Metabolic Plasticity Is an Essential Requirement of Acquired Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia

Mitochondrial Determinants of Doxorubicin-Induced Cardiomyopathy

(2020) Kendall B. Wallace et al.   CIRCULATION RESEARCH

Imatinib and Dasatinib Provoke Mitochondrial Dysfunction Leading to Oxidative Stress in C2C12 Myotubes and Human RD Cells

(2020) Jamal Bouitbir et al.   Frontiers in Pharmacology

Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0)

(2019) Huaiyu Mi et al.   Nature Protocols

Multiomic Profiling of Tyrosine Kinase Inhibitor-Resistant K562 Cells Suggests Metabolic Reprogramming To Promote Cell Survival

(2019) Brett M. Noel et al.   JOURNAL OF PROTEOME RESEARCH

Real-Time NMR Spectroscopy for Studying Metabolism

(2019) Islam Alshamleh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Proline Cycle As a Potential Cancer Therapy Target

(2018) John J. Tanner et al.   BIOCHEMISTRY

Targeting Glutamine Metabolism for Cancer Treatment

(2018) Yeon-Kyung Choi et al.   Biomolecules & Therapeutics

The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer

(2018) Michaela Poliaková et al.   Molecular Cancer

The second generation tyrosine kinase inhibitor dasatinib induced eryptosis in human erythrocytes—An in vitro study

(2018) Wai Yin Chan et al.   TOXICOLOGY LETTERS

Influence of the Tumor Microenvironment on Cancer Cells Metabolic Reprogramming

(2018) Victoire Gouirand et al.   Frontiers in Oncology

Transporter and Lysosomal Mediated (Multi)drug Resistance to Tyrosine Kinase Inhibitors and Potential Strategies to Overcome Resistance

(2018) Daniel de Klerk et al.   Cancers

The Influence of Metabolism on Drug Response in Cancer

(2018) Esther A. Zaal et al.   Frontiers in Oncology

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

(2017) Matthew J. Hangauer et al.   NATURE

Sugar fuels T-cell memory

(2017) Joanna Olivas et al.   NATURE CELL BIOLOGY

Pathview Web: user friendly pathway visualization and data integration

(2017) Weijun Luo et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial composition and function under the control of hypoxia

(2017) Dominik C. Fuhrmann et al.   Redox Biology

GSTM1 and GSTP1 , but not GSTT1 genetic polymorphisms are associated with chronic myeloid leukemia risk and treatment response

(2016) Natalia Weich et al.   Cancer Epidemiology

Glycogen metabolism has a key role in the cancer microenvironment and provides new targets for cancer therapy

(2016) Christos E. Zois et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program

(2016) Esther Aguilar et al.   STEM CELLS

Tracer-Based Metabolic NMR-Based Flux Analysis in a Leukaemia Cell Line

(2016) John B. Carrigan et al.   ChemPlusChem

Proline metabolism and cancer

(2015) James M. Phang et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Ageing is a risk factor in imatinib mesylate cardiotoxicity

(2014) Wael Maharsy et al.   EUROPEAN JOURNAL OF HEART FAILURE

The pentose phosphate pathway and cancer

(2014) Krushna C. Patra et al.   TRENDS IN BIOCHEMICAL SCIENCES

Characterization of the Usage of the Serine Metabolic Network in Human Cancer

(2014) Mahya Mehrmohamadi et al.   Cell Reports

The function and the role of the mitochondrial glycerol-3-phosphate dehydrogenase in mammalian tissues

(2012) Tomáš Mráček et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Glucose Utilization via Glycogen Phosphorylase Sustains Proliferation and Prevents Premature Senescence in Cancer Cells

(2012) Elena Favaro et al.   Cell Metabolism

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Energy metabolism of cancer: Glycolysis versus oxidative phosphorylation (Review)

(2012) JIE ZHENG   Oncology Letters

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Exploiting Mitochondrial Dysfunction for Effective Elimination of Imatinib-Resistant Leukemic Cells

(2011) Jérome Kluza et al.   PLoS One

Carbon metabolism and the sign of control coefficients in metabolic adaptations underlying K-ras transformation

(2010) Pedro de Atauri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming

(2010) F Zhao et al.   ONCOGENE

Mitochondrial and plasma membrane lactate transporter and lactate dehydrogenase isoform expression in breast cancer cell lines

(2010) Rajaa Hussien et al.   PHYSIOLOGICAL GENOMICS

Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets

(2009) P. Vizan et al.   CARCINOGENESIS

The metabolic consequences of imatinib mesylate: Changes on glucose, lypidic and bone metabolism

(2009) Massimo Breccia et al.   LEUKEMIA RESEARCH

Nilotinib: A second-generation tyrosine kinase inhibitor for chronic myeloid leukemia

(2009) Massimo Breccia et al.   LEUKEMIA RESEARCH

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY