Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex

Sirolimus Therapy for Angiomyolipoma in Tuberous Sclerosis and Sporadic Lymphangioleiomyomatosis: A Phase 2 Trial

(2011) D. M. Davies et al.   CLINICAL CANCER RESEARCH

Mutations causing syndromic autism define an axis of synaptic pathophysiology

(2011) Benjamin D. Auerbach et al.   NATURE

Identification of risk factors for autism spectrum disorders in tuberous sclerosis complex

(2011) A. L. Numis et al.   NEUROLOGY

The Quantitative Nature of Autistic Social Impairment

(2011) JOHN N. CONSTANTINO   PEDIATRIC RESEARCH

Epilepsy and Tsc2 Haploinsufficiency Lead to Autistic-Like Social Deficit Behaviors in Rats

(2010) Robert Waltereit et al.   BEHAVIOR GENETICS

Genetic causes of syndromic and non-syndromic autism

(2010) AHMET O CAGLAYAN   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of Tuberous Sclerosis Complex

(2010) L.-H. Zeng et al.   HUMAN MOLECULAR GENETICS

Dysregulation of mTOR Signaling in Fragile X Syndrome

(2010) A. Sharma et al.   JOURNAL OF NEUROSCIENCE

Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice

(2010) D Ehninger et al.   MOLECULAR PSYCHIATRY

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Targeted treatments for cognitive and neurodevelopmental disorders in tuberous sclerosis complex

(2010) Petrus J. Vries   Neurotherapeutics

Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis

(2010) Darcy A. Krueger et al.   NEW ENGLAND JOURNAL OF MEDICINE

GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism

(2010) Marjelo A. Mines et al.   PLoS One

Evaluation of Pax6 Mutant Rat as a Model for Autism

(2010) Toshiko Umeda et al.   PLoS One

Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders

(2010) Dan Ehninger et al.   TRENDS IN MOLECULAR MEDICINE

Characteristics and Concordance of Autism Spectrum Disorders Among 277 Twin Pairs

(2009) Rebecca E. Rosenberg et al.   ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE

Social deficits, stereotypy and early emergence of repetitive behavior in the C58/J inbred mouse strain

(2009) Bryce C. Ryan et al.   BEHAVIOURAL BRAIN RESEARCH

Pharmacological Inhibition of mTORC1 Suppresses Anatomical, Cellular, and Behavioral Abnormalities in Neural-Specific Pten Knock-Out Mice

(2009) J. Zhou et al.   JOURNAL OF NEUROSCIENCE

Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome.

(2008) Caitlyn H. McNaughton et al.   BEHAVIORAL NEUROSCIENCE

Antipsychotics in the treatment of autism

(2008) David J. Posey et al.   JOURNAL OF CLINICAL INVESTIGATION

The Neurogenesis-Controlling Factor, Pax6, Inhibits Proliferation and Promotes Maturation in Murine Astrocytes

(2008) K. Sakurai et al.   JOURNAL OF NEUROSCIENCE

Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis

(2008) Dan Ehninger et al.   NATURE MEDICINE

Advances in autism genetics: on the threshold of a new neurobiology

(2008) Brett S. Abrahams et al.   NATURE REVIEWS GENETICS

Elevated glycogen synthase kinase-3 activity in Fragile X mice: Key metabolic regulator with evidence for treatment potential

(2008) Wenzhong William Min et al.   NEUROPHARMACOLOGY

The ‘Fractionable Autism Triad’: A Review of Evidence from Behavioural, Genetic, Cognitive and Neural Research

(2008) Francesca Happé et al.   NEUROPSYCHOLOGY REVIEW