Sulforaphane induces colorectal cancer cell proliferation through Nrf2 activation in a p53-dependent manner

p53 and metabolism: from mechanism to therapeutics

(2018) Fernando M. Simabuco et al.   Oncotarget

The Roles of p53 in Mitochondrial Dynamics and Cancer Metabolism: The Pendulum between Survival and Death in Breast Cancer?

(2018) David Moulder et al.   Cancers

Protective Effect of Glyceollins in a Mouse Model of Dextran Sulfate Sodium-Induced Colitis

(2017) Hyelin Seo et al.   JOURNAL OF MEDICINAL FOOD

Suppression of Nrf2 Activity by Chestnut Leaf Extract Increases Chemosensitivity of Breast Cancer Stem Cells to Paclitaxel

(2017) Yaejin Woo et al.   Nutrients

Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress

(2017) Eri Kubo et al.   Scientific Reports

Dynamics of p53: A Master Decider of Cell Fate

(2017) Qingyin Luo et al.   Genes

The NRF2 transcription factor plays a dual role in colorectal cancer: A systematic review

(2017) C. Gonzalez-Donquiles et al.   PLoS One

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

Nrf2 protects mitochondrial decay by oxidative stress

(2016) Joshua Strom et al.   FASEB JOURNAL

Optimisation of enzymatic production of sulforaphane in broccoli sprouts and their total antioxidant activity at different growth and storage days

(2016) Ming Tian et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Redox Modulating NRF2: A Potential Mediator of Cancer Stem Cell Resistance

(2016) In-geun Ryoo et al.   Oxidative Medicine and Cellular Longevity

The Dual Roles of NRF2 in Cancer

(2016) Silvia Menegon et al.   TRENDS IN MOLECULAR MEDICINE

Dual roles of NRF2 in tumor prevention and progression: Possible implications in cancer treatment

(2015) Eui Jung Moon et al.   FREE RADICAL BIOLOGY AND MEDICINE

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant responses and cellular adjustments to oxidative stress

(2015) Cristina Espinosa-Diez et al.   Redox Biology

NRF2 and p53: Januses in cancer?

(2015) Barak Rotblat et al.   Oncotarget

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Oncogenic potential of Nrf2 and its principal target protein heme oxygenase-1

(2013) Hye-Kyung Na et al.   FREE RADICAL BIOLOGY AND MEDICINE

Enhancement of sulforaphane content in cabbage outer leaves using hybrid drying technique and stepwise change of drying temperature

(2013) Pitiporn Lekcharoenkul et al.   JOURNAL OF FOOD ENGINEERING

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Mitochondrial Dysfunction in Cancer

(2013) Michelle L. Boland et al.   Frontiers in Oncology

Does Nrf2 Contribute to p53-Mediated Control of Cell Survival and Death?

(2012) Weimin Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis

(2009) Maria A. Lebedeva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Mdm2-mediated ubiquitylation: p53 and beyond

(2009) J-C Marine et al.   CELL DEATH AND DIFFERENTIATION

Modulation of intracellular ROS levels by TIGAR controls autophagy

(2009) Karim Bensaad et al.   EMBO JOURNAL

Direct Interaction between Nrf2 and p21Cip1/WAF1 Upregulates the Nrf2-Mediated Antioxidant Response

(2009) Weimin Chen et al.   MOLECULAR CELL

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

(2008) X.-J. Wang et al.   CARCINOGENESIS

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1

(2008) Claude A. Piantadosi et al.   CIRCULATION RESEARCH

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL