al.   JOURNAL OF VIROLOGY

Myocarditis

(2010) Lori A. Blauwet et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Tropism-Modification Strategies for Targeted Gene Delivery Using Adenoviral Vectors

(2010) Lynda Coughlan et al.   Viruses-Basel

Interferons and viral infections

(2009) Volker Fensterl et al.   BIOFACTORS

Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation

(2009) N. T. Funderburg et al.   BLOOD

Platelets and fibrinogen facilitate each other in protecting tumor cells from natural killer cytotoxicity

(2009) Sheng Zheng et al.   CANCER SCIENCE

CXCL10 Inhibits Viral Replication Through Recruitment of Natural Killer Cells in Coxsackievirus B3-Induced Myocarditis

(2009) Ji Yuan et al.   CIRCULATION RESEARCH

Salicylates and Pandemic Influenza Mortality, 1918–1919 Pharmacology, Pathology, and Historic Evidence

(2009) Karen M. Starko   CLINICAL INFECTIOUS DISEASES

Protease-activated receptor-1 regulates cytokine production and induces the suppressor of cytokine signaling-3 in microglia

(2009) Fabrizi   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Protective Role for Protease-Activated Receptor-2 against Influenza Virus Pathogenesis via an IFN- -Dependent Pathway

(2009) K. Khoufache et al.   JOURNAL OF IMMUNOLOGY

Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo

(2009) Q M Nhu et al.   Mucosal Immunology

Toll-Like Receptor 3 Signaling on Macrophages Is Required for Survival Following Coxsackievirus B4 Infection

(2009) Martin J. Richer et al.   PLoS One

A key role for Toll-like receptor-3 in disrupting the hemostasis balance on endothelial cells

(2008) A. Shibamiya et al.   BLOOD

TLRs and innate immunity

(2008) B. A. Beutler   BLOOD

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

(2008) Simon N. Waddington et al.   CELL

Mast Cells Play a Critical Role in the Pathogenesis of Viral Myocarditis

(2008) Hirokazu Higuchi et al.   CIRCULATION

Functional evolution of the TICAM-1 pathway for extrinsic RNA sensing

(2008) Tsukasa Seya et al.   IMMUNOLOGICAL REVIEWS

Analysis of Proteinase-activated Receptor 2 and TLR4 Signal Transduction

(2008) Prasad Rallabhandi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity

(2008) V. Shpacovitch et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Viral myocarditis and coagulopathy: Increased tissue factor expression and plasma thrombogenicity

(2008) Silvio Antoniak et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The contribution of PARs to inflammation and immunity to fungi

(2008) S Moretti et al.   Mucosal Immunology

Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection

(2008) Lewis H Kuller et al.   PLOS MEDICINE