Renaissance of VDAC: New Insights on a Protein Family at the Interface between Mitochondria and Cytosol

A High Resolution Mass Spectrometry Study Reveals the Potential of Disulfide Formation in Human Mitochondrial Voltage-Dependent Anion Selective Channel Isoforms (hVDACs)

(2020) Maria G. G. Pittalà et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A lower affinity to cytosolic proteins reveals VDAC3 isoform-specific role in mitochondrial biology

(2020) María Queralt-Martín et al.   JOURNAL OF GENERAL PHYSIOLOGY

Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing

(2020) Chirag Nepal et al.   Nature Communications

Cysteine Oxidations in Mitochondrial Membrane Proteins: The Case of VDAC Isoforms in Mammals

(2020) Simona Reina et al.   Frontiers in Cell and Developmental Biology

Is the Secret of VDAC Isoforms in Their Gene Regulation? Characterization of Human VDAC Genes Expression Profile, Promoter Activity, and Transcriptional Regulators

(2020) Federica Zinghirino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NRF-1 and HIF-1α contribute to modulation of human VDAC1 gene promoter during starvation and hypoxia in HeLa cells

(2020) Francesca Guarino et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Post-Translational Modification Analysis of VDAC1 in ALS-SOD1 Model Cells Reveals Specific Asparagine and Glutamine Deamidation

(2020) Maria Gaetana Giovanna Pittalà et al.   Antioxidants

Dual Role of Mitochondrial Porin in Metabolite Transport across the Outer Membrane and Protein Transfer to the Inner Membrane

(2019) Lars Ellenrieder et al.   MOLECULAR CELL

Deletion of Voltage-Dependent Anion Channel 1 knocks mitochondria down triggering metabolic rewiring in yeast

(2019) Andrea Magrì et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Expression Atlas update: from tissues to single cells

(2019) Irene Papatheodorou et al.   NUCLEIC ACIDS RESEARCH

Post-translational modifications of VDAC1 and VDAC2 cysteines from rat liver mitochondria

(2018) Rosaria Saletti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

yVDAC2, the second mitochondrial porin isoform of Saccharomyces cerevisiae

(2018) Carlo Guardiani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Anti-Cancer Compounds Targeted to VDAC: Potential and Perspectives

(2018) Simona Reina et al.   CURRENT MEDICINAL CHEMISTRY

Myc-Associated Zinc Finger Protein Regulates the Pro-Inflammatory Response in Colitis and Colon Cancer via STAT3 Signaling

(2018) Daniel Triner et al.   MOLECULAR AND CELLULAR BIOLOGY

Dynamic control of neural stem cells by bHLH factors

(2018) Ryoichiro Kageyama et al.   NEUROSCIENCE RESEARCH

Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells

(2018) Enming Zhang et al.   Cell Metabolism

VDAC2 enables BAX to mediate apoptosis and limit tumor development

(2018) Hui San Chin et al.   Nature Communications

Recombinant yeast VDAC2:a comparison of electrophysiological features with the native form

(2018) Andrea Magrì et al.   FEBS Open Bio

Identification of new channels by systematic analysis of the mitochondrial outer membrane

(2017) Vivien Krüger et al.   JOURNAL OF CELL BIOLOGY

VDAC1 is a molecular target in glioblastoma, with its depletion leading to reprogrammed metabolism and reversed oncogenic properties

(2017) Tasleem Arif et al.   NEURO-ONCOLOGY

Association of the VDAC3 gene polymorphism with sperm count in Han-Chinese population with idiopathic male infertility

(2017) Lianjun Pan et al.   Oncotarget

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

(2017) Marcel Morgenstern et al.   Cell Reports

Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target

(2017) Amadou K. S. Camara et al.   Frontiers in Physiology

FANTOM5 CAGE profiles of human and mouse samples

(2017) Shuhei Noguchi et al.   Scientific Data

Recombinant Human Voltage Dependent Anion Selective Channel Isoform 3 (hVDAC3) Forms Pores with a Very Small Conductance

(2017) Vanessa Checchetto et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Role of cysteines in mammalian VDAC isoforms' function

(2016) Vito De Pinto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

VDAC2-specific cellular functions and the underlying structure

(2016) Shamim Naghdi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction

(2016) Danya Ben-Hail et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VDAC3 as a sensor of oxidative state of the intermembrane space of mitochondria: the putative role of cysteine residue modifications

(2016) Simona Reina et al.   Oncotarget

VDAC3 gating is activated by suppression of disulfide-bond formation between the N-terminal region and the bottom of the pore

(2015) Masateru Okazaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Hes1: a key role in stemness, metastasis and multidrug resistance

(2015) Zi-Hao Liu et al.   CANCER BIOLOGY & THERAPY

α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease

(2015) Tatiana K. Rostovtseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

High Resolution Structure and Double Electron-Electron Resonance of the Zebrafish Voltage-dependent Anion Channel 2 Reveal an Oligomeric Population

(2014) Johann Schredelseker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Family of Proteins: Transcriptional Modifiers with Multi-Functional Protein Interfaces

(2013) M. Labrecque et al.   CURRENT MOLECULAR MEDICINE

The Voltage-Dependent Anion Selective Channel 1 (VDAC1) Topography in the Mitochondrial Outer Membrane as Detected in Intact Cell

(2013) Marianna F. Tomasello et al.   PLoS One

Is the mitochondrial outermembrane protein VDAC1 therapeutic target for Alzheimer's disease?

(2012) P. Hemachandra Reddy   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

(2011) Julius Anckar et al.   Annual Review of Biochemistry

VDAC proteomics: Post-translation modifications

(2011) Janos Kerner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Role of ZBP-89 in human globin gene regulation and erythroid differentiation

(2011) A. J. Woo et al.   BLOOD

Characterization of human VDAC isoforms: A peculiar function for VDAC3?

(2010) Vito De Pinto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

ZBTB7 Overexpression Contributes to Malignancy in Breast Cancer

(2010) Hongyan Qu et al.   CANCER INVESTIGATION

Mitochondrial metabolite transport

(2010) Ferdinando Palmieri et al.   Essays in Biochemistry

Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis

(2010) N. Keinan et al.   MOLECULAR AND CELLULAR BIOLOGY

Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS

(2010) Adrian Israelson et al.   NEURON

The Transcription Factor Cux1 Regulates Dendritic Morphology of Cortical Pyramidal Neurons

(2010) Ning Li et al.   PLoS One

Retinoic acid in development: towards an integrated view

(2008) Karen Niederreither et al.   NATURE REVIEWS GENETICS

Structure of the human voltage-dependent anion channel

(2008) M. Bayrhuber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating

(2008) R. Ujwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles

(2008) S. Hiller et al.   SCIENCE