Aging induces B cell defects and decreased antibody responses to influenza infection and vaccination
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Aging induces B cell defects and decreased antibody responses to influenza infection and vaccination
Authors
Keywords
-
Journal
Immunity & Ageing
Volume 17, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-11-19
DOI
10.1186/s12979-020-00210-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Seasonal Variability and Shared Molecular Signatures of Inactivated Influenza Vaccination in Young and Older Adults
- (2020) Stefan Avey et al. JOURNAL OF IMMUNOLOGY
- Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
- (2020) Nanshan Chen et al. LANCET
- The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans
- (2020) John L. Johnson et al. IMMUNITY
- Rates of Co-infection Between SARS-CoV-2 and Other Respiratory Pathogens
- (2020) David Kim et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The clinical characteristics of pneumonia patients coinfected with 2019 novel coronavirus and influenza virus in Wuhan, China
- (2020) Qiang Ding et al. JOURNAL OF MEDICAL VIROLOGY
- The immune response to influenza in older humans: beyond immune senescence
- (2020) Janet E. McElhaney et al. Immunity & Ageing
- Use of seasonal influenza and pneumococcal polysaccharide vaccines in older adults to reduce COVID-19 mortality
- (2020) Deus Thindwa et al. VACCINE
- Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals
- (2019) Carole Henry et al. Cell Host & Microbe
- Metabolic requirements of human pro-inflammatory B cells in aging and obesity
- (2019) Daniela Frasca et al. PLoS One
- Host factors impact vaccine efficacy: implications for seasonal and universal influenza vaccine programs
- (2019) Santosh Dhakal et al. JOURNAL OF VIROLOGY
- Microarray Gene Expression Dataset Re-analysis Reveals Variability in Influenza Infection and Vaccination
- (2019) Lavida R. K. Rogers et al. Frontiers in Immunology
- Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low PAX5
- (2018) Allison J. Nipper et al. CLINICAL IMMUNOLOGY
- Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains
- (2018) Chia-Hsin Ju et al. CLINICAL IMMUNOLOGY
- Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells
- (2018) Noémie Gensous et al. EXPERIMENTAL GERONTOLOGY
- Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation
- (2018) Difeng Fang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Estimates of global seasonal influenza-associated respiratory mortality: a modelling study
- (2018) A Danielle Iuliano et al. LANCET
- H3N2 influenza viruses in humans: Viral mechanisms, evolution, and evaluation
- (2018) James D. Allen et al. Human Vaccines & Immunotherapeutics
- Age-Related Changes in the Natural Killer Cell Response to Seasonal Influenza Vaccination Are Not Influenced by a Synbiotic: a Randomised Controlled Trial
- (2018) Agnieszka Przemska-Kosicka et al. Frontiers in Immunology
- Human peripheral late/exhausted memory B cells express a senescent-associated secretory phenotype and preferentially utilize metabolic signaling pathways
- (2017) Daniela Frasca et al. EXPERIMENTAL GERONTOLOGY
- Age-Associated B Cells Express a Diverse Repertoire of VHand Vκ Genes with Somatic Hypermutation
- (2017) Lisa M. Russell Knode et al. JOURNAL OF IMMUNOLOGY
- Inflammation, metaflammation and immunometabolic disorders
- (2017) Gökhan S. Hotamisligil NATURE
- Inflammaging and ‘Garb-aging’
- (2017) Claudio Franceschi et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Do antibody responses to the influenza vaccine persist year-round in the elderly? A systematic review and meta-analysis
- (2017) Barnaby Young et al. VACCINE
- Factors affecting immune responses to the influenza vaccine
- (2017) Maria R. Castrucci Human Vaccines & Immunotherapeutics
- Beyond autophagy: New roles for ULK1 in immune signaling and interferon responses
- (2016) Diana Saleiro et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells
- (2016) Martin S. Naradikian et al. JOURNAL OF IMMUNOLOGY
