Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems
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Title
Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems
Authors
Keywords
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Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-01-13
DOI
10.1038/s41467-020-20094-3
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Note: Only part of the references are listed.- Systematic interrogation of human promoters
- (2019) Shira Weingarten-Gabbay et al. GENOME RESEARCH
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- Deciphering eukaryotic gene-regulatory logic with 100 million random promoters
- (2019) Carl G. de Boer et al. NATURE BIOTECHNOLOGY
- Systematic Dissection of Sequence Elements Controlling σ70 Promoters Using a Genomically-Encoded Multiplexed Reporter Assay in E. coli
- (2018) Guillaume Urtecho et al. BIOCHEMISTRY
- Tuning Transcriptional Regulation through Signaling: A Predictive Theory of Allosteric Induction
- (2018) Manuel Razo-Mejia et al. Cell Systems
- Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors
- (2018) Adam J. Meyer et al. Nature Chemical Biology
- Systematic Investigation of Transcription Factor Activity in the Context of Chromatin Using Massively Parallel Binding and Expression Assays
- (2017) Michal Levo et al. MOLECULAR CELL
- Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation
- (2017) David T Riglar et al. NATURE BIOTECHNOLOGY
- Systematic dissection of genomic features determining transcription factor binding and enhancer function
- (2017) Sharon R. Grossman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Light-Controlled Cell Factories: Employing Photocaged Isopropyl-β-d-Thiogalactopyranoside for Light-Mediated Optimization oflacPromoter-Based Gene Expression and (+)-Valencene Biosynthesis in Corynebacterium glutamicum
- (2016) Dennis Binder et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay
- (2016) Ryan Tewhey et al. CELL
- Interactions between pluripotency factors specifycis-regulation in embryonic stem cells
- (2016) Chris Fiore et al. GENOME RESEARCH
- Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators
- (2016) David van Dijk et al. GENOME RESEARCH
- Using synthetic bacterial enhancers to reveal a looping-based mechanism for quenching-like repression
- (2016) Michal Brunwasser-Meirom et al. Nature Communications
- Synthetic biosensors for precise gene control and real-time monitoring of metabolites
- (2015) Jameson K. Rogers et al. NUCLEIC ACIDS RESEARCH
- Design and analysis of LacI-repressed promoters and DNA-looping in a cyanobacterium
- (2014) Daniel Camsund et al. Journal of Biological Engineering
- PEAR: a fast and accurate Illumina Paired-End reAd mergeR
- (2013) J. Zhang et al. BIOINFORMATICS
- Massively parallel synthetic promoter assays reveal the in vivo effects of binding site variants
- (2013) Ilaria Mogno et al. GENOME RESEARCH
- DNA Looping in Prokaryotes: Experimental and Theoretical Approaches
- (2013) A. Cournac et al. JOURNAL OF BACTERIOLOGY
- Generalized bacterial genome editing using mobile group II introns and Cre-lox
- (2013) P. J. Enyeart et al. Molecular Systems Biology
- Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model
- (2013) Robin P Smith et al. NATURE GENETICS
- Mechanism of promoter repression by Lac repressor-DNA loops
- (2013) N. A. Becker et al. NUCLEIC ACIDS RESEARCH
- DNA sequence-dependent mechanics and protein-assisted bending in repressor-mediated loop formation
- (2013) James Q Boedicker et al. PHYSICAL BIOLOGY
- Probing Allostery Through DNA
- (2013) S. Kim et al. SCIENCE
- Directed evolution: Past, present, and future
- (2012) Ryan E. Cobb et al. AICHE JOURNAL
- Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
- (2012) Eilon Sharon et al. NATURE BIOTECHNOLOGY
- Mechanism of promoter repression by Lac repressor–DNA loops
- (2012) Nicole A. Becker et al. NUCLEIC ACIDS RESEARCH
- Sequence dependence of transcription factor-mediated DNA looping
- (2012) Stephanie Johnson et al. NUCLEIC ACIDS RESEARCH
- RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more
- (2012) Heladia Salgado et al. NUCLEIC ACIDS RESEARCH
- Tuning Promoter Strength through RNA Polymerase Binding Site Design in Escherichia coli
- (2012) Robert C. Brewster et al. PLoS Computational Biology
- Redefining Escherichia coli σ 70 Promoter Elements: −15 Motif as a Complement of the −10 Motif
- (2011) Marko Djordjevic JOURNAL OF BACTERIOLOGY
- Predicting the strength of UP-elements and full-length E. coli σE promoters
- (2011) Virgil A. Rhodius et al. NUCLEIC ACIDS RESEARCH
- Synthetic biology: applications come of age
- (2010) Ahmad S. Khalil et al. NATURE REVIEWS GENETICS
- Gene repression by minimal lac loops in vivo
- (2010) Laura M. Bond et al. NUCLEIC ACIDS RESEARCH
- Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence
- (2010) J. B. Kinney et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dual Role of LldR in Regulation of the lldPRD Operon, Involved in L-Lactate Metabolism in Escherichia coli
- (2008) L. Aguilera et al. JOURNAL OF BACTERIOLOGY
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