Role of Neutrophils in Systemic Vasculitides

Enhanced formation of neutrophil extracellular traps in Kawasaki disease

(2020) Yusuke Yoshida et al.   PEDIATRIC RESEARCH

Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis

(2020) Carmelo Carmona-Rivera et al.   JCI Insight

ROS-producing immature neutrophils in giant cell arteritis are linked to vascular pathologies

(2020) Lihui Wang et al.   JCI Insight

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps

(2019) Sebastian Boeltz et al.   CELL DEATH AND DIFFERENTIATION

Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2

(2019) Carmelo Carmona-Rivera et al.   BLOOD

A case report dysregulated neutrophil extracellular traps in a patient with propylthiouracil-induced anti-neutrophil cytoplasmic antibody-associated vasculitis

(2019) Kanako Watanabe-Kusunoki et al.   MEDICINE

ANCA-Associated Vasculitis: Core Curriculum 2020

(2019) Duvuru Geetha et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Critical role of neutrophil extracellular traps (NETs) in patients with Behcet’s disease

(2019) Alexandre Le Joncour et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil extracellular trap formation is intrinsically distinct in ANCA ‐associated vasculitis and systemic lupus erythematosus

(2019) Laura S. van Dam et al.   Arthritis & Rheumatology

A Neutrophil Activation Biomarker Panel in Prognosis and Monitoring of Patients with Rheumatoid Arthritis

(2019) Mary Bach et al.   Arthritis & Rheumatology

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA

(2019) Yann Becker et al.   Frontiers in Immunology

An emerging role of neutrophils and NETosis in chronic inflammation and fibrosis in systemic lupus erythematosus (SLE) and ANCA-associated vasculitides (AAV): Implications for the pathogenesis and treatment

(2019) Eleni Frangou et al.   AUTOIMMUNITY REVIEWS

Neutrophil Extracellular Traps in Tissue and Periphery in Juvenile Dermatomyositis

(2019) Bhargavi Duvvuri et al.   Arthritis & Rheumatology

Clinical symptoms and associated vascular imaging findings in Takayasu’s arteritis compared to giant cell arteritis

(2019) Despina Michailidou et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil proteases degrade autoepitopes of NET‐associated proteins

(2019) C. M. Bont et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Low Density Granulocytes in ANCA Vasculitis Are Heterogenous and Hypo-Responsive to Anti-Myeloperoxidase Antibodies

(2019) Aisling Ui Mhaonaigh et al.   Frontiers in Immunology

Neutrophil extracellular traps identify patients at risk of increased disease activity and cardiovascular comorbidity in systemic lupus erythematosus

(2019) Stanley Moore et al.   JOURNAL OF RHEUMATOLOGY

Neutrophil Extracellular Traps in Autoimmunity and Allergy: Immune Complexes at Work

(2019) Vanessa Granger et al.   Frontiers in Immunology

Monosodium Urate Crystals Generate Nuclease-Resistant Neutrophil Extracellular Traps via a Distinct Molecular Pathway

(2018) Simon M. Chatfield et al.   JOURNAL OF IMMUNOLOGY

Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA

(2018) Tineke Kraaij et al.   KIDNEY INTERNATIONAL

Secukinumab for the maintenance of glucocorticoid-free remission in a patient with giant cell arteritis and psoriatic arthritis

(2018) Žiga Rotar et al.   RHEUMATOLOGY

Brief Report: Drugs Implicated in Systemic Autoimmunity Modulate Neutrophil Extracellular Trap Formation

(2018) Jorge A. Irizarry-Caro et al.   Arthritis & Rheumatology

Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides

(2018) Peter Lamprecht et al.   Frontiers in Immunology

TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA

(2017) Christian Lood et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Visual loss and other cranial ischaemic complications in giant cell arteritis

(2017) Alessandra Soriano et al.   Nature Reviews Rheumatology

Complement C5a-Induced Changes in Neutrophil Morphology During Inflammation

(2017) S. Denk et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Drug-induced large vessel vasculitis with carotid arterial ring sign

