Mechanisms of Tactile Sensory Phenotypes in Autism: Current Understanding and Future Directions for Research

An amygdalar neural ensemble that encodes the unpleasantness of pain

(2019) Gregory Corder et al.   SCIENCE

Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion

(2019) Karuna S. Meda et al.   NEURON

Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models

(2019) Lauren L. Orefice et al.   CELL

Specialized cutaneous Schwann cells initiate pain sensation

(2019) Hind Abdo et al.   SCIENCE

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

(2018) Martin Häring et al.   NATURE NEUROSCIENCE

Comparative transcriptome profiling of the human and mouse dorsal root ganglia

(2018) Pradipta Ray et al.   PAIN

Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons

(2018) Kim Kridsada et al.   Cell Reports

Social touch and human development

(2018) Carissa J. Cascio et al.   Developmental Cognitive Neuroscience

Enhanced Nociception in Angelman Syndrome Model Mice

(2017) Eric S. McCoy et al.   JOURNAL OF NEUROSCIENCE

Tactile Defensiveness and Impaired Adaptation of Neuronal Activity in the Fmr1 Knock-Out Mouse Model of Autism

(2017) Cynthia X. He et al.   JOURNAL OF NEUROSCIENCE

Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1

(2017) Vaishnav Krishnan et al.   NATURE

Specialized Mechanosensory Nociceptors Mediating Rapid Responses to Hair Pull

(2017) Nima Ghitani et al.   NEURON

Neuronal cytoskeletal gene dysregulation and mechanical hypersensitivity in a rat model of Rett syndrome

(2017) Aritra Bhattacherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Somatosensory Neuron Typing with High-Coverage Single-Cell RNA Sequencing and Functional Analysis

(2017) Changlin Li et al.   Neuroscience Bulletin

Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs

(2016) Lauren L. Orefice et al.   CELL

Erratum: Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity

(2016) Chang-lin Li et al.   CELL RESEARCH

Roles of Cbln1 in Non-Motor Functions of Mice

(2016) Shintaro Otsuka et al.   JOURNAL OF NEUROSCIENCE

Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain

(2016) Lian Cui et al.   NEURON

SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons

(2016) Qingjian Han et al.   NEURON

Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking

(2015) Ling Bai et al.   CELL

Targeted Ablation, Silencing, and Activation Establish Glycinergic Dorsal Horn Neurons as Key Components of a Spinal Gate for Pain and Itch

(2015) Edmund Foster et al.   NEURON

Detecting autonomic response to pain in Rett syndrome

(2015) Heather M. O’Leary et al.   Developmental Neurorehabilitation

Methyl-CpG Binding Protein 2 (Mecp2) Regulates Sensory Function Through Sema5b and Robo2

(2015) Wan Y. Leong et al.   Frontiers in Cellular Neuroscience

Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders

(2015) Janine M LaSalle et al.   Epigenomics

Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury

(2015) Hugues Petitjean et al.   Cell Reports

Psychophysical Investigations into the Role of Low-Threshold C Fibres in Non-Painful Affective Processing and Pain Modulation

(2015) Sumaiya Shaikh et al.   PLoS One

Identification of Spinal Circuits Transmitting and Gating Mechanical Pain

(2014) Bo Duan et al.   CELL

Clinical and genomic evaluation of 201 patients with Phelan–McDermid syndrome

(2014) Sara M. Sarasua et al.   HUMAN GENETICS

Human C-Tactile Afferents Are Tuned to the Temperature of a Skin-Stroking Caress

(2014) R. Ackerley et al.   JOURNAL OF NEUROSCIENCE

Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1 −/y mice

(2014) Yu Zhang et al.   NATURE NEUROSCIENCE

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

(2014) Dmitry Usoskin et al.   NATURE NEUROSCIENCE

Tactile C fibers and their contributions to pleasant sensations and to tactile allodynia

(2014) Jaquette Liljencrantz et al.   Frontiers in Behavioral Neuroscience

Infant Calming Responses during Maternal Carrying in Humans and Mice

(2013) Gianluca Esposito et al.   CURRENT BIOLOGY

Genome-Wide Association Study of Autistic-Like Traits in a General Population Study of Young Adults

(2013) Rachel Maree Jones et al.   Frontiers in Human Neuroscience

Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo

(2013) Sophia Vrontou et al.   NATURE

How do children with autism spectrum disorders express pain? A comparison with developmentally delayed and typically developing children

(2013) Cécile Rattaz et al.   PAIN

Reevaluation of the role of parallel fiber synapses in delay eyeblink conditioning in mice using Cbln1 as a tool

(2013) Kyoichi Emi et al.   Frontiers in Neural Circuits

Autobiographical Accounts of Sensing in Asperger Syndrome and High-Functioning Autism

(2012) Marie Elwin et al.   ARCHIVES OF PSYCHIATRIC NURSING

Autistic traits are associated with diminished neural response to affective touch

(2012) Avery C. Voos et al.   Social Cognitive and Affective Neuroscience

The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

(2011) Lishi Li et al.   CELL

Brain mechanisms for processing affective touch

(2011) Ilanit Gordon et al.   HUMAN BRAIN MAPPING

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

(2011) Hsien-Sung Huang et al.   NATURE

LinkingMECP2and pain sensitivity: The example of Rett syndrome

(2010) Jenny Downs et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Clinical and genetic aspects of Angelman syndrome

(2010) Charles A Williams et al.   GENETICS IN MEDICINE

The Regularity of Sustained Firing Reveals Two Populations of Slowly Adapting Touch Receptors in Mouse Hairy Skin

(2010) Scott A. Wellnitz et al.   JOURNAL OF NEUROPHYSIOLOGY

Self-Injury among a Community Cohort of Young Children at Risk for Intellectual and Developmental Disabilities

(2010) William E. MacLean et al.   JOURNAL OF PEDIATRICS

Highly parallel SNP genotyping reveals high-resolution landscape of mono-allelic Ube3a expression associated with locus-wide antisense transcription

(2010) Koji Numata et al.   NUCLEIC ACIDS RESEARCH

A case of Rett syndrome with reduced pain sensitivity

(2010) Krishna M Devarakonda et al.   PEDIATRIC ANESTHESIA

Cbln1 Is a Ligand for an Orphan Glutamate Receptor  2, a Bidirectional Synapse Organizer

(2010) K. Matsuda et al.   SCIENCE

Coding of pleasant touch by unmyelinated afferents in humans

(2009) Line S Löken et al.   NATURE NEUROSCIENCE

Molecular Identification of Rapidly Adapting Mechanoreceptors and Their Developmental Dependence on Ret Signaling

(2009) Wenqin Luo et al.   NEURON

Quantitative assessment of pleasant touch

(2009) Greg K. Essick et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Visual Abilities and Sensory Differences in a Person with Autism

(2008) Temple Grandin   BIOLOGICAL PSYCHIATRY

The neurophysiology of unmyelinated tactile afferents

(2008) Håkan Olausson et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE