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Title
BRAF inhibition protects against hearing loss in mice
Authors
Keywords
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Journal
Science Advances
Volume 6, Issue 49, Pages eabd0561
Publisher
American Association for the Advancement of Science (AAAS)
Online
2020-12-03
DOI
10.1126/sciadv.abd0561
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- (2020) Katharine Fernandez et al. HEARING RESEARCH
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- (2019) Xiaoyu Yu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Allicin Protects against Cisplatin-Induced Stria Vascularis Damage: Possible Relation to Inhibition of Caspase-3 and PARP-1-AIF-Mediated Apoptotic Pathways
- (2019) Jing Cai et al. ORL-Journal for Oto-Rhino-Laryngology Head and Neck Surgery
- Local Drug Delivery for Prevention of Hearing Loss
- (2019) Leonard P. Rybak et al. Frontiers in Cellular Neuroscience
- Practical approaches to evaluating and optimizing brain exposure in early drug discovery
- (2019) Burgess B. Freeman et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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- (2019) Rajesh Kumar et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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- (2019) Richard A. Ward et al. JOURNAL OF MEDICINAL CHEMISTRY
- Hearing loss before and after cisplatin-based chemotherapy in testicular cancer survivors: a longitudinal study
- (2018) Hege S. Haugnes et al. ACTA ONCOLOGICA
- Recent developments and obstacles in the treatment of melanoma with BRAF and MEK inhibitors
- (2018) Mohd Wahid et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Long-Term Outcomes in Patients With BRAF V600–Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib
- (2018) Georgina V. Long et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2018) Penelope R. Brock et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2018) Lauretta Odogwu et al. ONCOLOGIST
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- (2018) Anni Herranen et al. JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
- Development of Second-Generation CDK2 Inhibitors for the Prevention of Cisplatin-Induced Hearing Loss
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- Quinoxaline protects zebrafish lateral line hair cells from cisplatin and aminoglycosides damage
- (2018) Sonia M. Rocha Sanchez et al. Scientific Reports
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- (2018) Corné J. Kros et al. Cold Spring Harbor Perspectives in Medicine
- Cell-Specific Transcriptome Analysis Shows That Adult Pillar and Deiters' Cells Express Genes Encoding Machinery for Specializations of Cochlear Hair Cells
- (2018) Huizhan Liu et al. Frontiers in Molecular Neuroscience
- Transcriptomes of cochlear inner and outer hair cells from adult mice
- (2018) Yi Li et al. Scientific Data
- Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial
- (2017) David R Freyer et al. LANCET ONCOLOGY
- Allicin protects auditory hair cells and spiral ganglion neurons from cisplatin - Induced apoptosis
- (2017) Xianmin Wu et al. NEUROPHARMACOLOGY
- Age-related hearing loss: prevention of threshold declines, cell loss and apoptosis in spiral ganglion neurons
- (2016) Robert Frisina et al. Aging-US
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- (2016) David Planchard et al. LANCET ONCOLOGY
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- (2014) Shaloam Dasari et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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- (2014) Zhiyong Liu et al. PLoS One
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- Damage-Induced Activation of ERK1/2 in Cochlear Supporting Cells Is a Hair Cell Death-Promoting Signal That Depends on Extracellular ATP and Calcium
- (2008) M. Lahne et al. JOURNAL OF NEUROSCIENCE
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