Therapeutic targeting of miRNAs in neuroblastoma

miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro

(2010) Hailan Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of miRNAs that are associated with tumor metastasis in Neuroblastoma

(2010) Jigang Guo et al.   CANCER BIOLOGY & THERAPY

Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q- Neuroblastoma

(2010) P. G. Buckley et al.   CLINICAL CANCER RESEARCH

Targeting MicroRNAs With Small Molecules: From Dream to Reality

(2010) S Zhang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2

(2010) Niamh H Foley et al.   Molecular Cancer

An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours

(2010) P Mestdagh et al.   ONCOGENE

MYCN-regulated microRNAs repress estrogen receptor-  (ESR1) expression and neuronal differentiation in human neuroblastoma

(2010) J. Loven et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic MicroRNA Strategies in Human Cancer

(2009) Chunsheng Li et al.   AAPS Journal

Transcribed-ultra conserved region expression is associated with outcome in high-risk neuroblastoma

(2009) Paola Scaruffi et al.   BMC CANCER

MicroRNA miR-29 Modulates Expression of Immunoinhibitory Molecule B7-H3: Potential Implications for Immune Based Therapy of Human Solid Tumors

(2009) H. Xu et al.   CANCER RESEARCH

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

Down-regulation of miR-17 family expression in response to retinoic acid induced neuronal differentiation

(2009) Natalie J. Beveridge et al.   CELLULAR SIGNALLING

microRNA Profiling Identifies Cancer-Specific and Prognostic Signatures in Pediatric Malignancies

(2009) J. S. Wei et al.   CLINICAL CANCER RESEARCH

MicroRNA Involvement in the Pathogenesis of Neuroblastoma: Potential for MicroRNA Mediated Therapeutics

(2009) R. Stallings   CURRENT PHARMACEUTICAL DESIGN

MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness

(2009) Cristina Evangelisti et al.   FASEB JOURNAL

The complexities of microRNA regulation: mirandering around the rules

(2009) Kimberly Breving et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

New therapeutic targets for the treatment of high-risk neuroblastoma

(2009) Lars M. Wagner et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Overall Genomic Pattern Is a Predictor of Outcome in Neuroblastoma

(2009) Isabelle Janoueix-Lerosey et al.   JOURNAL OF CLINICAL ONCOLOGY

Clusterin, a Haploinsufficient Tumor Suppressor Gene in Neuroblastomas

(2009) Olesya Chayka et al.   JNCI-Journal of the National Cancer Institute

Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

(2009) Joëlle Vermeulen et al.   LANCET ONCOLOGY

MicroRNA-125b Promotes Neuronal Differentiation in Human Cells by Repressing Multiple Targets

(2009) M. T. N. Le et al.   MOLECULAR AND CELLULAR BIOLOGY

Biological basis for restriction of microRNA targets to the 3′ untranslated region in mammalian mRNAs

(2009) Shuo Gu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Integrated genomic profiling identifies two distinct molecular subtypes with divergent outcome in neuroblastoma with loss of chromosome 11q

(2009) M Fischer et al.   ONCOGENE

MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors

(2009) P Mestdagh et al.   ONCOGENE

Widespread Dysregulation of MiRNAs by MYCN Amplification and Chromosomal Imbalances in Neuroblastoma: Association of miRNA Expression with Survival

(2009) Isabella Bray et al.   PLoS One

Global MYCN Transcription Factor Binding Analysis in Neuroblastoma Reveals Association with Distinct E-Box Motifs and Regions of DNA Hypermethylation

(2009) Derek M. Murphy et al.   PLoS One

MicroRNAs and cancer: what we know and what we still have to learn

(2009) George A Calin   Genome Medicine

New miRNAs cloned from neuroblastoma

(2008) Elena A Afanasyeva et al.   BMC GENOMICS

Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest

(2008) Fang Sun et al.   FEBS LETTERS

A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

(2008) K. A. Cole et al.   MOLECULAR CANCER RESEARCH

MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation

(2008) Ulf Andersson Ørom et al.   MOLECULAR CELL

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

The MYCN oncogene is a direct target of miR-34a

(2008) J S Wei et al.   ONCOGENE

Antagomir-17-5p Abolishes the Growth of Therapy-Resistant Neuroblastoma through p21 and BIM

(2008) Laura Fontana et al.   PLoS One

MicroRNA-373 induces expression of genes with complementary promoter sequences

(2008) R. F. Place et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-148 targets human DNMT3b protein coding region

(2008) A. M. Duursma et al.   RNA

MYCN regulates oncogenic MicroRNAs in neuroblastoma

(2007) Johannes H. Schulte et al.   INTERNATIONAL JOURNAL OF CANCER