(2017) S Fukui et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio associated with disease activity in patients with Takayasu’s arteritis: a case-control study

(2017) Lili Pan et al.   BMJ Open

Neutrophil Extracellular Traps and Microcrystals

(2017) Balázs Rada   Journal of Immunology Research

Isolated abdominal aortitis following administration of granulocyte colony stimulating factor (G-CSF)

(2016) Edward B. Miller et al.   CLINICAL RHEUMATOLOGY

Calprotectin in rheumatic diseases

(2016) Francesca Ometto et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Giant Cell Arteritis which Developed after the Administration of Granulocyte-colony Stimulating Factor for Cyclic Neutropenia

(2016) Masataka Umeda et al.   INTERNAL MEDICINE

Neutrophil extracellular traps — the dark side of neutrophils

(2016) Ole E. Sørensen et al.   JOURNAL OF CLINICAL INVESTIGATION

Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus

(2016) Simone Caielli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetics and pathophysiology of granulomatosis with polyangiitis (GPA) and its main autoantigen proteinase 3

(2016) Manfred Relle et al.   MOLECULAR AND CELLULAR PROBES

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

Neutrophil extracellular traps as a potential source of autoantigen in cocaine-associated autoimmunity

(2016) Christian Lood et al.   RHEUMATOLOGY

Histone modification signature at myeloperoxidase and proteinase 3 in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis

(2016) Jiajin Yang et al.   Clinical Epigenetics

Association of Serum Calprotectin (S100A8/A9) Level With Disease Relapse in Proteinase 3-Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

(2016) Ruth J. Pepper et al.   Arthritis & Rheumatology

Platelet-Derived S100A8/A9 and Cardiovascular Disease in Systemic Lupus Erythematosus

(2016) Christian Lood et al.   Arthritis & Rheumatology

The Presence of Anti-Lactoferrin Antibodies in a Subgroup of Eosinophilic Granulomatosis with Polyangiitis Patients and Their Possible Contribution to Enhancement of Neutrophil Extracellular Trap Formation

(2016) Haruki Shida et al.   Frontiers in Immunology

Neutrophil Extracellular Traps in ANCA-Associated Vasculitis

(2016) Daniel Söderberg et al.   Frontiers in Immunology

GM-CSF as a target in inflammatory/autoimmune disease: current evidence and future therapeutic potential

(2015) John A Hamilton   Expert Review of Clinical Immunology

At the Bench: Neutrophil extracellular traps (NETs) highlight novel aspects of innate immune system involvement in autoimmune diseases

(2015) Peter C. Grayson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission

(2015) Daniel Söderberg et al.   RHEUMATOLOGY

Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

(2015) Peter C. Grayson et al.   Arthritis & Rheumatology

Autoantibodies in Systemic Vasculitis

(2015) Alexandre Wagner Silva de Souza   Frontiers in Immunology

IgA Enhances NETosis and Release of Neutrophil Extracellular Traps by Polymorphonuclear Cells via Fc  Receptor I

(2014) E. Aleyd et al.   JOURNAL OF IMMUNOLOGY

Enhanced Formation and Disordered Regulation of NETs in Myeloperoxidase-ANCA-Associated Microscopic Polyangiitis

(2014) D. Nakazawa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Neutrophils at work

(2014) William M Nauseef et al.   NATURE IMMUNOLOGY

Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease

(2014) J. Charles Jennette et al.   Nature Reviews Rheumatology

Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2

(2014) Qing Zhou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutant Adenosine Deaminase 2 in a Polyarteritis Nodosa Vasculopathy

(2014) Paulina Navon Elkan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutations in CECR1 associated with a neutrophil signature in peripheral blood

(2014) Alexandre Belot et al.   Pediatric Rheumatology

The immunopathology of ANCA-associated vasculitis

(2014) Eoin F. McKinney et al.   Seminars in Immunopathology

Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease

(2013) Konstantinos Kambas et al.   ANNALS OF THE RHEUMATIC DISEASES

The Multifaceted Functions of Neutrophils

(2013) Tanya N. Mayadas et al.   Annual Review of Pathology-Mechanisms of Disease

Investigational Analysis Reveals a Potential Role for Neutrophils in Giant-Cell Arteritis Disease Progression

(2013) Suchita Nadkarni et al.   CIRCULATION RESEARCH

Trojan horses

(2013) William F. Pendergraft et al.   CURRENT OPINION IN RHEUMATOLOGY

Interleukin-1 blockade in refractory giant cell arteritis

(2013) Kim-Heang Ly et al.   JOINT BONE SPINE

C5a Receptor (CD88) Blockade Protects against MPO-ANCA GN

(2013) H. Xiao et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Leukocyte and serum S100A8/S100A9 expression reflects disease activity in ANCA-associated vasculitis and glomerulonephritis

(2013) Ruth J. Pepper et al.   KIDNEY INTERNATIONAL

The influence of cathelicidin LL37 in human anti-neutrophils cytoplasmic antibody (ANCA)-associated vasculitis

(2013) Ying Zhang et al.   ARTHRITIS RESEARCH & THERAPY

Abnormal conformation and impaired degradation of propylthiouracil-induced neutrophil extracellular traps: Implications of disordered neutrophil extracellular traps in a rat model of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculiti

(2012) Daigo Nakazawa et al.   ARTHRITIS AND RHEUMATISM

2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

(2012) J. C. Jennette et al.   ARTHRITIS AND RHEUMATISM

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): Clinical characteristics and long-term followup of the 383 patients enrolled in the French Vasculitis Study Group cohort

(2012) Cloé Comarmond et al.   ARTHRITIS AND RHEUMATISM

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

(2012) S. Sangaletti et al.   BLOOD

How anti-neutrophil cytoplasmic autoantibodies activate neutrophils

(2012) R. Kettritz   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Rheumatic manifestations of cocaine use

(2012) Jonathan Graf   CURRENT OPINION IN RHEUMATOLOGY

Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease

(2012) J. Leffler et al.   JOURNAL OF IMMUNOLOGY

Endothelium-Neutrophil Interactions in ANCA-Associated Diseases

(2012) L. Halbwachs et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody–associated vasculitis

(2012) Shen-Ju Gou et al.   KIDNEY INTERNATIONAL

Cytokines Induced Neutrophil Extracellular Traps Formation: Implication for the Inflammatory Disease Condition

(2012) Ravi S. Keshari et al.   PLoS One

C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis

(2012) Jun Yuan et al.   ARTHRITIS RESEARCH & THERAPY

Pathogenesis of Takayasu's arteritis: A 2011 update

(2011) Laurent Arnaud et al.   AUTOIMMUNITY REVIEWS

Nomenclature and classification of vasculitis: lessons learned from granulomatosis with polyangiitis (Wegener's granulomatosis)

(2011) J. C. Jennette   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

(2010) Quinten Remijsen et al.   CELL RESEARCH

Th17 and Th1 T-Cell Responses in Giant Cell Arteritis

(2010) Jiusheng Deng et al.   CIRCULATION

Enhanced expression of the tumour necrosis factor/cachectin gene in peripheral blood mononuclear cells from patients with systemic vasculitis

(2010) Y. DEGUCHI et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo

(2010) E. CSERNOK et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pathogenesis and management of Kawasaki disease

(2010) Anne H Rowley et al.   Expert Review of Anti-Infective Therapy

Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death

(2010) Anurag Kumar Gupta et al.   FEBS LETTERS

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Takayasu Arteritis and Giant Cell Arteritis

(2009) Kathleen Maksimowicz-McKinnon et al.   MEDICINE

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

C5a Receptor Mediates Neutrophil Activation and ANCA-Induced Glomerulonephritis

(2008) A. Schreiber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY