Synthetic biosensors for precise gene control and real-time monitoring of metabolites

Analog synthetic biology

(2014) R. Sarpeshkar   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Adaptive Imaging Cytometry to Estimate Parameters of Gene Networks Models in Systems and Synthetic Biology

(2014) David A. Ball et al.   PLoS One

Evolution-guided optimization of biosynthetic pathways

(2014) Srivatsan Raman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The signal within the noise: efficient inference of stochastic gene regulation models using fluorescence histograms and stochastic simulations

(2013) Gabriele Lillacci et al.   BIOINFORMATICS

Screening for Enhanced Triacetic Acid Lactone Production by Recombinant Escherichia coli Expressing a Designed Triacetic Acid Lactone Reporter

(2013) Shuang-Yan Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improving d-glucaric acid production from myo-inositol in E. coli by increasing MIOX stability and myo-inositol transport

(2013) Eric Shiue et al.   METABOLIC ENGINEERING

A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli

(2013) Simone Balzer et al.   Microbial Cell Factories

Precise and reliable gene expression via standard transcription and translation initiation elements

(2013) Vivek K Mutalik et al.   NATURE METHODS

Quantitative estimation of activity and quality for collections of functional genetic elements

(2013) Vivek K Mutalik et al.   NATURE METHODS

Measurement and modeling of intrinsic transcription terminators

(2013) Guillaume Cambray et al.   NUCLEIC ACIDS RESEARCH

Composability of regulatory sequences controlling transcription and translation inEscherichia coli

(2013) Sriram Kosuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic RNA devices to expedite the evolution of metabolite-producing microbes

(2013) Jina Yang et al.   Nature Communications

A closed-loop synthetic gene circuit for the treatment of diet-induced obesity in mice

(2013) Katrin Rössger et al.   Nature Communications

Genetic Sensor for Strong Methylating Compounds

(2013) Felix Moser et al.   ACS Synthetic Biology

Benzene oxygenation and oxidation by the peroxygenase of Agrocybe aegerita

(2013) Alexander Karich et al.   AMB Express

A modular cell-based biosensor using engineered genetic logic circuits to detect and integrate multiple environmental signals

(2012) Baojun Wang et al.   BIOSENSORS & BIOELECTRONICS

Challenges in estimating percent inclusion of alternatively spliced junctions from RNA-seq data

(2012) Boyko Kakaradov et al.   BMC BIOINFORMATICS

Engineered riboswitches: Expanding researchers' toolbox with synthetic RNA regulators

(2012) Alexander Wittmann et al.   FEBS LETTERS

Lactate Utilization Is Regulated by the FadR-Type Regulator LldR in Pseudomonas aeruginosa

(2012) C. Gao et al.   JOURNAL OF BACTERIOLOGY

Genetic programs constructed from layered logic gates in single cells

(2012) Tae Seok Moon et al.   NATURE

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids

(2012) Fuzhong Zhang et al.   NATURE BIOTECHNOLOGY

Genome-scale promoter engineering by coselection MAGE

(2012) Harris H Wang et al.   NATURE METHODS

Iterative plug-and-play methodology for constructing and modifying synthetic gene networks

(2012) Kevin D Litcofsky et al.   NATURE METHODS

The Ruegeria pomeroyi acuI Gene Has a Role in DMSP Catabolism and Resembles yhdH of E. coli and Other Bacteria in Conferring Resistance to Acrylate

(2012) Jonathan D. Todd et al.   PLoS One

Transcription Factor-Based Screens and Synthetic Selections for Microbial Small-Molecule Biosynthesis

(2012) Jeffrey A. Dietrich et al.   ACS Synthetic Biology

A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level

(2012) Stephan Binder et al.   GENOME BIOLOGY

Lights on and action! Controlling microbial gene expression by light

(2011) Thomas Drepper et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Negative auto-regulation increases the input dynamic-range of the arabinose system of Escherichia coli

(2011) Daniel Madar et al.   BMC Systems Biology

Unusual Regulation of a Leaderless Operon Involved in the Catabolism of Dimethylsulfoniopropionate in Rhodobacter sphaeroides

(2011) Matthew J. Sullivan et al.   PLoS One

Design and Application of a Mevalonate-Responsive Regulatory Protein

(2010) Shuang-Yan Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-Throughput Metabolic Engineering: Advances in Small-Molecule Screening and Selection

(2010) Jeffrey A. Dietrich et al.   Annual Review of Biochemistry

Novel, Versatile, and Tightly Regulated Expression System for Escherichia coli Strains

(2010) Y. J. Choi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Design, construction and characterization of a set of insulated bacterial promoters

(2010) J. H. Davis et al.   NUCLEIC ACIDS RESEARCH

Rational design of modular circuits for gene transcription: A test of the bottom-up approach

(2010) Francesca Ceroni et al.   Journal of Biological Engineering

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression

(2009) D. Nevozhay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of Glucaric Acid from a Synthetic Pathway in Recombinant Escherichia coli

(2008) T. S. Moon et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Optimization of an E. coli L-rhamnose-inducible expression vector: test of various genetic module combinations

(2008) Angelika Wegerer et al.   BMC BIOTECHNOLOGY

Structure and functional properties of theBacillus subtilistranscriptional repressor Rex

(2008) Ellen Wang et al.   MOLECULAR MICROBIOLOGY

A synthetic Escherichia coli predator–prey ecosystem

(2008) Frederick K Balagaddé et al.   Molecular Systems Biology

Refinement and standardization of synthetic biological parts and devices

(2008) Barry Canton et al.   NATURE BIOTECHNOLOGY

A Microfluidic Device for Temporally Controlled Gene Expression and Long-Term Fluorescent Imaging in Unperturbed Dividing Yeast Cells

(2008) Gilles Charvin et al.   PLoS One