Influenza Virus H1N1pdm09 Infections in the Young and Old: Evidence of Greater Antibody Diversity and Affinity for the Hemagglutinin Globular Head Domain (HA1 Domain) in the Elderly than in Young Adults and Children

Aging Down-Regulates the Transcription Factor E2A, Activation-Induced Cytidine Deaminase, and Ig Class Switch in Human B Cells

(2014) D. Frasca et al.   JOURNAL OF IMMUNOLOGY

Revisiting the 1976 "Swine Flu" Vaccine Clinical Trials: Cross-reactive Hemagglutinin and Neuraminidase Antibodies and Their Role in Protection Against the 2009 H1N1 Pandemic Virus in Mice

(2011) H. Xie et al.   CLINICAL INFECTIOUS DISEASES

Serological study of the 2009 pandemic due to influenza A H1N1 in the metropolitan French population

(2011) J. Delangue et al.   CLINICAL MICROBIOLOGY AND INFECTION

Quantity, not quality, of antibody response decreased in the elderly

(2011) Bonnie B. Blomberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies

(2011) Sanae Sasaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Serological responses following influenza A H1N1 2009 infection in adults

(2011) Sophia Tan et al.   JOURNAL OF INFECTION

Complications and Outcomes of Pandemic 2009 Influenza A (H1N1) Virus Infection in Hospitalized Adults: How Do They Differ From Those in Seasonal Influenza?

(2011) N. Lee et al.   JOURNAL OF INFECTIOUS DISEASES

Immune Response Following H1N1pdm09 Vaccination: Differences in Antibody Repertoire and Avidity in Young Adults and Elderly Populations Stratified by Age and Gender

(2011) Surender Khurana et al.   JOURNAL OF INFECTIOUS DISEASES

A Broadly Neutralizing Human Monoclonal Antibody That Recognizes a Conserved, Novel Epitope on the Globular Head of the Influenza H1N1 Virus Hemagglutinin

(2011) J. C. Krause et al.   JOURNAL OF VIROLOGY

Elicitation of Anti-1918 Influenza Virus Immunity Early in Life Prevents Morbidity and Lower Levels of Lung Infection by 2009 Pandemic H1N1 Influenza Virus in Aged Mice

(2011) B. M. Giles et al.   JOURNAL OF VIROLOGY

MF59 Adjuvant Enhances Diversity and Affinity of Antibody-Mediated Immune Response to Pandemic Influenza Vaccines

(2011) S. Khurana et al.   Science Translational Medicine

Targeting B cell responses in universal influenza vaccine design

(2011) Kaval Kaur et al.   TRENDS IN IMMUNOLOGY

Recipients of Vaccine against the 1976 “Swine Flu” Have Enhanced Neutralization Responses to the 2009 Novel H1N1 Influenza Virus

(2010) Jonathan A. McCullers et al.   CLINICAL INFECTIOUS DISEASES

Epidemiology of 2009 Pandemic Influenza A (H1N1) in the United States

(2010) Michael A. Jhung et al.   CLINICAL INFECTIOUS DISEASES

Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine

(2010) Davide Corti et al.   JOURNAL OF CLINICAL INVESTIGATION

Immuno-epidemiologic Correlates of Pandemic H1N1 Surveillance Observations: Higher Antibody and Lower Cell-Mediated Immune Responses with Advanced Age

(2010) D. M. Skowronski et al.   JOURNAL OF INFECTIOUS DISEASES

Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes

(2010) Ana Clara Monsalvo et al.   NATURE MEDICINE

Properly Folded Bacterially Expressed H1N1 Hemagglutinin Globular Head and Ectodomain Vaccines Protect Ferrets against H1N1 Pandemic Influenza Virus

(2010) Surender Khurana et al.   PLoS One

Seroprevalence Following the Second Wave of Pandemic 2009 H1N1 Influenza in Pittsburgh, PA, USA

(2010) Shanta M. Zimmer et al.   PLoS One

Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

(2010) R. Xu et al.   SCIENCE

Vaccines with MF59 Adjuvant Expand the Antibody Repertoire to Target Protective Sites of Pandemic Avian H5N1 Influenza Virus

(2010) S. Khurana et al.   Science Translational Medicine

Inactivated trivalent seasonal influenza vaccine induces limited cross-reactive neutralizing antibody responses against 2009 pandemic and 1934 PR8 H1N1 strains

(2010) Vernon J. Lee et al.   VACCINE

Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans

(2010) Daniela Frasca et al.   VACCINE

Modeling host responses in ferrets during A/California/07/2009 influenza infection

(2010) Thomas Rowe et al.   VIROLOGY

Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Cross-Reactive Antibody Responses to the 2009 Pandemic H1N1 Influenza Virus

(2009) Kathy Hancock et al.   NEW ENGLAND JOURNAL OF MEDICINE

Severe Respiratory Disease Concurrent with the Circulation of H1N1 Influenza

(2009) Gerardo Chowell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antigenic Fingerprinting of H5N1 Avian Influenza Using Convalescent Sera and Monoclonal Antibodies Reveals Potential Vaccine and Diagnostic Targets

(2009) Surender Khurana et al.   PLOS MEDICINE

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

(2008) Xiaocong Yu et al.   NATURE