From Multisensory Assessment to Functional Interpretation of Social Behavioral Phenotype in Transgenic Mouse Models for Autism Spectrum Disorders

Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD

(2020) Qian Chen et al.   NATURE NEUROSCIENCE

Somatosensorimotor and Odor Modification, Along with Serotonergic Processes Underlying the Social Deficits in BTBR T+ Itpr3tf/J and BALB/cJ Mouse Models of Autism

(2020) Hiroyuki Arakawa   NEUROSCIENCE

Behavioral Tests for Mouse Models of Autism: An Argument for the Inclusion of Cerebellum-Controlled Motor Behaviors

(2020) Dana H. Simmons et al.   NEUROSCIENCE

Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception

(2020) Nicole L. Neubarth et al.   SCIENCE

Sex-Dependent Sensory Phenotypes and Related Transcriptomic Expression Profiles Are Differentially Affected by Angelman Syndrome

(2019) Lee Koyavski et al.   MOLECULAR NEUROBIOLOGY

Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models

(2019) Lauren L. Orefice et al.   CELL

A Light Touch on Sociability

(2019) Nuria Domínguez-Iturza et al.   CELL

Developmental milestones and behavior of infant rats: The role of sensory input from whiskers

(2019) Kirill Smirnov et al.   BEHAVIOURAL BRAIN RESEARCH

Social creatures: Model animal systems for studying the neuroendocrine mechanisms of social behaviour

(2019) Kelly J. Robinson et al.   JOURNAL OF NEUROENDOCRINOLOGY

Rescue-like Behaviour in Mice is Mediated by Their Interest in the Restraint Tool

(2019) Hiroshi Ueno et al.   Scientific Reports

Oxytocin is a principal hormone that exerts part of its effects by active fragments

(2019) Kerstin Uvnäs Moberg et al.   MEDICAL HYPOTHESES

Mechanisms of Tactile Sensory Phenotypes in Autism: Current Understanding and Future Directions for Research

(2019) Melanie D. Schaffler et al.   Current Psychiatry Reports

Ethological approach to social isolation effects in behavioral studies of laboratory rodents

(2018) Hiroyuki Arakawa   BEHAVIOURAL BRAIN RESEARCH

Whisker dependent responsiveness of C57BL/6J mice to different behavioral test paradigms

(2018) Seenu Haridas et al.   BEHAVIOURAL BRAIN RESEARCH

Neonatal whisker trimming in WAG/Rij rat pups causes developmental delay, encourages maternal care and affects exploratory activity in adulthood

(2018) Kirill Smirnov et al.   BRAIN RESEARCH BULLETIN

Corrected Prevalence of Autism Spectrum Disorder Among US Children and Adolescents

(2018) Guifeng Xu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability

(2018) John M. Dawes et al.   NEURON

Analysis of Social Process in Two Inbred Strains of Male Mice: A Predominance of Contact-Based Investigation in BALB/c Mice

(2018) Hiroyuki Arakawa   NEUROSCIENCE

Ethological and multi-behavioral analysis of learning and memory performance in laboratory rodent models

(2018) Hiroyuki Arakawa et al.   NEUROSCIENCE RESEARCH

Current Enlightenment About Etiology and Pharmacological Treatment of Autism Spectrum Disorder

(2018) Nermin Eissa et al.   Frontiers in Neuroscience

Dendritic Spines in Early Postnatal Fragile X Mice Are Insensitive to Novel Sensory Experience

(2018) Erica D. Arroyo et al.   JOURNAL OF NEUROSCIENCE

Enhanced Nociception in Angelman Syndrome Model Mice

(2017) Eric S. McCoy et al.   JOURNAL OF NEUROSCIENCE

Tactile Defensiveness and Impaired Adaptation of Neuronal Activity in the Fmr1 Knock-Out Mouse Model of Autism

(2017) Cynthia X. He et al.   JOURNAL OF NEUROSCIENCE

Sensory perception in autism

(2017) Caroline E. Robertson et al.   NATURE REVIEWS NEUROSCIENCE

Translating dynamic defense patterns from rodents to people

(2017) D. Caroline Blanchard   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Neuronal cytoskeletal gene dysregulation and mechanical hypersensitivity in a rat model of Rett syndrome

(2017) Aritra Bhattacherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs

(2016) Lauren L. Orefice et al.   CELL

From classic ethology to modern neuroethology: overcoming the three biases in social behavior research

(2016) Noga Zilkha et al.   CURRENT OPINION IN NEUROBIOLOGY

Autism: Will vitamin D supplementation during pregnancy and early childhood reduce the recurrence rate of autism in newborn siblings?

(2016) G. Stubbs et al.   MEDICAL HYPOTHESES

SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons

(2016) Qingjian Han et al.   NEURON

Neonatal Whisker Trimming Impairs Fear/Anxiety-Related Emotional Systems of the Amygdala and Social Behaviors in Adult Mice

(2016) Hitomi Soumiya et al.   PLoS One

Genetic and non-genetic animal models for autism spectrum disorders (ASD)

(2016) Zivanit Ergaz et al.   REPRODUCTIVE TOXICOLOGY

Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism

(2016) Xiaoming Wang et al.   Nature Communications

The Emerging Picture of Autism Spectrum Disorder: Genetics and Pathology

(2015) Jason A. Chen et al.   Annual Review of Pathology-Mechanisms of Disease

Role of whiskers in sensorimotor development of C57BL/6 mice

(2015) Hiroyuki Arakawa et al.   BEHAVIOURAL BRAIN RESEARCH

A Mechanistic Link between Olfaction and Autism Spectrum Disorder

(2015) Liron Rozenkrantz et al.   CURRENT BIOLOGY

Behavioral phenotypes of genetic mouse models of autism

(2015) T. M. Kazdoba et al.   GENES BRAIN AND BEHAVIOR

Central oxytocin regulates social familiarity and scent marking behavior that involves amicable odor signals between male mice

(2015) Hiroyuki Arakawa et al.   PHYSIOLOGY & BEHAVIOR

Genetic dissection of pheromone processing reveals main olfactory system-mediated social behaviors in mice

(2015) Tomohiko Matsuo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prenatal factors associated with autism spectrum disorder (ASD)

(2015) A. Ornoy et al.   REPRODUCTIVE TOXICOLOGY

Detecting autonomic response to pain in Rett syndrome

(2015) Heather M. O’Leary et al.   Developmental Neurorehabilitation

Functional and structural deficits at accumbens synapses in a mouse model of Fragile X

(2015) Daniela Neuhofer et al.   Frontiers in Cellular Neuroscience

Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders

(2015) Janine M LaSalle et al.   Epigenomics

Mapping Social Behavior-Induced Brain Activation at Cellular Resolution in the Mouse

(2015) Yongsoo Kim et al.   Cell Reports

Ultrastructural analyses in the hippocampus CA1 field in Shank3-deficient mice

(2015) Neha Uppal et al.   Molecular Autism

Pre- and Perinatal Risk Factors for Autism Spectrum Disorder in a New Jersey Cohort

(2014) Lauren A. Maramara et al.   JOURNAL OF CHILD NEUROLOGY

Impaired tactile processing in children with autism spectrum disorder

(2014) Nicolaas A. J. Puts et al.   JOURNAL OF NEUROPHYSIOLOGY

Thalamic NMDA Receptor Function Is Necessary for Patterning of the Thalamocortical Somatosensory Map and for Sensorimotor Behaviors

(2014) H. Arakawa et al.   JOURNAL OF NEUROSCIENCE

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1 −/y mice

(2014) Yu Zhang et al.   NATURE NEUROSCIENCE

Discriminative and Affective Touch: Sensing and Feeling

(2014) Francis McGlone et al.   NEURON

Recent advances in animal model experimentation in autism research

(2013) Mousumi Tania et al.   ACTA NEUROPSYCHIATRICA

Animal models of social avoidance and social fear

(2013) Iulia Toth et al.   CELL AND TISSUE RESEARCH

Temporal and Mosaic Tsc1 Deletion in the Developing Thalamus Disrupts Thalamocortical Circuitry, Neural Function, and Behavior

(2013) Elizabeth A. Normand et al.   NEURON

How do children with autism spectrum disorders express pain? A comparison with developmentally delayed and typically developing children

(2013) Cécile Rattaz et al.   PAIN

Olfaction in the Autism Spectrum

(2013) Sara A Galle et al.   PERCEPTION

Autobiographical Accounts of Sensing in Asperger Syndrome and High-Functioning Autism

(2012) Marie Elwin et al.   ARCHIVES OF PSYCHIATRIC NURSING

Children With Autism Show Reduced Somatosensory Response: An MEG Study

(2012) Elysa J. Marco et al.   Autism Research

Olfactory classical conditioning in neonatal mouse pups using thermal stimuli

(2012) Bieke Bollen et al.   BEHAVIOURAL BRAIN RESEARCH

The BTBR T+tf/J mouse model for autism spectrum disorders–in search of biomarkers

(2012) Ksenia Z. Meyza et al.   BEHAVIOURAL BRAIN RESEARCH

Autism spectrum disorders

(2012) Alexis Tchaconas et al.   CURRENT OPINION IN PEDIATRICS

Female Mecp2+/− mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies

(2012) Rodney C. Samaco et al.   HUMAN MOLECULAR GENETICS

Of mice and monkeys: using non-human primate models to bridge mouse- and human-based investigations of autism spectrum disorders

(2012) Karli K Watson et al.   Journal of Neurodevelopmental Disorders

Autism-related deficits via dysregulated eIF4E-dependent translational control

(2012) Christos G. Gkogkas et al.   NATURE

Of Mice, Birds, and Men: The Mouse Ultrasonic Song System Has Some Features Similar to Humans and Song-Learning Birds

(2012) Gustavo Arriaga et al.   PLoS One

Autistic traits are associated with diminished neural response to affective touch

(2012) Avery C. Voos et al.   Social Cognitive and Affective Neuroscience

The social brain in psychiatric and neurological disorders

(2012) Daniel P. Kennedy et al.   TRENDS IN COGNITIVE SCIENCES

What does CNTNAP2 reveal about autism spectrum disorder?

