The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation
Authors
Keywords
-
Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-11-25
DOI
10.1038/s41467-020-19783-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hop depletion reduces HSF1 levels and activity and coincides with reduced stress resilience
- (2020) Abantika Chakraborty et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity
- (2019) Pablo C. Echeverria et al. PLoS One
- The ER chaperones BiP and Grp94 selectively associate when BiP is in the ADP conformation.
- (2019) Ming Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Circadian Clocks Function in Concert with Heat Shock Organizing Protein to Modulate Mutant Huntingtin Aggregation and Toxicity
- (2019) Fangke Xu et al. Cell Reports
- The Hsp70 chaperone network
- (2019) Rina Rosenzweig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co‐chaperone STI1
- (2019) Rachel E. Lackie et al. JOURNAL OF NEUROCHEMISTRY
- Proteasomes and Several Aspects of Their Heterogeneity Relevant to Cancer
- (2019) Alexey V. Morozov et al. Frontiers in Oncology
- Allosteric Modulation of Human Hsp90α Conformational Dynamics
- (2018) David L. Penkler et al. Journal of Chemical Information and Modeling
- Dancing with the Diva: Hsp90–Client Interactions
- (2018) Martina Radli et al. JOURNAL OF MOLECULAR BIOLOGY
- Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System
- (2018) Tania Morán Luengo et al. MOLECULAR CELL
- Functional and physical interaction between yeast Hsp90 and Hsp70
- (2018) Andrea N. Kravats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation induced cochaperone unfolding promotes kinase recruitment and client class-specific Hsp90 phosphorylation
- (2018) Ashleigh B. Bachman et al. Nature Communications
- Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes
- (2018) Kaushik Bhattacharya et al. Scientific Reports
- Regulation of proteasome assembly and activity in health and disease
- (2018) Adrien Rousseau et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Hsp70–Hsp90 Chaperone Cascade in Protein Folding
- (2018) Tania Morán Luengo et al. TRENDS IN CELL BIOLOGY
- Interaction of E. coli Hsp90 with DnaK Involves the DnaJ Binding Region of DnaK
- (2017) Andrea N. Kravats et al. JOURNAL OF MOLECULAR BIOLOGY
- The Plasticity of the Hsp90 Co-chaperone System
- (2017) Priyanka Sahasrabudhe et al. MOLECULAR CELL
- The ClusPro web server for protein–protein docking
- (2017) Dima Kozakov et al. Nature Protocols
- The HSP90 chaperone machinery
- (2017) Florian H. Schopf et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell
- (2017) Miklos Bagdany et al. Nature Communications
- UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome
- (2016) Roland Hjerpe et al. CELL
- Molecular Mechanism of Protein Kinase Recognition and Sorting by the Hsp90 Kinome-Specific Cochaperone Cdc37
- (2016) Dimitra Keramisanou et al. MOLECULAR CELL
- Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate
- (2016) Nuri Sung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo aspects of protein folding and quality control
- (2016) D. Balchin et al. SCIENCE
- The Biology of Proteostasis in Aging and Disease
- (2015) Johnathan Labbadia et al. Annual Review of Biochemistry
- Plasmodium falciparum Hop: Detailed analysis on complex formation with Hsp70 and Hsp90
- (2015) Rowan Hatherley et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Chaperone-mediated 26S Proteasome Remodeling Facilitates Free K63 Ubiquitin Chain Production and Aggresome Clearance
- (2015) Priyaanka Nanduri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hsp70 and Hsp90 of E. coli Directly Interact for Collaboration in Protein Remodeling
- (2015) Olivier Genest et al. JOURNAL OF MOLECULAR BIOLOGY
- Analysis of the Human Adult Urinary Metabolome Variations with Age, Body Mass Index, and Gender by Implementing a Comprehensive Workflow for Univariate and OPLS Statistical Analyses
- (2015) Etienne A. Thévenot et al. JOURNAL OF PROTEOME RESEARCH
- Hsp90: Breaking the Symmetry
- (2015) Matthias P. Mayer et al. MOLECULAR CELL
- Hsp90 regulates the dynamics of its cochaperone Sti1 and the transfer of Hsp70 between modules
- (2015) Alina Röhl et al. Nature Communications
- c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells
- (2015) Diana M. Dunn et al. Cell Reports
- Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome
- (2015) Peter Tsvetkov et al. eLife
- Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits
- (2015) Diego Acosta-Alvear et al. eLife
- Glucocorticoid Receptor Function Regulated by Coordinated Action of the Hsp90 and Hsp70 Chaperone Cycles
- (2014) Elaine Kirschke et al. CELL
- Physical Interaction between Bacterial Heat Shock Protein (Hsp) 90 and Hsp70 Chaperones Mediates Their Cooperative Action to Refold Denatured Proteins
- (2014) Hitoshi Nakamoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Variable influence on projection (VIP) for orthogonal projections to latent structures (OPLS)
- (2014) Beatriz Galindo-Prieto et al. JOURNAL OF CHEMOMETRICS
- Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ
- (2014) Jürgen Cox et al. MOLECULAR & CELLULAR PROTEOMICS
- Proteostasis impairment in protein-misfolding and -aggregation diseases
- (2014) Mark S. Hipp et al. TRENDS IN CELL BIOLOGY
- Structural characterization of the substrate transfer mechanism in Hsp70/Hsp90 folding machinery mediated by Hop
- (2014) Sara Alvira et al. Nature Communications
- A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease
- (2014) Marc Brehme et al. Cell Reports
- Regulation of proteasome activity in health and disease
- (2013) Marion Schmidt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein
- (2013) Flavio H. Beraldo et al. FASEB JOURNAL
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Dynamic Impacts of the Inhibition of the Molecular Chaperone Hsp90 on the T-Cell Proteome Have Implications for Anti-Cancer Therapy
- (2013) Ivo Fierro-Monti et al. PLoS One
- Preface to Hsp90
- (2012) Didier Picard BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
- (2012) Mikko Taipale et al. CELL
- Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?
- (2012) L. Neckers et al. CLINICAL CANCER RESEARCH
- The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop
- (2012) Andreas B Schmid et al. EMBO JOURNAL
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Increased proteasome activity in human embryonic stem cells is regulated by PSMD11
- (2012) David Vilchez et al. NATURE
- Complete subunit architecture of the proteasome regulatory particle
- (2012) Gabriel C. Lander et al. NATURE
- The Hsp90 chaperone machinery: Conformational dynamics and regulation by co-chaperones
- (2011) Jing Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation
- (2011) Surendra S. Ambegaokar et al. HUMAN MOLECULAR GENETICS
- Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment
- (2011) Jürgen Cox et al. JOURNAL OF PROTEOME RESEARCH
- Quantitative Proteomics Reveals That Hsp90 Inhibition Preferentially Targets Kinases and the DNA Damage Response
- (2011) Kirti Sharma et al. MOLECULAR & CELLULAR PROTEOMICS
- A Compound That Inhibits the HOP–Hsp90 Complex Formation and Has Unique Killing Effects in Breast Cancer Cell Lines
- (2011) Genaro Pimienta et al. MOLECULAR PHARMACEUTICS
- An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine
- (2011) Pablo C. Echeverría et al. PLoS One
- Cellular Strategies of Protein Quality Control
- (2011) B. Chen et al. Cold Spring Harbor Perspectives in Biology
- The Heat Shock Response: Life on the Verge of Death
- (2010) Klaus Richter et al. MOLECULAR CELL
- I-TASSER: a unified platform for automated protein structure and function prediction
- (2010) Ambrish Roy et al. Nature Protocols
- The 26S proteasome: assembly and function of a destructive machine
- (2010) Nerea Gallastegui et al. TRENDS IN BIOCHEMICAL SCIENCES
- Integration of Clearance Mechanisms: The Proteasome and Autophagy
- (2010) E. Wong et al. Cold Spring Harbor Perspectives in Biology
- Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility
- (2009) Pablo C. Echeverria et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- C. elegans STI-1, the Homolog of Sti1/Hop, Is Involved in Aging and Stress Response
- (2009) Hyun-Ok Song et al. JOURNAL OF MOLECULAR BIOLOGY
- Chaperone-mediated pathway of proteasome regulatory particle assembly
- (2009) Jeroen Roelofs et al. NATURE
- Molecular mechanisms of proteasome assembly
- (2009) Shigeo Murata et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A Novel Class of Small Molecule Inhibitors of Hsp90
- (2008) Fang Yi et al. ACS Chemical Biology
- Hsp90-mediated Assembly of the 26 S Proteasome Is Involved in Major Histocompatibility Complex Class I Antigen Processing
- (2008) Taketoshi Yamano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
- Characterization of the proteasome interaction network using a QTAX-based tag-team strategy and protein interaction network analysis
- (2008) C. Guerrero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now