Rhodium catalysts derived from a fluorinated phanephos ligand are highly active catalysts for direct asymmetric reductive amination of secondary amines

Enantioselective Hydrogenation of Activated Aryl Imines Catalyzed by an Iron(II) P-NH-P′ Complex

(2019) Chris S. G. Seo et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of Chiral Primary Amines by Ruthenium-Catalyzed Direct Reductive Amination of Alkyl Aryl Ketones with Ammonium Salts and Molecular H2

(2018) Xuefeng Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst

(2018) Ernest Salomó et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of a Key Intermediate for Tofacitinib via a Dynamic Kinetic Resolution-Reductive Amination Protocol

(2018) Gerard K. M. Verzijl et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Direct Asymmetric Ruthenium-Catalyzed Reductive Amination of Alkyl–Aryl Ketones with Ammonia and Hydrogen

(2017) Joan Gallardo-Donaire et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium-catalyzed asymmetric hydrogenation of cyclic iminium salts

(2017) Yue Ji et al.   Organic Chemistry Frontiers

Mechanistic investigation of a Ru-catalyzed direct asymmetric reductive amination reaction for a batch or continuous process scale-up: an industrial perspective

(2017) Shujauddin M. Changi et al.   Reaction Chemistry & Engineering

Remarkable co-catalyst effects on the enantioselective hydrogenation of unfunctionalised enamines: both enantiomers of product from the same enantiomer of catalyst

(2016) Sergey Tin et al.   Catalysis Science & Technology

Hydrogenation of unactivated enamines to tertiary amines: rhodium complexes of fluorinated phosphines give marked improvements in catalytic activity

(2015) Sergey Tin et al.   Beilstein Journal of Organic Chemistry

An (R)-Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines

(2015) Shahed Hussain et al.   ChemCatChem

Highly Regio- and Enantioselective Synthesis of γ,δ-Unsaturated Amido Esters by Catalytic Hydrogenation of Conjugated Enamides

(2014) Min Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Hydrogenation ofN-Aryl Imines Derived from Acetophenones by Using Ru-Pybox Complexes under Hydrogenation or Transfer Hydrogenation Conditions in Isopropanol

(2014) Estefanía Menéndez-Pedregal et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent achievements in developing the biocatalytic toolbox for chiral amine synthesis

(2014) Hannes Kohls et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Simultaneous control of regioselectivity and enantioselectivity in the hydroxycarbonylation and methoxycarbonylation of vinyl arenes

(2013) Tina M. Konrad et al.   CHEMICAL COMMUNICATIONS

Biocatalytic Approaches to the Synthesis of Enantiomerically Pure Chiral Amines

(2013) Diego Ghislieri et al.   TOPICS IN CATALYSIS

Rhodium-catalysed asymmetric hydrogenation as a valuable synthetic tool for the preparation of chiral drugs

(2012) Pablo Etayo et al.   CHEMICAL SOCIETY REVIEWS

Planar Chiral Phosphines Derived from [2.2]Paracyclophane

(2012) Gareth J. Rowlands   ISRAEL JOURNAL OF CHEMISTRY

Sitagliptin Manufacture: A Compelling Tale of Green Chemistry, Process Intensification, and Industrial Asymmetric Catalysis

(2011) Aman A. Desai   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Transition-Metal and Chiral Brønsted Acid Catalysis: Enantioselective Hydrogenation of Imines To Form Amines

(2011) Shaolin Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

On the rate-determining step and the ligand electronic effects in rhodium catalysed hydrogenation of enamines and the hydroaminomethylation of alkenes

(2011) José A. Fuentes et al.   Catalysis Science & Technology

Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

(2010) Thomas C. Nugent et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Hydrogenation of Unfunctionalized Enamines Catalyzed by Iridium Complexes of Chiral Spiro N,N-Diarylphosphoramidites

(2010) Pucha Yan et al.   CHINESE JOURNAL OF CHEMISTRY

Enantioselective Synthesis of Chiral Tetrahydroisoquinolines by Iridium-Catalyzed Asymmetric Hydrogenation of Enamines

(2009) Pu-Cha Yan et al.   ADVANCED SYNTHESIS & CATALYSIS

Biocatalytic Routes to Optically Active Amines

(2009) Matthias Höhne et al.   ChemCatChem

Iridium-Catalyzed Asymmetric Hydrogenation of Cyclic Enamines

(2009) Guo-Hua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Asymmetric Reductive Amination

(2009) Dietrich Steinhuebel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal−Brønsted Acid Cooperative Catalysis for Asymmetric Reductive Amination

(2009) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Efficient Asymmetric Synthesis of Taranabant, a CB1R Inverse Agonist for the Treatment of Obesity

(2009) Debra J. Wallace et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Highly enantioselective Ir-catalyzed hydrogenation of exocyclic enamines

(2009) Xiao-Bing Wang et al.   TETRAHEDRON-ASYMMETRY

Chiral Counteranion-Aided Asymmetric Hydrogenation of Acyclic Imines

(2008) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enamines: efficient nucleophiles for the palladium-catalyzed asymmetric allylic alkylation

(2008) Xiaohu Zhao et al.   TETRAHEDRON

Efficient, enantioselective synthesis of a β,β-disubstituted carboxylic acid by Ru-XylPhanePhos-catalyzed asymmetric hydrogenation

(2008) Gabriela A. Grasa et al.   TETRAHEDRON LETTERS

Access to chiral tertiary amines via the iridium-catalyzed asymmetric hydrogenation of enamines

(2008) Pradeep Cheruku et al.   TETRAHEDRON LETTERS