Dynamics of p53: A Master Decider of Cell Fate

Finally, An Apoptosis-Targeting Therapeutic for Cancer

(2016) C. M. Croce et al.   CANCER RESEARCH

Cell-to-Cell Variation in p53 Dynamics Leads to Fractional Killing

(2016) Andrew L. Paek et al.   CELL

Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth

(2016) M Aggarwal et al.   CELL DEATH AND DIFFERENTIATION

p53 Reactivation by PRIMA-1Met (APR-246) sensitises V600E/KBRAF melanoma to vemurafenib

(2016) Mohammad Krayem et al.   EUROPEAN JOURNAL OF CANCER

Influence of microRNA-34a on proliferation, invasion and metastasis of HCT116 cells

(2016) Chunyan Li et al.   Molecular Medicine Reports

Full-length p53 tetramer bound to DNA and its quaternary dynamics

(2016) Ö Demir et al.   ONCOGENE

Modulation of the p53/MDM2 interplay by HAUSP inhibitors

(2016) Omid Tavana et al.   Journal of Molecular Cell Biology

STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation

(2015) Mao Ye et al.   Oncotarget

WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma

(2015) Mark Richter et al.   PLoS One

Lysine-specific modifications of p53: a matter of life and death?

(2015) Diana Marouco et al.   Oncotarget

Involvement of miR-605 and miR-34a in the DNA Damage Response Promotes Apoptosis Induction

(2014) Chun-Hong Zhou et al.   BIOPHYSICAL JOURNAL

MDM2-p53 Pathway in Hepatocellular Carcinoma

(2014) X. Meng et al.   CANCER RESEARCH

p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response

(2014) Hiroyoshi Hattori et al.   CELL CYCLE

Limiting the power of p53 through the ubiquitin proteasome pathway

(2014) Vinod Pant et al.   GENES & DEVELOPMENT

Ubiquitin-specific Peptidase 42 (USP42) Functions to Deubiquitylate Histones and Regulate Transcriptional Activity

(2014) Andreas K. Hock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters

(2014) Jayne Loughery et al.   NUCLEIC ACIDS RESEARCH

Palmdelphin, a novel target of p53 with Ser46 phosphorylation, controls cell death in response to DNA damage

(2014) N Dashzeveg et al.   Cell Death & Disease

The role of ubiquitin modification in the regulation of p53

(2013) Andreas K. Hock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

p28, A first in class peptide inhibitor of cop1 binding to p53

(2013) T Yamada et al.   BRITISH JOURNAL OF CANCER

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

Mechanisms That Enhance Sustainability of p53 Pulses

(2013) Jae Kyoung Kim et al.   PLoS One

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

A new target for TOR

(2012) Rachel David   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop

(2012) J Zhang et al.   ONCOGENE

A Two-Step Mechanism for Cell Fate Decision by Coordination of Nuclear and Mitochondrial p53 Activities

(2012) Xiao-Jun Tian et al.   PLoS One

p53 Dynamics Control Cell Fate

(2012) J. E. Purvis et al.   SCIENCE

miR-605joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress

(2011) Jiening Xiao et al.   EMBO JOURNAL

Stimulus-dependent dynamics of p53 in single cells

(2011) E. Batchelor et al.   Molecular Systems Biology

Two-phase dynamics of p53 in the DNA damage response

(2011) X.-P. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel regulator (USP10) of p53: Implications for tumor suppression and therapeutic targeting

(2010) Kelie M. Reece et al.   CANCER BIOLOGY & THERAPY

Basal Dynamics of p53 Reveal Transcriptionally Attenuated Pulses in Cycling Cells

(2010) Alexander Loewer et al.   CELL

USP10 Regulates p53 Localization and Stability by Deubiquitinating p53

(2010) Jian Yuan et al.   CELL

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Cell fate decision mediated by p53 pulses

(2009) X.-P. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Recurrent Initiation: A Mechanism for Triggering p53 Pulses in Response to DNA Damage

(2008) Eric Batchelor et al.   MOLECULAR CELL

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

(2008) F. M. Boeckler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

(2008) Jerry E. Chipuk et al.   TRENDS IN CELL BIOLOGY