Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM

A pneumonia outbreak associated with a new coronavirus of probable bat origin

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Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

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A new class of broadly neutralizing antibodies that target the glycan loop of Zika virus envelope protein

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Structural basis for RNA replication by the SARS-CoV-2 polymerase

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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

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Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies

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Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

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Structural basis of receptor recognition by SARS-CoV-2

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Cell entry mechanisms of SARS-CoV-2

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Site-specific glycan analysis of the SARS-CoV-2 spike

(2020) Yasunori Watanabe et al.   SCIENCE

Coronavirus membrane fusion mechanism offers a potential target for antiviral development

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Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

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A thermostable, closed SARS-CoV-2 spike protein trimer

(2020) Xiaoli Xiong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

(2020) Antoni G. Wrobel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct conformational states of SARS-CoV-2 spike protein

(2020) Yongfei Cai et al.   SCIENCE

Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures

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Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

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Structural basis for human coronavirus attachment to sialic acid receptors

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Intrinsic dynamics is evolutionarily optimized to enable allosteric behavior

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SWISS-MODEL: homology modelling of protein structures and complexes

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Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION

(2018) Takanori Nakane et al.   eLife

Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2

(2018) Wenfei Song et al.   PLoS Pathogens

goCTF: Geometrically optimized CTF determination for single-particle cryo-EM

(2018) Min Su   JOURNAL OF STRUCTURAL BIOLOGY

Structure of human TFIID and mechanism of TBP loading onto promoter DNA

(2018) Avinash B. Patel et al.   SCIENCE

Publisher Correction: Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

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New tools for automated high-resolution cryo-EM structure determination in RELION-3

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MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

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cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

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Addressing preferred specimen orientation in single-particle cryo-EM through tilting

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Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion

(2017) Alexandra C. Walls et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

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UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains

(2017) Yuan Yuan et al.   Nature Communications

A pipeline approach to single-particle processing inRELION

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Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding

(2016) Miao Gui et al.   CELL RESEARCH

High resolution single particle refinement in EMAN2.1

(2016) James M. Bell et al.   METHODS

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

(2016) Alexandra C. Walls et al.   NATURE

Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo-electron microscopy

(2016) Alexandra Walls et al.   PROTEIN SCIENCE

Structure, Function, and Evolution of Coronavirus Spike Proteins

(2016) Fang Li   Annual Review of Virology

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

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Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus

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Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement

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Deciphering key features in protein structures with the new ENDscript server

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Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

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