- Age-Associated B Cells with Proinflammatory Characteristics Are Expanded in a Proportion of Multiple Sclerosis Patients
- (2016) Nele Claes et al. JOURNAL OF IMMUNOLOGY
- Hepatitis C viraemia reversibly maintains subset of antigen-specific T-bet+ tissue-like memory B cells
- (2016) L.-Y. Chang et al. JOURNAL OF VIRAL HEPATITIS
- Regulated localization of an AID complex with E2A, PAX5 and IRF4 at the Igh locus
- (2016) Jannek Hauser et al. MOLECULAR IMMUNOLOGY
- Obesity decreases B cell responses in young and elderly individuals
- (2016) Daniela Frasca et al. Obesity
- System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination
- (2016) Michael T. Zimmermann et al. PLoS One
- The confounded effects of age and exposure history in response to influenza vaccination
- (2016) Ana Mosterín Höpping et al. VACCINE
- The generation of memory B cells is maintained, but the antibody response is not, in the elderly after repeated influenza immunizations
- (2016) Daniela Frasca et al. VACCINE
- Immunosenescence-Related Transcriptomic and Immunologic Changes in Older Individuals Following Influenza Vaccination
- (2016) Richard B. Kennedy et al. Frontiers in Immunology
- Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination
- (2015) Juilee Thakar et al. Aging-US
- Inflammaging decreases adaptive and innate immune responses in mice and humans
- (2015) Daniela Frasca et al. BIOGERONTOLOGY
- Influenza virus-induced lung injury: pathogenesis and implications for treatment
- (2015) Susanne Herold et al. EUROPEAN RESPIRATORY JOURNAL
- Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures
- (2015) Helder I. Nakaya et al. IMMUNITY
- MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals
- (2015) Daniela Frasca et al. JOURNAL OF IMMUNOLOGY
- Telomere Length as an Indicator of the Robustness of B- and T-Cell Response to Influenza in Older Adults
- (2015) Kevin Najarro et al. JOURNAL OF INFECTIOUS DISEASES
- High Preexisting Serological Antibody Levels Correlate with Diversification of the Influenza Vaccine Response
- (2015) Sarah F. Andrews et al. JOURNAL OF VIROLOGY
- Ageing of the B-cell repertoire
- (2015) Victoria Martin et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response
- (2015) Diana G. Adlowitz et al. PLoS One
- Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses
- (2014) John S. Tsang et al. CELL
- High TNF-α levels in resting B cells negatively correlate with their response
- (2014) Daniela Frasca et al. EXPERIMENTAL GERONTOLOGY
- Memory B cells form in aged mice despite impaired affinity maturation and germinal center kinetics
- (2014) Radhika Goenka et al. EXPERIMENTAL GERONTOLOGY
- Ageing and respiratory infections: The airway of ageing
- (2014) Kamran Haq et al. IMMUNOLOGY LETTERS
- Aging Down-Regulates the Transcription Factor E2A, Activation-Induced Cytidine Deaminase, and Ig Class Switch in Human B Cells
- (2014) D. Frasca et al. JOURNAL OF IMMUNOLOGY
- Prolonged Proinflammatory Cytokine Production in Monocytes Modulated by Interleukin 10 After Influenza Vaccination in Older Adults
- (2014) Subhasis Mohanty et al. JOURNAL OF INFECTIOUS DISEASES
- Designing Vaccines for the Twenty-First Century Society
- (2014) Oretta Finco et al. Frontiers in Immunology
- Effects of Aging, Cytomegalovirus Infection, and EBV Infection on Human B Cell Repertoires
- (2013) C. Wang et al. JOURNAL OF IMMUNOLOGY
- Frailty in elderly people
- (2013) Andrew Clegg et al. LANCET
- Adipose tissue, diet and aging
- (2013) Mauro Zamboni et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Apoptosis and other immune biomarkers predict influenza vaccine responsiveness
- (2013) D. Furman et al. Molecular Systems Biology
- Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination
- (2013) D. Furman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lineage Structure of the Human Antibody Repertoire in Response to Influenza Vaccination
- (2013) N. Jiang et al. Science Translational Medicine
- Young and elderly patients with type 2 diabetes have optimal B cell responses to the seasonal influenza vaccine
- (2013) Daniela Frasca et al. VACCINE
- Effects of age on H1N1-specific serum IgG1 and IgG3 levels evaluated during the 2011–2012 influenza vaccine season
- (2013) Daniela Frasca et al. Immunity & Ageing
- Unique biomarkers for B-cell function predict the serum response to pandemic H1N1 influenza vaccine
- (2012) D. Frasca et al. INTERNATIONAL IMMUNOLOGY
- Chronic Exposure to Plasmodium falciparum Is Associated with Phenotypic Evidence of B and T Cell Exhaustion
- (2012) J. Illingworth et al. JOURNAL OF IMMUNOLOGY
- Influenza Virus H1N1pdm09 Infections in the Young and Old: Evidence of Greater Antibody Diversity and Affinity for the Hemagglutinin Globular Head Domain (HA1 Domain) in the Elderly than in Young Adults and Children
- (2012) N. Verma et al. JOURNAL OF VIROLOGY
- The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines
- (2012) Janet E. McElhaney et al. VACCINE
- Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination
- (2012) Evelyna Derhovanessian et al. VACCINE
- AID Activity in B Cells Strongly Correlates with Polyclonal Antibody Affinity Maturation in-vivo Following Pandemic 2009-H1N1 Vaccination in Humans
- (2012) Surender Khurana et al. PLoS Pathogens
- A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
- (2011) Y. Hao et al. BLOOD
- Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity
- (2011) A. V. Rubtsov et al. BLOOD
- Fatty Kidney, Hypertension, and Chronic Kidney Disease
- (2011) Meredith C. Foster et al. HYPERTENSION
- Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies
- (2011) Sanae Sasaki et al. JOURNAL OF CLINICAL INVESTIGATION
- Natural killer cell function is altered during the primary response of aged mice to influenza infection
- (2011) Eleni Beli et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Fat tissue, aging, and cellular senescence
- (2010) Tamara Tchkonia et al. AGING CELL
- B cell repertoire and ageing
- (2010) Deborah K Dunn-Walters et al. CURRENT OPINION IN IMMUNOLOGY
- A call to cellular & humoral arms: Enlisting cognate T cell help to develop broad-spectrum vaccines against influenza A
- (2010) Julie A. McMurry et al. Human vaccines & immunotherapeutics
- Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine
- (2010) Davide Corti et al. JOURNAL OF CLINICAL INVESTIGATION
- Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response
- (2010) Alexander Panda et al. JOURNAL OF IMMUNOLOGY
- Cross-Neutralization of 1918 and 2009 Influenza Viruses: Role of Glycans in Viral Evolution and Vaccine Design
- (2010) C.-J. Wei et al. Science Translational Medicine
- Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans
- (2010) Daniela Frasca et al. VACCINE
- Immunosenescence: what does it mean to health outcomes in older adults?
- (2009) Janet E McElhaney et al. CURRENT OPINION IN IMMUNOLOGY
- CXCL16 in HIV infection - a link between inflammation and viral replication
- (2009) L. Landrø et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Factors Associated With Death or Hospitalization Due to Pandemic 2009 Influenza A(H1N1) Infection in California
- (2009) Janice K. Louie JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Modulation of T Lymphocyte Replicative Senescence via TNF- Inhibition: Role of Caspase-3
- (2009) S. T. Parish et al. JOURNAL OF IMMUNOLOGY
- A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people
- (2009) Giuseppina Colonna-Romano et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults
- (2009) Janet E. McElhaney et al. VACCINE
- Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection
- (2008) Arnaud Didierlaurent et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
- (2008) Susan Moir et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
- (2008) Jens Wrammert et al. NATURE
- Epicardial Adipose Tissue Extent: Relationship With Age, Body Fat Distribution, and Coronaropathy
- (2008) Alina Silaghi et al. Obesity
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search