Paeoniflorin protects spiral ganglion neurons from cisplatin-induced ototoxicity: Possible relation to PINK1/BAD pathway

Wnt Signaling Activates TP53-Induced Glycolysis and Apoptosis Regulator and Protects Against Cisplatin-Induced Spiral Ganglion Neuron Damage in the Mouse Cochlea

(2018) Wenwen Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

PINK1 Protects Auditory Hair Cells and Spiral Ganglion Neurons from Cisplatin-induced Ototoxicity via Inducing Autophagy and Inhibiting JNK Signaling Pathway

(2018) Qianqian Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Paeoniflorin reduces neomycin-induced ototoxicity in hair cells by suppression of reactive oxygen species generation and extracellularly regulated kinase signalization

(2018) Xiaoyu Yu et al.   TOXICOLOGY LETTERS

Paeoniflorin exerts neuroprotective effects against glutamate-induced PC12 cellular cytotoxicity by inhibiting apoptosis

(2017) Ahong Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

A Three-Dimensional Culture System with Matrigel Promotes Purified Spiral Ganglion Neuron Survival and Function In Vitro

(2017) Wenqing Yan et al.   MOLECULAR NEUROBIOLOGY

Allicin protects auditory hair cells and spiral ganglion neurons from cisplatin - Induced apoptosis

(2017) Xianmin Wu et al.   NEUROPHARMACOLOGY

Neuroprotection by Paeoniflorin in the MPTP mouse model of Parkinson's disease

(2017) Meizhu Zheng et al.   NEUROPHARMACOLOGY

Curcumin: A potentially powerful tool to reverse cisplatin-induced toxicity

(2017) Ramin Rezaee et al.   PHARMACOLOGICAL RESEARCH

Paeoniflorin ameliorates renal function in cyclophosphamide-induced mice via AMPK suppressed inflammation and apoptosis

(2016) Qiang Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Paeoniflorin inhibits doxorubicin-induced cardiomyocyte apoptosis by downregulating microRNA-1 expression

(2016) JIAN-ZHE LI et al.   Experimental and Therapeutic Medicine

The Three-Dimensional Culture System with Matrigel and Neurotrophic Factors Preserves the Structure and Function of Spiral Ganglion Neuron In Vitro

(2016) Gaoying Sun et al.   NEURAL PLASTICITY

Pink1 protects cortical neurons from thapsigargin-induced oxidative stress and neuronal apoptosis

(2015) Lin Li et al.   BIOSCIENCE REPORTS

Paeoniflorin inhibition of 6-hydroxydopamine-induced apoptosis in PC12 cells via suppressing reactive oxygen species-mediated PKCδ/NF-κB pathway

(2015) H. Dong et al.   NEUROSCIENCE

Paeoniflorin attenuates hepatic ischemia/reperfusion injury via anti-oxidative, anti-inflammatory and anti-apoptotic pathways

(2015) YE TAO et al.   Experimental and Therapeutic Medicine

Targeted Amelioration of Cisplatin-Induced Ototoxicity in Guinea Pigs

(2014) Shaulnie Mohan et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Inactivation of BAD by IKK Inhibits TNFα-Induced Apoptosis Independently of NF-κB Activation

(2013) Jie Yan et al.   CELL

Paeoniflorin, a Natural Neuroprotective Agent, Modulates Multiple Anti-Apoptotic and Pro-apoptotic Pathways in Differentiated PC12 Cells

(2013) Di Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Paeoniflorin protects against ANIT-induced cholestasis by ameliorating oxidative stress in rats

(2013) Yanling Zhao et al.   FOOD AND CHEMICAL TOXICOLOGY

Cisplatin-induced ototoxicity: Transporters playing a role in cisplatin toxicity

(2013) Sofia Waissbluth et al.   HEARING RESEARCH

Phosphatidylinositol 3 kinase/protein kinase B is responsible for the protection of paeoniflorin upon H2O2-induced neural progenitor cell injury

(2013) Y.-M. Wu et al.   NEUROSCIENCE

Paeoniflorin protects human EA.hy926 endothelial cells against gamma-radiation induced oxidative injury by activating the NF-E2-related factor 2/heme oxygenase-1 pathway

(2013) Jing Yu et al.   TOXICOLOGY LETTERS

Paeoniflorin protects myocardial cell from doxorubicin-induced apoptosis through inhibition of NADPH oxidase

(2012) Jian-Zhe Li et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Original article Protective effect of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via Bcl-2/Bax signal pathway

(2012) Rong Sun et al.   FOLIA NEUROPATHOLOGICA

Protective effects of peoniflorin against hydrogen peroxide-induced oxidative stress in human umbilical vein endothelial cells

(2011) Tao Chen et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

The Analgesic Effect of Paeoniflorin on Neonatal Maternal Separation–Induced Visceral Hyperalgesia in Rats

(2008) Xiao-jun Zhang et al.   JOURNAL OF PAIN

The anticancer drug cisplatin induces an intrinsic apoptotic pathway inside the inner ear

(2007) J R García-Berrocal et al.   BRITISH JOURNAL OF PHARMACOLOGY