(2012) Olga Peñagarikano et al.   TRENDS IN MOLECULAR MEDICINE

Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex

(2012) Atsushi Sato et al.   Nature Communications

New Models for Considering the Role of Medication in the Treatment and Elucidation of the Etiology of Autism

(2012) Sharon Smile et al.   Current Psychiatry Reports

Animal Models of Psychiatric Disorders That Reflect Human Copy Number Variation

(2012) Jun Nomura et al.   NEURAL PLASTICITY

Sensory deprivation during early development causes an increased exploratory behavior in a whisker-dependent decision task

(2012) Stylianos Papaioannou et al.   Brain and Behavior

Pre-, peri- and neonatal risk factors for autism

(2011) VINCENT GUINCHAT et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

(2011) Joachim Hallmayer   ARCHIVES OF GENERAL PSYCHIATRY

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

(2011) Hsien-Sung Huang et al.   NATURE

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Testing declarative memory in laboratory rats and mice using the nonconditioned social discrimination procedure

(2011) Mario Engelmann et al.   Nature Protocols

From models to mechanisms: Odorant communication as a key determinant of social behavior in rodents during illness-associated states

(2011) Hiroyuki Arakawa et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

BTBR T+tf/J mice: Autism-relevant behaviors and reduced fractone-associated heparan sulfate

(2011) D. Caroline Blanchard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Perinatal and Neonatal Risk Factors for Autism: A Comprehensive Meta-analysis

(2011) H. Gardener et al.   PEDIATRICS

Empathy and Pro-Social Behavior in Rats

(2011) I. B.-A. Bartal et al.   SCIENCE

Genetics of autism spectrum disorders

(2011) Daniel H. Geschwind   TRENDS IN COGNITIVE SCIENCES

Behavior and neuropsychiatric manifestations in Angelman syndrome

(2011) Bernard Dan   Neuropsychiatric Disease and Treatment

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

(2011) Ozlem Bozdagi et al.   Molecular Autism

Fetal Valproate Syndrome: Clinical and Neuro-developmental Features in Two Sibling Pairs

(2010) Arnold L. Christianson et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Clinical and genetic aspects of Angelman syndrome

(2010) Charles A Williams et al.   GENETICS IN MEDICINE

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Different importance of the volatile and non-volatile fractions of an olfactory signature for individual social recognition in rats versus mice and short-term versus long-term memory

(2010) Julia Noack et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Oxytocin and vasopressin in the medial amygdala differentially modulate approach and avoidance behavior toward illness-related social odor

(2010) H. Arakawa et al.   NEUROSCIENCE

Risk assessment as an evolved threat detection and analysis process

(2010) D. Caroline Blanchard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Altered Functional Connectivity in Frontal Lobe Circuits Is Associated with Variation in the Autism Risk Gene CNTNAP2

(2010) A. A. Scott-Van Zeeland et al.   Science Translational Medicine

Neonatal whisker trimming causes long-lasting changes in structure and function of the somatosensory system

(2009) Li-Jen Lee et al.   EXPERIMENTAL NEUROLOGY

How Can Early, Intensive Training Help a Genetic Disorder?

(2009) William A. Altemeier et al.   PEDIATRIC ANNALS

Epidemiology of Pervasive Developmental Disorders

(2009) Eric Fombonne   PEDIATRIC RESEARCH

Prevalence of Parent-Reported Diagnosis of Autism Spectrum Disorder Among Children in the US, 2007

(2009) M. D. Kogan et al.   PEDIATRICS

Social psychology as a natural kind

(2009) Jason P. Mitchell   TRENDS IN COGNITIVE SCIENCES

Vision in autism spectrum disorders

(2009) David R. Simmons et al.   VISION RESEARCH

Criteria for validating mouse models of psychiatric diseases

(2008) Kathryn K. Chadman et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Visual Abilities and Sensory Differences in a Person with Autism

(2008) Temple Grandin   BIOLOGICAL PSYCHIATRY

Copy-number variations associated with neuropsychiatric conditions

(2008) Edwin H. Cook Jr et al.   NATURE

Advances in autism genetics: on the threshold of a new neurobiology

(2008) Brett S. Abrahams et al.   NATURE REVIEWS GENETICS

Behavioral Phenotyping Strategies for Mutant Mice

(2008) Jacqueline N. Crawley   NEURON

Scent marking behavior as an odorant communication in mice

(2008) Hiroyuki Arakawa et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Behavioural and Developmental Interventions for Autism Spectrum Disorder: A Clinical Systematic Review

(2008) Maria B. Ospina et al.   PLoS One

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR