Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway

GOLM1 Modulates EGFR/RTK Cell-Surface Recycling to Drive Hepatocellular Carcinoma Metastasis

(2016) Qing-Hai Ye et al.   CANCER CELL

Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis

(2016) L.-Y. Ye et al.   CANCER RESEARCH

Role of epithelial to mesenchymal transition in hepatocellular carcinoma

(2016) Gianluigi Giannelli et al.   JOURNAL OF HEPATOLOGY

Progress in systemic therapy of advanced hepatocellular carcinoma

(2016) Xin-Lei Gong et al.   WORLD JOURNAL OF GASTROENTEROLOGY

A MAPK-Driven Feedback Loop Suppresses Rac Activity to Promote RhoA-Driven Cancer Cell Invasion

(2016) Joseph H. R. Hetmanski et al.   PLoS Computational Biology

Compromised MAPK signaling in human diseases: an update

(2015) Eun Kyung Kim et al.   ARCHIVES OF TOXICOLOGY

Supervillin binds the Rac/Rho-GEF Trio and increases Trio-mediated Rac1 activation

(2015) Kyonghee Son et al.   Cytoskeleton

Management of Hepatocellular Carcinoma: Current Status and Future Directions

(2015) Jennifer S Au et al.   Gut and Liver

Temporal trends in population-based death rates associated with chronic liver disease and liver cancer in the United States over the last 30 years

(2014) Yuhree Kim et al.   CANCER

Low Intensity Pulsed Ultrasound (LIPUS) Influences the Multilineage Differentiation of Mesenchymal Stem and Progenitor Cell Lines through ROCK-Cot/Tpl2-MEK-ERK Signaling Pathway

(2014) Joji Kusuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways

(2014) P Wang et al.   ONCOGENE

Hepatocellular carcinoma review: Current treatment, and evidence-based medicine

(2014) Ali Raza   WORLD JOURNAL OF GASTROENTEROLOGY

G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade

(2013) James D. Robinson et al.   CELLULAR SIGNALLING

Epithelial-mesenchymal plasticity in carcinoma metastasis

(2013) J. H. Tsai et al.   GENES & DEVELOPMENT

Supervillin-mediated Suppression of p53 Protein Enhances Cell Survival

(2013) Zhiyou Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Supervillin binding to myosin II and synergism with anillin are required for cytokinesis

(2013) Tara C. Smith et al.   MOLECULAR BIOLOGY OF THE CELL

Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells

(2013) D. M. Gilkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesothelin Binding to CA125/MUC16 Promotes Pancreatic Cancer Cell Motility and Invasion via MMP-7 Activation

(2013) Shih-Hsun Chen et al.   Scientific Reports

Supervillin couples myosin-dependent contractility to podosomes and enables their turnover

(2012) R. Bhuwania et al.   JOURNAL OF CELL SCIENCE

Hypoxia-reoxygenation-induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase

(2012) Muhammad Aslam et al.   JOURNAL OF PHYSIOLOGY-LONDON

Involvement of HIF-1α in MLCK-dependent Endothelial Barrier Dysfunction in Hypoxia

(2011) Huabing Qi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Prolyl Hydroxylase Domain (PHD) 2 Affects Cell Migration and F-actin Formation via RhoA/Rho-associated Kinase-dependent Cofilin Phosphorylation

(2010) Sabine Vogel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Membrane-Associated Protein, Supervillin, Accelerates F-Actin-Dependent Rapid Integrin Recycling and Cell Motility

(2010) Zhiyou Fang et al.   TRAFFIC

EMT, the cytoskeleton, and cancer cell invasion

(2009) Mahmut Yilmaz et al.   CANCER AND METASTASIS REVIEWS

Smooth Muscle Archvillin Is an ERK Scaffolding Protein

(2009) Samudra S. Gangopadhyay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Current Management of Hepatocellular Carcinoma

(2009) Manuel Mendizabal et al.   MEDICAL CLINICS OF NORTH AMERICA

Supervillin Reorganizes the Actin Cytoskeleton and Increases Invadopodial Efficiency

(2008) Jessica L. Crowley et al.   MOLECULAR BIOLOGY OF THE CELL

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY