Structural Insights on Tiny Peptide Nucleic Acid (PNA) Analogues of miRNA-34a: An in silico and Experimental Integrated Approach

RNA-Based Therapeutics: From Antisense Oligonucleotides to miRNAs

(2020) Sarah Bajan et al.   Cells

Paper-based electrochemical peptide nucleic acid (PNA) biosensor for detection of miRNA-492: a pancreatic ductal adenocarcinoma biomarker

(2020) Maria Moccia et al.   BIOSENSORS & BIOELECTRONICS

MicroRNA replacement therapy in cancer

(2019) Homa Mollaei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Synthetic, Structural, and RNA Binding Studies on 2‐Aminopyridine‐Modified Triplex‐Forming Peptide Nucleic Acids

(2019) Venubabu Kotikam et al.   CHEMISTRY-A EUROPEAN JOURNAL

A combined experimental and computational study on peptide nucleic acid (PNA) analogues of tumor suppressive miRNA-34a

(2019) Valerio Piacenti et al.   BIOORGANIC CHEMISTRY

Advances in the discovery of microRNA-based anticancer therapeutics: latest tools and developments

(2019) Kenneth K.W. To et al.   Expert Opinion on Drug Discovery

A physiologically relevant 3D collagen-based scaffold–neuroblastoma cell system exhibits chemosensitivity similar to orthotopic xenograft models

(2018) C. Curtin et al.   Acta Biomaterialia

Treating cancer with microRNA replacement therapy: A literature review

(2018) Nayer Hosseinahli et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Improved Force Fields for Peptide Nucleic Acids with Optimized Backbone Torsion Parameters

(2018) Maciej Jasiński et al.   Journal of Chemical Theory and Computation

Anti-miRNA oligonucleotides: A comprehensive guide for design

(2018) Joana Filipa Lima et al.   RNA Biology

MiRNA Influences in Neuroblast Modulation: An Introspective Analysis

(2018) Vanessa Zammit et al.   Genes

Cobomarsen, an oligonucleotide inhibitor of miR-155, co-ordinately regulates multiple survival pathways to reduce cellular proliferation and survival in cutaneous T-cell lymphoma

(2018) Anita G. Seto et al.   BRITISH JOURNAL OF HAEMATOLOGY

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

(2018) Jacob O'Brien et al.   Frontiers in Endocrinology

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

Synthesis and DNA/RNA complementation studies of peptide nucleic acids containing 5-halouracils

(2017) Chun-dong Liu et al.   MedChemComm

The MYCN Protein in Health and Disease

(2017) María Victoria Ruiz-Pérez et al.   Genes

Focus on PNA Flexibility and RNA Binding using Molecular Dynamics and Metadynamics

(2017) Massimiliano Donato Verona et al.   Scientific Reports

RISC assembly: Coordination between small RNAs and Argonaute proteins

(2016) Hotaka Kobayashi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Argonaute 2-dependent Regulation of Gene Expression by Single-stranded miRNA Mimics

(2016) Masayuki Matsui et al.   MOLECULAR THERAPY

miRNA Deregulation in Cancer Cells and the Tumor Microenvironment

(2016) R. Rupaimoole et al.   Cancer Discovery

microRNA Therapeutics in Cancer — An Emerging Concept

(2016) Maitri Y. Shah et al.   EBioMedicine

In vivo delivery of miRNAs for cancer therapy: Challenges and strategies

(2015) Yunching Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Conformational studies of chiral d-Lys-PNA and achiral PNA system in binding with DNA or RNA through a molecular dynamics approach

(2015) Ida Autiero et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The Functions of MicroRNAs: mRNA Decay and Translational Repression

(2015) Hiro-oki Iwakawa et al.   TRENDS IN CELL BIOLOGY

Computational Biology in microRNA

(2015) Yue Li et al.   Wiley Interdisciplinary Reviews-RNA

miRNA-based therapies: strategies and delivery platforms for oligonucleotide and non-oligonucleotide agents

(2014) Volker Baumann et al.   Future Medicinal Chemistry

Activatable Cell Penetrating Peptide–Peptide Nucleic Acid Conjugate via Reduction of Azobenzene PEG Chains

(2014) Soo Hyeon Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quick-and-clean article figures with FigureJ

(2013) J. MUTTERER et al.   JOURNAL OF MICROSCOPY

Effects of Hypoxanthine Substitution in Peptide Nucleic Acids Targeting KRAS2 Oncogenic mRNA Molecules: Theory and Experiment

(2013) Jeffrey M. Sanders et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Synthesis and Biological Properties of Caffeic Acid-PNA Dimers Containing Guanine

(2013) Maria Gaglione et al.   MOLECULES

Molecular dynamics simulations of PNA–PNA and PNA–DNA duplexes by the use of new parameters implemented in the GROMACS package: a conformational and dynamics study

(2013) Ida Autiero et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

MicroRNAs and the cancer phenotype: profiling, signatures and clinical implications

(2013) Carlos Stahlhut et al.   Genome Medicine

Discovering the first microRNA-targeted drug

(2012) Morten Lindow et al.   JOURNAL OF CELL BIOLOGY

Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2

(2012) Yu Miyazaki et al.   NATURE MEDICINE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

γ sulphate PNA (PNA S): Highly Selective DNA Binding Molecule Showing Promising Antigene Activity

(2012) Concetta Avitabile et al.   PLoS One

MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion

(2012) L. Maegdefessel et al.   Science Translational Medicine

Clinical development of liposome based drugs: formulation, characterization, and therapeutic efficacy

(2011) Ming-Kung Yeh et al.   International Journal of Nanomedicine

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

Therapeutic targeting of miRNAs in neuroblastoma

(2010) Raymond L Stallings et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The structure of a γ-modified peptide nucleic acid duplex

(2010) Wei He et al.   Molecular BioSystems

Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes

(2010) Shintaro Iwasaki et al.   MOLECULAR CELL

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

(2010) Martin M. Fabani et al.   NUCLEIC ACIDS RESEARCH

Development of an efficient and low-cost protocol for the manual PNA synthesis by Fmoc chemistry

(2010) Concetta Avitabile et al.   TETRAHEDRON LETTERS

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Solution Structure of a Peptide Nucleic Acid Duplex from NMR Data: Features and Limitations

(2008) Wei He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The MC-Fold and MC-Sym pipeline infers RNA structure from sequence data

(2008) Marc Parisien et al.   NATURE

The MYCN oncogene is a direct target of miR-34a

(2008) J S Wei et al.   ONCOGENE