Imatinib and Dasatinib Provoke Mitochondrial Dysfunction Leading to Oxidative Stress in C2C12 Myotubes and Human RD Cells

Mitochondrial Superoxide Dismutase: What the Established, the Intriguing, and the Novel Reveal About a Key Cellular Redox Switch

(2020) Flavio R. Palma et al.   ANTIOXIDANTS & REDOX SIGNALING

Skeletal muscle toxicity associated with tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia

(2019) L. Janssen et al.   LEUKEMIA

Insulin prevents and reverts simvastatin-induced toxicity in C2C12 skeletal muscle cells

(2019) Gerda M. Sanvee et al.   Scientific Reports

Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study

(2019) Gilles R Dagenais et al.   LANCET

The true value of second-generation TKIs as first-line therapy in chronic myeloid leukaemia

(2019) Claire N Andrews et al.   Lancet Haematology

Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib

(2019) Jamal Bouitbir et al.   TOXICOLOGY

Properties of FDA-approved small molecule protein kinase inhibitors: A 2020 update

(2019) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Multitargeted kinase inhibitors imatinib, sorafenib and sunitinib perturb energy metabolism and cause cytotoxicity to cultured C2C12 skeletal muscle derived myotubes

(2018) Vijaya L. Damaraju et al.   BIOCHEMICAL PHARMACOLOGY

Toxic myopathies

(2018) Mamatha Pasnoor et al.   CURRENT OPINION IN NEUROLOGY

PGC-1β modulates statin-associated myotoxicity in mice

(2018) François Singh et al.   ARCHIVES OF TOXICOLOGY

Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines

(2017) Cécile Mingard et al.   JOURNAL OF APPLIED TOXICOLOGY

Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents

(2017) Patrizia Haegler et al.   TOXICOLOGICAL SCIENCES

Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis

(2017) Franziska Paech et al.   Frontiers in Pharmacology

Statins Trigger Mitochondrial Reactive Oxygen Species-Induced Apoptosis in Glycolytic Skeletal Muscle

(2016) Jamal Bouitbir et al.   ANTIOXIDANTS & REDOX SIGNALING

Calcium and reactive oxygen species in regulation of the mitochondrial permeability transition and of programmed cell death in yeast

(2016) Michela Carraro et al.   CELL CALCIUM

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

(2016) Martin D. Brand   FREE RADICAL BIOLOGY AND MEDICINE

Long-Term Side Effects of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia

(2016) Lauren Caldemeyer et al.   Current Hematologic Malignancy Reports

Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition

(2015) Tom J.J. Schirris et al.   Cell Metabolism

Patient-reported adverse drug reactions and their influence on adherence and quality of life of chronic myeloid leukemia patients on per oral tyrosine kinase inhibitor treatment

(2015) Meri Kekale et al.   Patient Preference and Adherence

Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling

(2013) Eva-Maria Hanschmann et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria as a Target of Environmental Toxicants

(2013) Joel N. Meyer et al.   TOXICOLOGICAL SCIENCES

Oxidative stress and disuse muscle atrophy

(2012) Scott K. Powers et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Tyrosine-kinase inhibitors and patient-reported outcomes in chronic myeloid leukemia: A systematic review

(2012) Fabio Efficace et al.   LEUKEMIA RESEARCH

Serum creatine kinase increase in patients treated with tyrosine kinase inhibitors for solid tumors

(2012) Antoine Adenis et al.   MEDICAL ONCOLOGY

Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases

(2011) Tohru Fukai et al.   ANTIOXIDANTS & REDOX SIGNALING

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Metabolism considerations for kinase inhibitors in cancer treatment

(2010) Derek R Duckett et al.   Expert Opinion on Drug Metabolism & Toxicology

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting

(2009) J. M. McClung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Safranine O as a fluorescent probe for mitochondrial membrane potential studied on the single particle level and in suspension

(2009) I. V. Perevoshchikova et al.   BIOCHEMISTRY-MOSCOW

Effect of the Multitargeted Tyrosine Kinase Inhibitors Imatinib, Dasatinib, Sunitinib, and Sorafenib on Mitochondrial Function in Isolated Rat Heart Mitochondria and H9c2 Cells

(2008) Yvonne Will et al.   TOXICOLOGICAL SCIENCES