Behavioral phenotypes of genetic mouse models of autism

Recent Advances in Autism Research as Reflected in DSM-5 Criteria for Autism Spectrum Disorder

(2015) Catherine Lord et al.   Annual Review of Clinical Psychology

16p11.2 Deletion Syndrome Mice Display Sensory and Ultrasonic Vocalization Deficits During Social Interactions

(2015) Mu Yang et al.   Autism Research

Fragile X mental retardation protein: A paradigm for translational control by RNA-binding proteins

(2015) Eileen Chen et al.   BIOCHIMIE

An Early Postnatal Oxytocin Treatment Prevents Social and Learning Deficits in Adult Mice Deficient for Magel2, a Gene Involved in Prader-Willi Syndrome and Autism

(2015) Hamid Meziane et al.   BIOLOGICAL PSYCHIATRY

Autism spectrum disorders: from genes to neurobiology

(2015) A Jeremy Willsey et al.   CURRENT OPINION IN NEUROBIOLOGY

Dravet syndrome in Sweden: a population-based study

(2015) Cecilia Rosander et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Decreased aggression and increased repetitive behavior inPtenhaploinsufficient mice

(2015) A. E. Clipperton-Allen et al.   GENES BRAIN AND BEHAVIOR

Dysregulated brain immunity and neurotrophin signaling in Rett syndrome and autism spectrum disorders

(2015) Theoharis C. Theoharides et al.   JOURNAL OF NEUROIMMUNOLOGY

Gene hunting in autism spectrum disorder: on the path to precision medicine

(2015) Daniel H Geschwind et al.   LANCET NEUROLOGY

Excess of rare, inherited truncating mutations in autism

(2015) Niklas Krumm et al.   NATURE GENETICS

Whole-genome sequencing of quartet families with autism spectrum disorder

(2015) Ryan K C Yuen et al.   NATURE MEDICINE

Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion

(2015) Di Tian et al.   NATURE NEUROSCIENCE

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

(2015) J L Silverman et al.   NEUROPSYCHOPHARMACOLOGY

Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism

(2015) Olga Peñagarikano et al.   Science Translational Medicine

The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment

(2015) Justin Cotney et al.   Nature Communications

No Evidence for Association of Autism with Rare Heterozygous Point Mutations in Contactin-Associated Protein-Like 2 (CNTNAP2), or in Other Contactin-Associated Proteins or Contactins

(2015) John D. Murdoch et al.   PLoS Genetics

The Interplay between Synaptic Activity and Neuroligin Function in the CNS

(2015) Xiaoge Hu et al.   Biomed Research International

The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genes

(2015) B Wilkinson et al.   Translational Psychiatry

Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

(2014) Dalila Pinto et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association ofCDH11with non-syndromic ASD

(2014) An Crepel et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Behavioral analysis of male and female Fmr1 knockout mice on C57BL/6 background

(2014) Qi Ding et al.   BEHAVIOURAL BRAIN RESEARCH

De novo SCN2A splice site mutation in a boy with Autism spectrum disorder

(2014) Teresa Tavassoli et al.   BMC Medical Genetics

Anti-brain antibodies are associated with more severe cognitive and behavioral profiles in Italian children with Autism Spectrum Disorder

(2014) I.S. Piras et al.   BRAIN BEHAVIOR AND IMMUNITY

Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development

(2014) Raphael Bernier et al.   CELL

Absence of strong strain effects in behavioral analyses of Shank3-deficient mice

(2014) E. Drapeau et al.   Disease Models & Mechanisms

Pten haploinsufficient mice show broad brain overgrowth but selective impairments in autism-relevant behavioral tests

(2014) Amy E. Clipperton-Allen et al.   HUMAN MOLECULAR GENETICS

The Familial Risk of Autism

(2014) Sven Sandin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism

(2014) T W Frazier et al.   MOLECULAR PSYCHIATRY

Integrated systems analysis reveals a molecular network underlying autism spectrum disorders

(2014) J. Li et al.   Molecular Systems Biology

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

The contribution of de novo coding mutations to autism spectrum disorder

(2014) Ivan Iossifov et al.   NATURE

Refining analyses of copy number variation identifies specific genes associated with developmental delay

(2014) Bradley P Coe et al.   NATURE GENETICS

Most genetic risk for autism resides with common variation

(2014) Trent Gaugler et al.   NATURE GENETICS

Disentangling the heterogeneity of autism spectrum disorder through genetic findings

(2014) Shafali S. Jeste et al.   Nature Reviews Neurology

Enhancement of Inhibitory Neurotransmission by GABA A Receptors Having α 2,3 -Subunits Ameliorates Behavioral Deficits in a Mouse Model of Autism

(2014) Sung Han et al.   NEURON

Neurodevelopment and the Origins of Brain Disorders

(2014)   NEUROPSYCHOPHARMACOLOGY

Reduced Phenotypic Severity Following Adeno-Associated Virus-Mediated Fmr1 Gene Delivery in Fragile X Mice

(2014) Shervin Gholizadeh et al.   NEUROPSYCHOPHARMACOLOGY

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments

(2014) Claire S. Leblond et al.   PLoS Genetics

New strategies and findings for behavioral interventions in autism spectrum disorders

(2013) Catherine Lord et al.   Annals of the New York Academy of Sciences

Brain-Reactive Antibodies and Disease

(2013) B. Diamond et al.   Annual Review of Immunology

Inhibition of histone deacetylase in utero causes sociability deficits in postnatal mice

(2013) Randal X. Moldrich et al.   BEHAVIOURAL BRAIN RESEARCH

d-Cycloserine improves sociability in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders with altered Ras/Raf/ERK1/2 signaling

(2013) Jessica A. Burket et al.   BRAIN RESEARCH BULLETIN

Rapamycin improves sociability in the BTBR T+Itpr3tf/J mouse model of autism spectrum disorders

(2013) Jessica A. Burket et al.   BRAIN RESEARCH BULLETIN

Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism

(2013) Neelroop N. Parikshak et al.   CELL

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome

(2013) Christine S Cheah et al.   Channels

The promising trajectory of autism therapeutics discovery

(2013) Jill L. Silverman et al.   DRUG DISCOVERY TODAY

A Danish population-based twin study on autism spectrum disorders

(2013) Claudia Nordenbæk et al.   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Shining a light on CNTNAP2: complex functions to complex disorders

(2013) Pedro Rodenas-Cuadrado et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Developing new pharmacotherapies for autism

(2013) C. Ecker et al.   JOURNAL OF INTERNAL MEDICINE

Loss of Predominant Shank3 Isoforms Results in Hippocampus-Dependent Impairments in Behavior and Synaptic Transmission

(2013) M. Kouser et al.   JOURNAL OF NEUROSCIENCE

Brain-reactive IgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder

(2013) L Brimberg et al.   MOLECULAR PSYCHIATRY

Progress toward treatments for synaptic defects in autism

(2013) Richard Delorme et al.   NATURE MEDICINE

Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons

(2013) Jocelyn F Krey et al.   NATURE NEUROSCIENCE

A Matter of Balance: Role of Neurexin and Neuroligin at the Synapse

(2013) Marie Louise Bang et al.   NEUROCHEMICAL RESEARCH

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Chronic and Acute Intranasal Oxytocin Produce Divergent Social Effects in Mice

(2013) Huiping Huang et al.   NEUROPSYCHOPHARMACOLOGY

Altered Social Behaviours in Neurexin 1α Knockout Mice Resemble Core Symptoms in Neurodevelopmental Disorders

(2013) Hannah Mary Grayton et al.   PLoS One

Defining the Contribution of CNTNAP2 to Autism Susceptibility

(2013) Srirangan Sampath et al.   PLoS One

Using genetic findings in autism for the development of new pharmaceutical compounds

(2013) Jacob A. S. Vorstman et al.   PSYCHOPHARMACOLOGY

Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: current status and future perspectives

(2013) Martien J. Kas et al.   PSYCHOPHARMACOLOGY

Insulin-like growth factor-1 rescues synaptic and motor deficits in a mouse model of autism and developmental delay

(2013) Ozlem Bozdagi et al.   Molecular Autism

Autism-specific maternal autoantibodies recognize critical proteins in developing brain

(2013) D Braunschweig et al.   Translational Psychiatry

SHANK1 Deletions in Males with Autism Spectrum Disorder

(2012) Daisuke Sato et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Global Prevalence of Autism and Other Pervasive Developmental Disorders

(2012) Mayada Elsabbagh et al.   Autism Research

Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism

(2012) Ahmed El-Kordi et al.   BEHAVIOURAL BRAIN RESEARCH

Developmental delays and reduced pup ultrasonic vocalizations but normal sociability in mice lacking the postsynaptic cell adhesion protein neuroligin2

(2012) Markus Wöhr et al.   BEHAVIOURAL BRAIN RESEARCH

Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation

(2012) Jacob J. Michaelson et al.   CELL

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses

(2012) Dilja D Krueger et al.   CURRENT OPINION IN NEUROBIOLOGY

Prevalence of SHANK3 variants in patients with different subtypes of autism spectrum disorders

(2012) Luigi Boccuto et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Reduction of BDNF expression inFmr1knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits

(2012) M. Uutela et al.   GENES BRAIN AND BEHAVIOR

Reduced Excitatory Neurotransmission and Mild Autism-Relevant Phenotypes in Adolescent Shank3 Null Mutant Mice

(2012) M. Yang et al.   JOURNAL OF NEUROSCIENCE

Effects of a Brief Early Start Denver Model (ESDM)–Based Parent Intervention on Toddlers at Risk for Autism Spectrum Disorders: A Randomized Controlled Trial

(2012) Sally J. Rogers et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Autistic-like behaviour in Scn1a +/− mice and rescue by enhanced GABA-mediated neurotransmission

(2012) Sung Han et al.   NATURE

Autism-related deficits via dysregulated eIF4E-dependent translational control

(2012) Christos G. Gkogkas et al.   NATURE

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

(2012) Hyejung Won et al.   NATURE

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

(2012) Peter T. Tsai et al.   NATURE

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

Rate of de novo mutations and the importance of father’s age to disease risk

(2012) Augustine Kong et al.   NATURE

Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex

(2012) R. Michelle Reith et al.   NEUROBIOLOGY OF DISEASE

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

(2012) Aubin Michalon et al.   NEURON

Class I histone deacetylase inhibition ameliorates social cognition and cell adhesion molecule plasticity deficits in a rodent model of autism spectrum disorder

(2012) Andrew G. Foley et al.   NEUROPHARMACOLOGY

AMPAKINE enhancement of social interaction in the BTBR mouse model of autism

(2012) J.L. Silverman et al.   NEUROPHARMACOLOGY

Low sociability in BTBR T+tf/J mice is independent of partner strain

(2012) Mu Yang et al.   PHYSIOLOGY & BEHAVIOR

Deletion of Glutamate Delta-1 Receptor in Mouse Leads to Aberrant Emotional and Social Behaviors

(2012) Roopali Yadav et al.   PLoS One

Dimerization of postsynaptic neuroligin drives synaptic assembly via transsynaptic clustering of neurexin

(2012) S. L. Shipman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

(2012) J. Veenstra-VanderWeele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling

(2012) E. C. Budreck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism

(2012) S. J. Baudouin et al.   SCIENCE

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABAB Receptors with Arbaclofen

(2012) C. Henderson et al.   Science Translational Medicine

Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism

(2012) J. L. Silverman et al.   Science Translational Medicine

Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders

(2012) Will Spooren et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Principles of Translational Control: An Overview

(2012) J. W. B. Hershey et al.   Cold Spring Harbor Perspectives in Biology

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Prevalence of Autism Spectrum Disorders in a Total Population Sample

(2011) Young Shin Kim et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

(2011) Joachim Hallmayer   ARCHIVES OF GENERAL PSYCHIATRY

Behavioral profiles of mouse models for autism spectrum disorders

(2011) Elodie Ey et al.   Autism Research

Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses

(2011) Corinne M. Spencer et al.   Autism Research

Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS)

(2011) Surabi Veeraragavan et al.   BEHAVIOURAL BRAIN RESEARCH

Expanding the clinical spectrum associated with defects in CNTNAP2 and NRXN1

(2011) Anne Gregor et al.   BMC Medical Genetics

Absence of CNTNAP2 Leads to Epilepsy, Neuronal Migration Abnormalities, and Core Autism-Related Deficits

(2011) Olga Peñagarikano et al.   CELL

Autism spectrum disorders—A genetics review

(2011) Judith H Miles   GENETICS IN MEDICINE

The oxytocin system in drug discovery for autism: Animal models and novel therapeutic strategies

(2011) Meera E. Modi et al.   HORMONES AND BEHAVIOR

Inherited and de novo SHANK2 variants associated with autism spectrum disorder impair neuronal morphogenesis and physiology

(2011) Simone Berkel et al.   HUMAN MOLECULAR GENETICS

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

(2011) Xiaoming Wang et al.   HUMAN MOLECULAR GENETICS

Mutations causing syndromic autism define an axis of synaptic pathophysiology

(2011) Benjamin D. Auerbach et al.   NATURE

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

(2011) Brian J O'Roak et al.   NATURE GENETICS

Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin

(2011) Itzamarie Chévere-Torres et al.   NEUROBIOLOGY OF DISEASE

Genetic-Background Modulation of Core and Variable Autistic-Like Symptoms in Fmr1 Knock-Out Mice

(2011) Susanna Pietropaolo et al.   PLoS One

Communication Impairments in Mice Lacking Shank1: Reduced Levels of Ultrasonic Vocalizations and Scent Marking Behavior

(2011) Markus Wöhr et al.   PLoS One

Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

(2011) M. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

(2011) Andreas M. Grabrucker et al.   TRENDS IN CELL BIOLOGY

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

(2011) Ozlem Bozdagi et al.   Molecular Autism

Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly

(2010) Kim L. McBride et al.   Autism Research

Sociability and motor functions in Shank1 mutant mice

(2010) Jill L. Silverman et al.   BRAIN RESEARCH

Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism

(2010) M. Wöhr et al.   GENES BRAIN AND BEHAVIOR

Unusual repertoire of vocalizations in adult BTBR T+tf/J mice during three types of social encounters

(2010) M. L. Scattoni et al.   GENES BRAIN AND BEHAVIOR

Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication

(2010) J. Fischer et al.   GENES BRAIN AND BEHAVIOR

Autism Spectrum Disorders in Tuberous Sclerosis: Pathogenetic Pathways and Implications for Treatment

(2010) Paolo Curatolo et al.   JOURNAL OF CHILD NEUROLOGY

Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior

(2010) J. Blundell et al.   JOURNAL OF NEUROSCIENCE

Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice

(2010) D Ehninger et al.   MOLECULAR PSYCHIATRY

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

(2010) Simone Berkel et al.   NATURE GENETICS

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism

(2010) J.L. Silverman et al.   NEUROSCIENCE

De novo mutations in the gene encoding the synaptic scaffolding proteinSHANK3in patients ascertained for schizophrenia

(2010) Julie Gauthier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders

(2010) Dan Ehninger et al.   TRENDS IN MOLECULAR MEDICINE

Altered neuroligin expression is involved in social deficits in a mouse model of the fragile X syndrome

(2009) Regina Dahlhaus et al.   BEHAVIOURAL BRAIN RESEARCH

A complex interplay between Akt, TSC2 and the two mTOR complexes: Figure 1

(2009) Jingxiang Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A synaptic trek to autism

(2009) Thomas Bourgeron   CURRENT OPINION IN NEUROBIOLOGY

Gene, brain, and behavior relationships in fragile X syndrome: Evidence from neuroimaging studies

(2009) Amy A. Lightbody et al.   Developmental Disabilities Research Reviews

Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit

(2009) K. Radyushkin et al.   GENES BRAIN AND BEHAVIOR

The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly

(2009) Elizabeth A Varga et al.   GENETICS IN MEDICINE

Pharmacological Inhibition of mTORC1 Suppresses Anatomical, Cellular, and Behavioral Abnormalities in Neural-Specific Pten Knock-Out Mice

(2009) J. Zhou et al.   JOURNAL OF NEUROSCIENCE

Common genetic variants on 5p14.1 associate with autism spectrum disorders

(2009) Kai Wang et al.   NATURE

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

(2009) Joseph T. Glessner et al.   NATURE

Disruption of CNTNAP2 and additional structural genome changes in a boy with speech delay and autism spectrum disorder

(2009) Martin Poot et al.   NEUROGENETICS

Dissociation of social and nonsocial anxiety in a mouse model of fragile X syndrome

(2009) Zhong-Hua Liu et al.   NEUROSCIENCE LETTERS

Epidemiology of Pervasive Developmental Disorders

(2009) Eric Fombonne   PEDIATRIC RESEARCH

Association and Mutation Analyses of 16p11.2 Autism Candidate Genes

(2009) Ravinesh A. Kumar et al.   PLoS One

Haploinsufficiency forPtenandSerotonin transportercooperatively influences brain size and social behavior

(2009) Damon T. Page et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse neurexin-1  deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments

(2009) M. R. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Analyses of Exonic Copy Number Variants in a Family-Based Study Point to Novel Autism Susceptibility Genes

(2009) Maja Bucan et al.   PLoS Genetics

Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene

(2008) Maricela Alarcón et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural Variation of Chromosomes in Autism Spectrum Disorder

(2008) Christian R. Marshall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Common Genetic Variant in the Neurexin Superfamily Member CNTNAP2 Increases Familial Risk of Autism

(2008) Dan E. Arking et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular Cytogenetic Analysis and Resequencing of Contactin Associated Protein-Like 2 in Autism Spectrum Disorders

(2008) Betul Bakkaloglu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Novel de novo SHANK3 mutation in autistic patients

(2008) Julie Gauthier et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice

(2008) Kathryn K. Chadman et al.   Autism Research

Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene.

(2008) Corinne M. Spencer et al.   BEHAVIORAL NEUROSCIENCE

Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome.

(2008) Caitlyn H. McNaughton et al.   BEHAVIORAL NEUROSCIENCE

Social approach and repetitive behavior in eleven inbred mouse strains

(2008) Sheryl S. Moy et al.   BEHAVIOURAL BRAIN RESEARCH

Development of a mouse test for repetitive, restricted behaviors: Relevance to autism

(2008) Sheryl S. Moy et al.   BEHAVIOURAL BRAIN RESEARCH

Familial deletion within NLGN4 associated with autism and Tourette syndrome

(2008) Amy Lawson-Yuen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A 12Mb deletion at 7q33–q35 associated with autism spectrum disorders and primary amenorrhea

(2008) Elena Rossi et al.   European Journal of Medical Genetics

Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2

(2008) J. Blundell et al.   GENES BRAIN AND BEHAVIOR

Social approach in genetically engineered mouse lines relevant to autism

(2008) S. S. Moy et al.   GENES BRAIN AND BEHAVIOR

S6K1 Phosphorylates and Regulates Fragile X Mental Retardation Protein (FMRP) with the Neuronal Protein Synthesis-dependent Mammalian Target of Rapamycin (mTOR) Signaling Cascade

(2008) Usha Narayanan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

(2008) A. Y. Hung et al.   JOURNAL OF NEUROSCIENCE

Copy-number variations associated with neuropsychiatric conditions

(2008) Edwin H. Cook Jr et al.   NATURE

Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis

(2008) Dan Ehninger et al.   NATURE MEDICINE

A Functional Genetic Link between Distinct Developmental Language Disorders

(2008) Sonja C. Vernes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Unusual Repertoire of Vocalizations in the BTBR T+tf/J Mouse Model of Autism

(2008) Maria Luisa Scattoni et al.   PLoS One

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

(2008) S. Jamain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals

(2008) Juhyun Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR