Epigenetic regulation of inflammation in periodontitis: cellular mechanisms and therapeutic potential
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Title
Epigenetic regulation of inflammation in periodontitis: cellular mechanisms and therapeutic potential
Authors
Keywords
-
Journal
Clinical Epigenetics
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-12-01
DOI
10.1186/s13148-020-00982-7
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Note: Only part of the references are listed.- DNA methylation profile of genes related to immune response in generalized periodontitis
- (2020) Andrea Mara Azevedo et al. JOURNAL OF PERIODONTAL RESEARCH
- Epigenetic modifier trichostatin A enhanced osteogenic differentiation of mesenchymal stem cells by inhibiting NF‐κB (p65) DNA binding and promoted periodontal repair in rats
- (2020) Qiong Li et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Expression of MicroRNAs in Periodontal and Peri-Implant Diseases: A Systematic Review and Meta-Analysis
- (2020) Farah Asa’ad et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Histone Methylation: Achilles Heel and Powerful Mediator of Periodontal Homeostasis
- (2020) M. Francis et al. JOURNAL OF DENTAL RESEARCH
- SETD1 and NF-κB Regulate Periodontal Inflammation through H3K4 Trimethylation
- (2020) M. Francis et al. JOURNAL OF DENTAL RESEARCH
- Association between periodontal pathogens and systemic disease
- (2019) Fiona Q. Bui et al. Biomedical Journal
- Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors
- (2019) Stephen S. Dominy et al. Science Advances
- Comparison of Subgingival and Buccal Mucosa Microbiome in Chronic and Aggressive Periodontitis: A Pilot Study
- (2019) Yiping Wei et al. Frontiers in Cellular and Infection Microbiology
- Epigenetic findings in periodontitis in UK twins: a cross-sectional study
- (2019) Yuko Kurushima et al. Clinical Epigenetics
- Gene activation precedes DNA demethylation in response to infection in human dendritic cells
- (2019) Alain Pacis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteomic Analysis of Azacitidine-Induced Degradation Profiles Identifies Multiple Chromatin and Epigenetic Regulators Including Uhrf1 and Dnmt1 as Sensitive to Azacitidine
- (2019) Emily H Bowler et al. JOURNAL OF PROTEOME RESEARCH
- TET1 Knockdown Inhibits Porphyromonas gingivalis LPS/IFN-γ-Induced M1 Macrophage Polarization through the NF-κB Pathway in THP-1 Cells
- (2019) Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigenetic and inflammatory events in experimental periodontitis following systemic microbial challenge
- (2019) Daniela B. Palioto et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Smoking and DNA methylation: Correlation of methylation with smoking behavior and association with diseases and fetus development following prenatal exposure
- (2019) Domniki Fragou et al. FOOD AND CHEMICAL TOXICOLOGY
- BET Bromodomain Inhibitors Suppress Inflammatory Activation of Gingival Fibroblasts and Epithelial Cells From Periodontitis Patients
- (2019) Anna Maksylewicz et al. Frontiers in Immunology
- Protein Interactions at Oxidized 5-Methylcytosine Bases
- (2019) Gerd P. Pfeifer et al. JOURNAL OF MOLECULAR BIOLOGY
- Histone Methylation Mechanisms Modulate the Inflammatory Response of Periodontal Ligament Progenitors
- (2019) Marybeth Francis et al. STEM CELLS AND DEVELOPMENT
- Sensitivity of transcription factors to DNA methylation
- (2019) Éléa Héberlé et al. Essays in Biochemistry
- Role of epigenetics in alveolar bone resorption and regeneration around periodontal and peri‐implant tissues
- (2019) Farah Asa'ad et al. EUROPEAN JOURNAL OF ORAL SCIENCES
- HDAC3 Regulates Gingival Fibroblast Inflammatory Responses in Periodontitis
- (2019) K.B. Lagosz et al. JOURNAL OF DENTAL RESEARCH
- Differential DNA methylation correlates with response to methotrexate in rheumatoid arthritis
- (2019) Nisha Nair et al. RHEUMATOLOGY
- Interleukin 1β and Prostaglandin E2 affect expression of DNA methylating and demethylating enzymes in human gingival fibroblasts
- (2019) Sara Seutter et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- BET bromodomains’ functions in bone-related pathologies
- (2019) Camille Jacques et al. Epigenomics
- An epigenetic biomarker of aging for lifespan and healthspan
- (2018) Morgan E. Levine et al. Aging-US
- Jumonji domain-containing protein 3 regulates the early inflammatory response epigenetically in human periodontal ligament cells
- (2018) Puyu Wang et al. ARCHIVES OF ORAL BIOLOGY
- DNA methylcytosine dioxygenase ten-eleven translocation 2 enhances lipopolysaccharide-induced cytokine expression in human dental pulp cells by regulating MyD88 hydroxymethylation
- (2018) Xinxuan Wang et al. CELL AND TISSUE RESEARCH
- Treponema denticola increases MMP-2 expression and activation in the periodontium via reversible DNA and histone modifications
- (2018) Islam M. Ateia et al. CELLULAR MICROBIOLOGY
- Staging and grading of periodontitis: Framework and proposal of a new classification and case definition
- (2018) Maurizio S. Tonetti et al. JOURNAL OF PERIODONTOLOGY
- Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
- (2018) Sébastien Lucas et al. Nature Communications
- Gene expression profiling of periodontitis-affected gingival tissue by spatial transcriptomics
- (2018) Anna Lundmark et al. Scientific Reports
- Multi-species oral biofilm promotes reconstructed human gingiva epithelial barrier function
- (2018) Lin Shang et al. Scientific Reports
- Butyrate Stimulates Histone H3 Acetylation, 8-Isoprostane Production, RANKL Expression, and Regulated Osteoprotegerin Expression/Secretion in MG-63 Osteoblastic Cells
- (2018) Mei-Chi Chang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Identification of genetic risk factors of aggressive periodontitis using genomewide association studies in association with those of chronic periodontitis
- (2018) Risa Masumoto et al. JOURNAL OF PERIODONTAL RESEARCH
- The oral microbiota: dynamic communities and host interactions
- (2018) Richard J. Lamont et al. NATURE REVIEWS MICROBIOLOGY
- Evaluation of DNA methylation of inflammatory genes following treatment of chronic periodontitis: A pilot case-control study
- (2017) Farah Asa'ad et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Direct Gingival Fibroblast/Osteoblast Transdifferentiation via Epigenetics
- (2017) Y. Cho et al. JOURNAL OF DENTAL RESEARCH
- The case for periodontitis in the pathogenesis of rheumatoid arthritis
- (2017) Jan Potempa et al. Nature Reviews Rheumatology
- BET Proteins as Targets for Anticancer Treatment
- (2017) Anastasios Stathis et al. Cancer Discovery
- Genes Critical for Developing Periodontitis: Lessons from Mouse Models
- (2017) Teun J. de Vries et al. Frontiers in Immunology
- New Insights into 5hmC DNA Modification: Generation, Distribution and Function
- (2017) Dong-Qiao Shi et al. Frontiers in Genetics
- Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes
- (2016) Chiara Angiolilli et al. ANNALS OF THE RHEUMATIC DISEASES
- IFI44Lpromoter methylation as a blood biomarker for systemic lupus erythematosus
- (2016) Ming Zhao et al. ANNALS OF THE RHEUMATIC DISEASES
- Increased expression of interleukin-6 (IL-6) gene transcript in relation to IL-6 promoter hypomethylation in gingival tissue from patients with chronic periodontitis
- (2016) Tetsuo Kobayashi et al. ARCHIVES OF ORAL BIOLOGY
- The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies
- (2016) Madeleine Duvic et al. CANCER TREATMENT REVIEWS
- A Lasting Impression: Epigenetic Memory of Bacterial Infections?
- (2016) Jorge M. Pereira et al. Cell Host & Microbe
- Expression of TET2 enzyme indicates enhanced epigenetic modification of cells in periodontitis
- (2016) Lena Larsson et al. EUROPEAN JOURNAL OF ORAL SCIENCES
- Epigenetic characteristics in inflammatory candidate genes in aggressive periodontitis
- (2016) Susanne Schulz et al. HUMAN IMMUNOLOGY
- Gingival crevicular fluid levels of cytokines/chemokines in chronic periodontitis: a meta-analysis
- (2016) Amanda F. Stadler et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Alcohol consumption and risk of periodontitis: a meta-analysis
- (2016) Jiantao Wang et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Molecular mechanisms of innate memory and tolerance to LPS
- (2016) John J. Seeley et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Epigenetic drug discovery: breaking through the immune barrier
- (2016) David F. Tough et al. NATURE REVIEWS DRUG DISCOVERY
- Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation
- (2016) Aline C. Planello et al. Oncotarget
- Epigenetics in autoimmune diseases: Pathogenesis and prospects for therapy
- (2015) Zimu Zhang et al. AUTOIMMUNITY REVIEWS
- The interplay of histone modifications - writers that read
- (2015) T. Zhang et al. EMBO REPORTS
- Two distinct modes for propagation of histone PTMs across the cell cycle
- (2015) Constance Alabert et al. GENES & DEVELOPMENT
- What Do You Mean, “Epigenetic”?
- (2015) Carrie Deans et al. GENETICS
- Inhibition of Histone Deacetylases Enhances the Osteogenic Differentiation of Human Periodontal Ligament Cells
- (2015) Nam Cong-Nhat Huynh et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Epigenetic Modifications of Histones in Periodontal Disease
- (2015) M.D. Martins et al. JOURNAL OF DENTAL RESEARCH
- Class I and II histone deacetylase expression in human chronic periodontitis gingival tissue
- (2015) M. D. Cantley et al. JOURNAL OF PERIODONTAL RESEARCH
- DNA hypermethylation of extracellular matrix-related genes in human periodontal fibroblasts induced by stimulation for a prolonged period with lipopolysaccharide derived fromPorphyromonas gingivalis
- (2015) R. Takai et al. JOURNAL OF PERIODONTAL RESEARCH
- Tumor necrosis factor-alpha gene promoter methylation in Japanese adults with chronic periodontitis and rheumatoid arthritis
- (2015) A. Kojima et al. JOURNAL OF PERIODONTAL RESEARCH
- Structural insight into substrate preference for TET-mediated oxidation
- (2015) Lulu Hu et al. NATURE
- Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6
- (2015) Qian Zhang et al. NATURE
- DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies
- (2015) Xu Gao et al. Clinical Epigenetics
- What Do You Mean, “Epigenetic”?
- (2015) Carrie Deans et al. GENETICS
- DNA methylation differentially regulates cytokine secretion in gingival epithelia in response to bacterial challenges
- (2015) Jeanie L. Drury et al. Pathogens and Disease
- Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression
- (2014) Chiara Angiolilli et al. ANNALS OF THE RHEUMATIC DISEASES
- The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts
- (2014) Kerstin Klein et al. ANNALS OF THE RHEUMATIC DISEASES
- DNA methylation levels of SOCS1 and LINE-1 in oral epithelial cells from aggressive periodontitis patients
- (2014) N.B. Baptista et al. ARCHIVES OF ORAL BIOLOGY
- Interpreting the language of histone and DNA modifications
- (2014) Scott B. Rothbart et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Grasping nettles: cellular heterogeneity and other confounders in epigenome-wide association studies
- (2014) L. Liang et al. HUMAN MOLECULAR GENETICS
- BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction
- (2014) S. Meng et al. JOURNAL OF DENTAL RESEARCH
- TLR2 Promoter Hypermethylation Creates Innate Immune Dysbiosis
- (2014) M. Benakanakere et al. JOURNAL OF DENTAL RESEARCH
- Short-Chain Fatty Acids from Periodontal Pathogens Suppress Histone Deacetylases, EZH2, and SUV39H1 To Promote Kaposi's Sarcoma-Associated Herpesvirus Replication
- (2014) X. Yu et al. JOURNAL OF VIROLOGY
- Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
- (2014) S. Saeed et al. SCIENCE
- Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition
- (2014) R. Marmorstein et al. Cold Spring Harbor Perspectives in Biology
- High-throughput DNA analysis shows the importance of methylation in the control of immune inflammatory gene transcription in chronic periodontitis
- (2014) Ana De Souza et al. Clinical Epigenetics
- Gingival fibroblasts from periodontitis patients exhibit inflammatory characteristics in vitro
- (2013) Keum Jin Baek et al. ARCHIVES OF ORAL BIOLOGY
- Challenges for the application of DNA methylation biomarkers in molecular diagnostic testing for cancer
- (2013) Surbhi Jain et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Hypermethylation and low transcription of TLR2 gene in chronic periodontitis
- (2013) Simone Angélica de Faria Amormino et al. HUMAN IMMUNOLOGY
- BET bromodomain inhibition suppresses TH17-mediated pathology
- (2013) Deanna A. Mele et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulation of NO Synthesis, Local Inflammation, and Innate Immunity to Pathogens by BET Family Proteins
- (2013) S. Wienerroither et al. MOLECULAR AND CELLULAR BIOLOGY
- The ascent of acetylation in the epigenetics of rheumatoid arthritis
- (2013) Aleksander M. Grabiec et al. Nature Reviews Rheumatology
- Analysis of histone deacetylase inhibitor-induced responses in human periodontal ligament fibroblasts
- (2012) Tae-Il Kim et al. BIOTECHNOLOGY LETTERS
- Porphyromonas gingivalis LPS stimulation downregulates DNMT1, DNMT3a, and JMJD3 gene expression levels in human HaCaT keratinocytes
- (2012) Gláucia de Camargo Pereira et al. Clinical Oral Investigations
- Expression, polymorphism and methylation pattern of interleukin-6 in periodontal tissues
- (2012) Florença Abdanur Stefani et al. IMMUNOBIOLOGY
- Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology
- (2012) G. Hajishengallis et al. Molecular Oral Microbiology
- A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
- (2012) Laurens Kruidenier et al. NATURE
- Multigenerational epigenetic adaptation of the hepatic wound-healing response
- (2012) Müjdat Zeybel et al. NATURE MEDICINE
- Epigenetic protein families: a new frontier for drug discovery
- (2012) Cheryl H. Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Place your BETs: the therapeutic potential of bromodomains
- (2012) R.K. Prinjha et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis
- (2011) Jelena Vojinovic et al. ARTHRITIS AND RHEUMATISM
- The periodontal pathogen Porphyromonas gingivalis induces the Epstein–Barr virus lytic switch transactivator ZEBRA by histone modification
- (2011) Kenichi Imai et al. BIOCHIMIE
- Methylation pattern of IFN-γ and IL-10 genes in periodontal tissues
- (2011) Michelle Beatriz Viana et al. IMMUNOBIOLOGY
- TLR2 and TLR4 gene promoter methylation status during chronic periodontitis
- (2011) Naila Francis Paulo De Oliveira et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Periodontal ligament and gingival fibroblasts from periodontitis patients are more active in interaction with Porphyromonas gingivalis
- (2011) N. Scheres et al. JOURNAL OF PERIODONTAL RESEARCH
- Histone deacetylase inhibitors and periodontal bone loss
- (2011) M. D. Cantley et al. JOURNAL OF PERIODONTAL RESEARCH
- Interleukin-6 Gene Promoter Methylation in Rheumatoid Arthritis and Chronic Periodontitis
- (2011) Kohei Ishida et al. JOURNAL OF PERIODONTOLOGY
- Unknown
- (2011) Charles Dinarello et al. MOLECULAR MEDICINE
- Epigenetic regulation of human β-defensin 2 and CC chemokine ligand 20 expression in gingival epithelial cells in response to oral bacteria
- (2011) L Yin et al. Mucosal Immunology
- Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection
- (2010) T. Roger et al. BLOOD
- Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance
- (2010) Alessia Peserico et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Interferon-gamma promoter hypomethylation and increased expression in chronic periodontitis
- (2010) Shaoping Zhang et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Butyrate, a bacterial metabolite, induces apoptosis and autophagic cell death in gingival epithelial cells
- (2010) H. Tsuda et al. JOURNAL OF PERIODONTAL RESEARCH
- DNA Methylation Status of theIL8Gene Promoter in Aggressive Periodontitis
- (2010) Denise C. Andia et al. JOURNAL OF PERIODONTOLOGY
- Epigenetic change in e-cardherin and COX-2 to predict chronic periodontitis
- (2010) Wings TY Loo et al. Journal of Translational Medicine
- Suppression of inflammation by a synthetic histone mimic
- (2010) Edwige Nicodeme et al. NATURE
- Histone deacetylases in RA: epigenetics and epiphenomena
- (2010) Aleksander M Grabiec et al. ARTHRITIS RESEARCH & THERAPY
- Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis
- (2010) Tomoko Kawabata et al. ARTHRITIS RESEARCH & THERAPY
- An operational definition of epigenetics
- (2009) S. L. Berger et al. GENES & DEVELOPMENT
- DNA methylation status of theIL8gene promoter in oral cells of smokers and non-smokers with chronic periodontitis
- (2009) Naila F. P. Oliveira et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Alteration of PTGS2 Promoter Methylation in Chronic Periodontitis
- (2009) S. Zhang et al. JOURNAL OF DENTAL RESEARCH
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