Disentangling Biomolecular Corona Interactions With Cell Receptors and Implications for Targeting of Nanomedicines

Tuning liposome composition to modulate the corona forming in human serum and uptake by cells

(2020) Keni Yang et al.   Acta Biomaterialia

The entry of nanoparticles into solid tumours

(2020) Shrey Sindhwani et al.   NATURE MATERIALS

Polymeric Nanoparticles with Neglectable Protein Corona

(2020) Irina Alberg et al.   Small

Unbiased Identification of the Liposome Protein Corona using Photoaffinity-based Chemoproteomics

(2020) Roy Pattipeiluhu et al.   ACS Central Science

The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy

(2020) Valentina Francia et al.   BIOCONJUGATE CHEMISTRY

Identification of Cell-Surface Proteins Endocytosed by Human Brain Microvascular Endothelial Cells In Vitro

(2020) Shingo Ito et al.   Pharmaceutics

Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association

(2020) Hossein Mohammad-Beigi et al.   Nature Communications

Graphene Nanoflake Uptake Mediated by Scavenger Receptors

(2019) Fatima Alnasser et al.   NANO LETTERS

Targeting strategies for improving the efficacy of nanomedicine in oncology

(2019) Gonzalo Villaverde et al.   Beilstein Journal of Nanotechnology

Transcytosis to Cross the Blood Brain Barrier, New Advancements and Challenges

(2019) Victor M. Pulgar   Frontiers in Neuroscience

Protein Corona Fingerprints of Liposomes: New Opportunities for Targeted Drug Delivery and Early Detection in Pancreatic Cancer

(2019) Sara Palchetti et al.   Pharmaceutics

Clinical cancer nanomedicine

(2019) Joy Wolfram et al.   Nano Today

Mapping Molecular Structure of Protein Locating on Nanoparticles with Limited Proteolysis

(2019) Yaokai Duan et al.   ANALYTICAL CHEMISTRY

Corona Composition Can Affect the Mechanisms Cells Use to Internalize Nanoparticles

(2019) Valentina Francia et al.   ACS Nano

Intrapulmonary Cellular-Level Distribution of Inhaled Nanoparticles with Defined Functional Groups and Its Correlations with Protein Corona and Inflammatory Response

(2019) Bohan Yin et al.   ACS Nano

Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis

(2019) Alejandro Gómez Toledo et al.   Nature Communications

The interaction between nanoparticles-protein corona complex and cells and its toxic effect on cells

(2019) Na Liu et al.   CHEMOSPHERE

Differential Recognition of Nanoparticle Protein Corona and Modified Low-Density Lipoprotein by Macrophage Receptor with Collagenous Structure

(2018) Sandra Lara et al.   ACS Nano

Preservation of the soft protein corona in distinct flow allows identification of weakly bound proteins

(2018) C. Weber et al.   Acta Biomaterialia

Cell-surface proteomics for the identification of novel therapeutic targets in cancer

(2018) Laura Kuhlmann et al.   Expert Review of Proteomics

Label-free in-flow detection of receptor recognition motifs on the biomolecular corona of nanoparticles

(2018) M. Gianneli et al.   Nanoscale

Biological recognition of graphene nanoflakes

(2018) V. Castagnola et al.   Nature Communications

Involvement of Insulin-Degrading Enzyme in Insulin- and Atrial Natriuretic Peptide-Sensitive Internalization of Amyloid-β Peptide in Mouse Brain Capillary Endothelial Cells

(2018) Shingo Ito et al.   JOURNAL OF ALZHEIMERS DISEASE

Minimum information reporting in bio–nano experimental literature

(2018) Matthew Faria et al.   Nature Nanotechnology

Intracellular transport and regulation of transcytosis across the blood–brain barrier

(2018) Roberto Villaseñor et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The influence of surface charge on serum protein interaction and cellular uptake: studies with dendritic polyglycerols and dendritic polyglycerol-coated gold nanoparticles

(2017) Tony Bewersdorff et al.   International Journal of Nanomedicine

Spatial Mapping of Protein Adsorption on Mesoporous Silica Nanoparticles by Stochastic Optical Reconstruction Microscopy

(2017) Alden M. Clemments et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Experimental separation steps influence the protein content of corona around mesoporous silica nanoparticles

(2017) C. Pisani et al.   Nanoscale

The evolving landscape of drug products containing nanomaterials in the United States

(2017) Sheetal R. D'Mello et al.   Nature Nanotechnology

Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis

(2017) Benjamin J. Andreone et al.   NEURON

Super-Resolution Microscopy Unveils Dynamic Heterogeneities in Nanoparticle Protein Corona

(2017) Natalia Feiner-Gracia et al.   Small

Biological Identity of Nanoparticles In Vivo : Clinical Implications of the Protein Corona

(2017) Giulio Caracciolo et al.   TRENDS IN BIOTECHNOLOGY

Determining Cell-surface Expression and Endocytic Rate of Proteins in Primary Astrocyte Cultures Using Biotinylation

(2017) Daniel Kai Long Tham et al.   Jove-Journal of Visualized Experiments

Understanding the Kinetics of Protein–Nanoparticle Corona Formation

(2016) Oriol Vilanova et al.   ACS Nano

Exploring Cellular Interactions of Liposomes Using Protein Corona Fingerprints and Physicochemical Properties

(2016) Arafeh Bigdeli et al.   ACS Nano

Controlling the Stealth Effect of Nanocarriers through Understanding the Protein Corona

(2016) Susanne Schöttler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?

(2016) F. Danhier   JOURNAL OF CONTROLLED RELEASE

Mapping of Molecular Structure of the Nanoscale Surface in Bionanoparticles

(2016) Luciana M. Herda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction

(2016) Nazanin Hoshyar et al.   Nanomedicine

Nanoparticles-cell association predicted by protein corona fingerprints

(2016) S. Palchetti et al.   Nanoscale

Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers

(2016) Susanne Schöttler et al.   Nature Nanotechnology

Current understanding of interactions between nanoparticles and the immune system

(2016) Marina A. Dobrovolskaia et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In situ characterization of nanoparticle biomolecular interactions in complex biological media by flow cytometry

(2016) Maria Cristina Lo Giudice et al.   Nature Communications

Does Nanomedicine Have a Delivery Problem?

(2016) Michael Torrice   ACS Central Science

Cancer nanomedicine: is targeting our target?

(2016) Twan Lammers et al.   Nature Reviews Materials

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Elasticity of Nanoparticles Influences Their Blood Circulation, Phagocytosis, Endocytosis, and Targeting

(2015) Aaron C. Anselmo et al.   ACS Nano

In Vivo Biomolecule Corona around Blood-Circulating, Clinically Used and Antibody-Targeted Lipid Bilayer Nanoscale Vesicles

(2015) Marilena Hadjidemetriou et al.   ACS Nano

Towards understanding of nanoparticle–protein corona

(2015) Cuicui Ge et al.   ARCHIVES OF TOXICOLOGY

Protein Corona of Nanoparticles: Distinct Proteins Regulate the Cellular Uptake

(2015) Sandra Ritz et al.   BIOMACROMOLECULES

Prediction of nanoparticles-cell association based on corona proteins and physicochemical properties

(2015) Rong Liu et al.   Nanoscale

Characterization of the bionano interface and mapping extrinsic interactions of the corona of nanomaterials

(2015) D. J. O'Connell et al.   Nanoscale

Mapping protein binding sites on the biomolecular corona of nanoparticles

(2015) Philip M. Kelly et al.   Nature Nanotechnology

A holistic approach to targeting disease with polymeric nanoparticles

(2015) Christopher J. Cheng et al.   NATURE REVIEWS DRUG DISCOVERY

Scavenger Receptor Structure and Function in Health and Disease

(2015) Izma Zani et al.   Cells

Investigating the Impact of Nanoparticle Size on Active and Passive Tumor Targeting Efficiency

(2014) Edward A. Sykes et al.   ACS Nano

Fabrication of Corona-Free Nanoparticles with Tunable Hydrophobicity

(2014) Daniel F. Moyano et al.   ACS Nano

Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles

(2014) Carl D. Walkey et al.   ACS Nano

Secondary Structure of Corona Proteins Determines the Cell Surface Receptors Used by Nanoparticles

(2014) Candace C. Fleischer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Spatial Mapping and Quantification of Soft and Hard Protein Coronas at Silver Nanocubes

(2014) Teodora Miclăuş et al.   NANO LETTERS

Suppression of nanoparticle cytotoxicity approaching in vivo serum concentrations: limitations of in vitro testing for nanosafety

(2014) Jong Ah Kim et al.   Nanoscale

Time to deliver

(2014)   NATURE BIOTECHNOLOGY

Quantitative profiling of the protein coronas that form around nanoparticles

(2014) Dominic Docter et al.   Nature Protocols

Zwitterionic-Coated “Stealth” Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System

(2014) Karina Pombo García et al.   Small

Clathrin-independent pathways do not contribute significantly to endocytic flux

(2014) Vassilis Bitsikas et al.   eLife

Brain Slice Biotinylation: An Ex Vivo Approach to Measure Region-specific Plasma Membrane Protein Trafficking in Adult Neurons

(2014) Luke R. Gabriel et al.   Jove-Journal of Visualized Experiments

Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood–Brain Barrier

(2014) Julia Georgieva et al.   Pharmaceutics

Selective Targeting Capability Acquired with a Protein Corona Adsorbed on the Surface of 1,2-Dioleoyl-3-trimethylammonium Propane/DNA Nanoparticles

(2013) Giulio Caracciolo et al.   ACS Applied Materials & Interfaces

Mechanism of Polyplex- and Lipoplex-Mediated Delivery of Nucleic Acids: Real-Time Visualization of Transient Membrane Destabilization without Endosomal Lysis

(2013) Zia ur Rehman et al.   ACS Nano

Surface proteomic analysis of osteosarcoma identifies EPHA2 as receptor for targeted drug delivery

(2013) J PosthumaDeBoer et al.   BRITISH JOURNAL OF CANCER

Shaping cancer nanomedicine: the effect of particle shape on the in vivo journey of nanoparticles

(2013) Randall Toy et al.   Nanomedicine

Effect of polyethyleneglycol (PEG) chain length on the bio–nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells

(2013) Daniela Pozzi et al.   Nanoscale

Strategies for advancing cancer nanomedicine

(2013) Vikash P. Chauhan et al.   NATURE MATERIALS

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

The Cell-based L-Glutathione Protection Assays to Study Endocytosis and Recycling of Plasma Membrane Proteins

(2013) Kristine M. Cihil et al.   Jove-Journal of Visualized Experiments

Cancer nanomedicines: So many papers and so few drugs!

(2012) Vincent J. Venditto et al.   ADVANCED DRUG DELIVERY REVIEWS

Surface Charge Switchable Nanoparticles Based on Zwitterionic Polymer for Enhanced Drug Delivery to Tumor

(2012) You-Yong Yuan et al.   ADVANCED MATERIALS

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Designing the nanoparticle–biomolecule interface for “targeting and therapeutic delivery”

(2012) Eugene Mahon et al.   JOURNAL OF CONTROLLED RELEASE

Endocytosis and Intracellular Trafficking as Gateways for Nanomedicine Delivery: Opportunities and Challenges

(2012) Ruth Duncan et al.   MOLECULAR PHARMACEUTICS

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Nanoparticle Size Is a Critical Physicochemical Determinant of the Human Blood Plasma Corona: A Comprehensive Quantitative Proteomic Analysis

(2011) Stefan Tenzer et al.   ACS Nano

Protein−Nanoparticle Interactions: Opportunities and Challenges

(2011) Morteza Mahmoudi et al.   CHEMICAL REVIEWS

Protein kinase A inhibition modulates the intracellular routing of gene delivery vehicles in HeLa cells, leading to productive transfection

(2011) Zia ur Rehman et al.   JOURNAL OF CONTROLLED RELEASE

Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies

(2011) Tore-Geir Iversen et al.   Nano Today

Recent insights into factors affecting remnant lipoprotein uptake

(2010) Kevin Jon Williams et al.   CURRENT OPINION IN LIPIDOLOGY

Isolation of cell surface proteins for mass spectrometry-based proteomics

(2010) Sarah Elschenbroich et al.   Expert Review of Proteomics

To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

(2010) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Endocytosis of nanomedicines

(2010) Gaurav Sahay et al.   JOURNAL OF CONTROLLED RELEASE

Endosomal escape pathways for delivery of biologicals

(2010) Amir K. Varkouhi et al.   JOURNAL OF CONTROLLED RELEASE

Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

(2010) Akin Akinc et al.   MOLECULAR THERAPY

Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood–Brain Barrier Endothelial Cells In Vitro

(2010) Julia V Georgieva et al.   MOLECULAR THERAPY

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

(2010) Zhou J. Deng et al.   Nature Nanotechnology

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Size and shape effects in the biodistribution of intravascularly injected particles

(2009) P. Decuzzi et al.   JOURNAL OF CONTROLLED RELEASE

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biotinylation reagents for the study of cell surface proteins

(2008) Giuliano Elia   PROTEOMICS