Rhosin Suppressed Tumor Cell Metastasis through Inhibition of Rho/YAP Pathway and Expression of RHAMM and CXCR4 in Melanoma and Breast Cancer Cells

Exposing Hidden Targets: Combining epigenetic and immunotherapy to overcome cancer resistance

(2020) Kelly Olino et al.   SEMINARS IN CANCER BIOLOGY

Hippo-YAP1 Is a Prognosis Marker and Potentially Targetable Pathway in Advanced Gallbladder Cancer

(2020) Patricia García et al.   Cancers

The Signaling Duo CXCL12 and CXCR4: Chemokine Fuel for Breast Cancer Tumorigenesis

(2020) Karolina A. Zielińska et al.   Cancers

Combination therapy with dacarbazine and statins improved the survival rate in mice with metastatic melanoma

(2019) Masanobu Tsubaki et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Molecular Mechanisms of Breast Cancer Metastasis to the Lung: Clinical and Experimental Perspectives

(2019) Braeden Medeiros et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the modulation of YAP activity

(2019) Cinzia Zucchini et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Standard CD44 modulates YAP1 through a positive feedback loop in hepatocellular carcinoma

(2018) Zhenhai Fan et al.   BIOMEDICINE & PHARMACOTHERAPY

Tumor necrosis factor-α induces prostate cancer cell migration in lymphatic metastasis through CCR7 upregulation

(2018) Aerken Maolake et al.   CANCER SCIENCE

miR-223-RhoB signaling pathway regulates the proliferation and apoptosis of colon adenocarcinoma

(2018) Li-Juan Wei et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Artemin regulates CXCR4 expression to induce migration and invasion in pancreatic cancer cells through activation of NF-κB signaling

(2018) Juan Wang et al.   EXPERIMENTAL CELL RESEARCH

Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway

(2018) Xueran Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Collagen abundance controls melanoma phenotypes through lineage-specific microenvironment sensing

(2018) Zsofia Miskolczi et al.   ONCOGENE

Paving the Rho in cancer metastasis: Rho GTPases and beyond

(2018) Sepp Jansen et al.   PHARMACOLOGY & THERAPEUTICS

YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD

(2018) Mengxue Yu et al.   Cell Death & Disease

YAP regulates periodontal ligament cell differentiation into myofibroblast interacted with RhoA/ROCK pathway

(2018) Yao He et al.   JOURNAL OF CELLULAR PHYSIOLOGY

RhoA and RhoC are involved in stromal cell-derived factor-1-induced cell migration by regulating F-actin redistribution and assembly

(2017) Jixian Luo et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nivolumab and pembrolizumab: Monoclonal antibodies against programmed cell death-1 (PD-1) that are interchangeable

(2017) Vinay Prasad et al.   SEMINARS IN ONCOLOGY

Management of intracranial melanomas in the era of precision medicine

(2017) Grace J. Young et al.   Oncotarget

The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer

(2017) Valentina Mele et al.   Oncotarget

Overcoming resistance to targeted therapy with immunotherapy and combination therapy for metastatic melanoma

(2017) Hilary R. Keller et al.   Oncotarget

MRTF potentiates TEAD‐YAP transcriptional activity causing metastasis

(2016) Tackhoon Kim et al.   EMBO JOURNAL

Annexin-A1 controls an ERK-RhoA–NFκB activation loop in breast cancer cells

(2015) Pradeep Bist et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer

(2015) J. Xiang et al.   MOLECULAR CANCER THERAPEUTICS

HOXD10 acts as a tumor-suppressive factor via inhibition of the RHOC/AKT/MAPK pathway in human cholangiocellular carcinoma

(2015) HAIXIA YANG et al.   ONCOLOGY REPORTS

Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression

(2015) Shiyi Yu et al.   Oncotarget

RhoE is required for contact inhibition and negatively regulates tumor initiation and progression

(2015) Marta Hernández-Sánchez et al.   Oncotarget

Role of receptor for hyaluronan-mediated motility (RHAMM) in human head and neck cancers

(2014) Hideo Shigeishi et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

CC chemokine receptor-like 1 functions as a tumour suppressor by impairing CCR7-related chemotaxis in hepatocellular carcinoma

(2014) Jie-Yi Shi et al.   JOURNAL OF PATHOLOGY

Critical functions of RhoB in support of glioblastoma tumorigenesis

(2014) Yufang Ma et al.   NEURO-ONCOLOGY

Marine algal fucoxanthin inhibits the metastatic potential of cancer cells

(2013) Tae-Wook Chung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpression of YAP and TAZ Is an Independent Predictor of Prognosis in Colorectal Cancer and Related to the Proliferation and Metastasis of Colon Cancer Cells

(2013) Lijuan Wang et al.   PLoS One

SurvExpress: An Online Biomarker Validation Tool and Database for Cancer Gene Expression Data Using Survival Analysis

(2013) Raul Aguirre-Gamboa et al.   PLoS One

RhoE Promotes Metastasis in Gastric Cancer through a Mechanism Dependent on Enhanced Expression of CXCR4

(2013) Bin Feng et al.   PLoS One

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

(2013) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational Design of Small Molecule Inhibitors Targeting RhoA Subfamily Rho GTPases

(2012) Xun Shang et al.   CHEMISTRY & BIOLOGY

The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain

(2012) J. M. Lamar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Receptor for Hyaluronic Acid-mediated Motility (RHAMM) in Low Molecular Weight Hyaluronan (LMWHA)-mediated Fibrosarcoma Cell Adhesion

(2011) Katerina Kouvidi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Gene Expression Profiling-Based Identification of Molecular Subtypes in Stage IV Melanomas with Different Clinical Outcome

(2010) G. Jonsson et al.   CLINICAL CANCER RESEARCH

Hyaluronan-CD44 Interaction Promotes c-Src-mediated Twist Signaling, MicroRNA-10b Expression, and RhoA/RhoC Up-regulation, Leading to Rho-kinase-associated Cytoskeleton Activation and Breast Tumor Cell Invasion

(2010) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway

(2010) Yasuhiro Kidera et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Rnd3 Regulation of the Actin Cytoskeleton Promotes Melanoma Migration and Invasive Outgrowth in Three Dimensions

(2009) R. M. Klein et al.   CANCER RESEARCH

Expression of RhoA and RhoC in colorectal carcinoma and its relations with clinicopathological parameters

(2009) Hai-bo Wang et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

The role of RhoC in growth and metastatic capacity of melanoma

(2009) Barbara Boone et al.   JOURNAL OF CUTANEOUS PATHOLOGY

PRL-3 facilitates angiogenesis and metastasis by increasing ERK phosphorylation and up-regulating the levels and activities of Rho-A/C in lung cancer

(2009) Jian Ming et al.   PATHOLOGY

Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen

(2008) Sherene Loi et al.   BMC GENOMICS

The Humoral Immune System Has a Key Prognostic Impact in Node-Negative Breast Cancer

(2008) M. Schmidt et al.   CANCER RESEARCH