Gut microbiota in dementia. Critical review of novel findings and their potential application

Concomitant memantine and Lactobacillus plantarum treatment attenuates cognitive impairments in APP/PS1 mice

(2020) Qiu-Jun Wang et al.   Aging-US

Relationship between dementia and gut microbiome-associated metabolites: a cross-sectional study in Japan

(2020) Naoki Saji et al.   Scientific Reports

Pro - and anti-inflammatory cytokines in the CSF of Alzheimer´s disease patients and their correlation with cognitive decline

(2019) R. Taipa et al.   NEUROBIOLOGY OF AGING

Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue

(2019) Baoguo Li et al.   Cell Reports

Efficacy and Safety of Lactobacillus Plantarum C29-Fermented Soybean (DW2009) in Individuals with Mild Cognitive Impairment: A 12-Week, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

(2019) Yun-Ha Hwang et al.   Nutrients

Psychobiotics in mental health, neurodegenerative and neurodevelopmental disorders

(2019) Li-Hao Cheng et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Neuroinflammation in mild cognitive impairment and Alzheimer’s disease: A meta-analysis

(2019) Steven Bradburn et al.   AGEING RESEARCH REVIEWS

Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort

(2019) Ping Liu et al.   BRAIN BEHAVIOR AND IMMUNITY

Alzheimer's disease and symbiotic microbiota: an evolutionary medicine perspective

(2019) Molly Fox et al.   Annals of the New York Academy of Sciences

Time to test antibacterial therapy in Alzheimer’s disease

(2019) Francesco Panza et al.   BRAIN

Microbiome Influence in the Pathogenesis of Prion and Alzheimer’s Diseases

(2019) Valeria D’Argenio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Higher Circulating Trimethylamine N-oxide Sensitizes Sevoflurane-Induced Cognitive Dysfunction in Aged Rats Probably by Downregulating Hippocampal Methionine Sulfoxide Reductase A

(2019) Liang Zhao et al.   NEUROCHEMICAL RESEARCH

Fecal microbiota transplantation alleviated Alzheimer’s disease-like pathogenesis in APP/PS1 transgenic mice

(2019) Jing Sun et al.   Translational Psychiatry

Brain Insulin Resistance and Hippocampal Plasticity: Mechanisms and Biomarkers of Cognitive Decline

(2019) Matteo Spinelli et al.   Frontiers in Neuroscience

C‐type lectin‐like receptor 2 and zonulin are associated with mild cognitive impairment and Alzheimer's disease

(2019) Xin Wang et al.   ACTA NEUROLOGICA SCANDINAVICA

Discovery of Gut Bacteria Specific to Alzheimer’s Associated Diseases is a Clue to Understanding Disease Etiology: Meta-Analysis of Population-Based Data on Human Gut Metagenomics and Metabolomics

(2019) Elena L. Paley   JOURNAL OF ALZHEIMERS DISEASE

The microbiota regulate neuronal function and fear extinction learning

(2019) Coco Chu et al.   NATURE

Calorie restriction slows age-related microbiota changes in an Alzheimer’s disease model in female mice

(2019) Laura M. Cox et al.   Scientific Reports

Facilitation of Gastrointestinal (GI) Tract Microbiome-Derived Lipopolysaccharide (LPS) Entry Into Human Neurons by Amyloid Beta-42 (Aβ42) Peptide

(2019) Walter J. Lukiw et al.   Frontiers in Cellular Neuroscience

Helicobacter pylori seropositivity and its association with incident all-cause and Alzheimer's disease dementia in large national surveys

(2018) May A. Beydoun et al.   Alzheimers & Dementia

Lactobacilli and bifidobacteria ameliorate memory and learning deficits and oxidative stress in β-amyloid (1–42) injected rats

(2018) Somayeh Athari Nik Azm et al.   Applied Physiology Nutrition and Metabolism

Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States

(2018) Mark P. Mattson et al.   Cell Metabolism

Impact of gut microbiota on neurological diseases: Diet composition and novel treatments

(2018) Ana Larroya-García et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Alzheimer’s Disease, Oligomers, and Inflammation

(2018) Gianluigi Forloni et al.   JOURNAL OF ALZHEIMERS DISEASE

Shifts in gut microbiota composition in an APP/PSS1 transgenic mouse model of Alzheimer's disease during lifespan

(2018) C. Bäuerl et al.   LETTERS IN APPLIED MICROBIOLOGY

Whole-Body Cryotherapy Decreases the Levels of Inflammatory, Oxidative Stress, and Atherosclerosis Plaque Markers in Male Patients with Active-Phase Ankylosing Spondylitis in the Absence of Classical Cardiovascular Risk Factors

(2018) Agata Stanek et al.   MEDIATORS OF INFLAMMATION

The Gut Microbiome Alterations and Inflammation-Driven Pathogenesis of Alzheimer’s Disease—a Critical Review

(2018) Marta Sochocka et al.   MOLECULAR NEUROBIOLOGY

Neuroinflammation, Gut Microbiome, and Alzheimer’s Disease

(2018) Li Lin et al.   MOLECULAR NEUROBIOLOGY

Intestinal Bacterial Flora and Alzheimer’s Disease

(2018) M. Bostanciklioğlu   NEUROPHYSIOLOGY

Decreased Oxidative Stress in Male Patients with Active Phase Ankylosing Spondylitis Who Underwent Whole-Body Cryotherapy in Closed Cryochamber

(2018) Agata Stanek et al.   Oxidative Medicine and Cellular Longevity

Probiotic Supplementation in Patients with Alzheimer’s Dementia – An Explorative Intervention Study

(2018) Friedrich Leblhuber et al.   Current Alzheimer Research

Gut microbiota, dietary intakes and intestinal permeability reflected by serum zonulin in women

(2018) S. Mörkl et al.   EUROPEAN JOURNAL OF NUTRITION

Conversion of Mild Cognitive Impairment to Dementia among Subjects with Diabetes: A Population-Based Study of Incidence and Risk Factors with Five Years of Follow-up

(2018) Fei Ma et al.   JOURNAL OF ALZHEIMERS DISEASE

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome

(2018) Siamak MahmoudianDehkordi et al.   Alzheimers & Dementia

The Possibility of an Infectious Etiology of Alzheimer Disease

(2018) Ghulam M. Ashraf et al.   MOLECULAR NEUROBIOLOGY

Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer’s Disease

(2018) Mikael Marttinen et al.   Frontiers in Neuroscience

Intraneuronal protein aggregation as a trigger for inflammation and neurodegeneration in the aging brain

(2017) Antonio Currais et al.   FASEB JOURNAL

Whole-body Cryotherapy as a Recovery Technique after Exercise: A Review of the Literature

(2017) Catriona Rose et al.   INTERNATIONAL JOURNAL OF SPORTS MEDICINE

The Gut Microbiota and Alzheimer’s Disease

(2017) Chunmei Jiang et al.   JOURNAL OF ALZHEIMERS DISEASE

CNS inflammation and neurodegeneration

(2017) Tanuja Chitnis et al.   JOURNAL OF CLINICAL INVESTIGATION

Lactobacilli-fermented cow's milk attenuated lipopolysaccharide-induced neuroinflammation and memory impairment in vitro and in vivo

(2017) Nurul Huda Musa et al.   JOURNAL OF DAIRY RESEARCH

Late-life body mass index, rapid weight loss, apolipoprotein E ε4 and the risk of cognitive decline and incident dementia

(2017) S. P. Bell et al.   Journal of Nutrition Health & Aging

Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis

(2017) Anna Worthmann et al.   NATURE MEDICINE

Natural polyreactive IgA antibodies coat the intestinal microbiota

(2017) Jeffrey J. Bunker et al.   SCIENCE

Role of neuroinflammation in neurodegeneration: new insights

(2017) Róisín M. McManus et al.   Alzheimers Research & Therapy

The role of microbial amyloid in neurodegeneration

(2017) Robert P. Friedland et al.   PLoS Pathogens

Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway

(2017) Ming‐liang Chen et al.   Journal of the American Heart Association

Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism

(2017) Rina Komazaki et al.   Scientific Reports

Neuroinflammation in Alzheimer's disease: Current evidence and future directions

(2016) Valeria Calsolaro et al.   Alzheimers & Dementia

GABA production and structure of gadB / gadC genes in Lactobacillus and Bifidobacterium strains from human microbiota

(2016) R.A. Yunes et al.   ANAEROBE

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

Gut Microbial Metabolites Fuel Host Antibody Responses

(2016) Myunghoo Kim et al.   Cell Host & Microbe

Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure

(2016) Marika Ziętak et al.   Cell Metabolism

Microbes and the mind: emerging hallmarks of the gut microbiota-brain axis

(2016) Kylynda C. Bauer et al.   CELLULAR MICROBIOLOGY

Whole- and partial-body cryostimulation/cryotherapy: Current technologies and practical applications

(2016) Romain Bouzigon et al.   JOURNAL OF THERMAL BIOLOGY

Signals from the gut microbiota to distant organs in physiology and disease

(2016) Bjoern O Schroeder et al.   NATURE MEDICINE

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

(2016) Harm J. van de Haar et al.   RADIOLOGY

Whole-Body Cryostimulation as an Effective Method of Reducing Oxidative Stress in Healthy Men

(2016) Agata Stanek et al.   Advances in Clinical and Experimental Medicine

Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial

(2016) Elmira Akbari et al.   Frontiers in Aging Neuroscience

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Modifiable Predictors of Dementia in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis

(2015) Claudia Cooper et al.   AMERICAN JOURNAL OF PSYCHIATRY

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

(2015) S.M. O’Mahony et al.   BEHAVIOURAL BRAIN RESEARCH

A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat

(2015) Rong Xu et al.   BMC GENOMICS

Gut Microbiota Orchestrates Energy Homeostasis during Cold

(2015) Claire Chevalier et al.   CELL

Gut Microbiota Interacts With Brain Microstructure and Function

(2015) José-Manuel Fernandez-Real et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Elevated fecal calprotectin in patients with Alzheimer’s dementia indicates leaky gut

(2015) Friedrich Leblhuber et al.   JOURNAL OF NEURAL TRANSMISSION

Collective unconscious: How gut microbes shape human behavior

(2015) Timothy G. Dinan et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Enhancing Rehabilitative Therapies with Vagus Nerve Stimulation

(2015) Seth A. Hays   Neurotherapeutics

Repositioning of Memantine as a Potential Novel Therapeutic Agent against Meningitic E. coli–Induced Pathogenicities through Disease-Associated Alpha7 Cholinergic Pathway and RNA Sequencing-Based Transcriptome Analysis of Host Inflammatory Responses

(2015) Jing-Yi Yu et al.   PLoS One

Body mass index and mild cognitive impairment-to-dementia progression in 24 months: a prospective study

(2014) T Sobów et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

(2014) Xiang Gao et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Correction: Time-Course of Changes in Inflammatory Response after Whole-Body Cryotherapy Multi Exposures following Severe Exercise

(2014) Hervé Pournot et al.   PLoS One

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

The role of pro-inflammatory S100A9 in Alzheimer’s disease amyloid-neuroinflammatory cascade

(2013) Chao Wang et al.   ACTA NEUROPATHOLOGICA

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

(2013) Brian J. Bennett et al.   Cell Metabolism

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Impaired glycemia increases disease progression in mild cognitive impairment

(2013) Jill K. Morris et al.   NEUROBIOLOGY OF AGING

Probiotics treatment improves diabetes-induced impairment of synaptic activity and cognitive function: Behavioral and electrophysiological proofs for microbiome–gut–brain axis

(2013) S. Davari et al.   NEUROSCIENCE

Contrasting effects of Bifidobacterium breve NCIMB 702258 and Bifidobacterium breve DPC 6330 on the composition of murine brain fatty acids and gut microbiota

(2012) Rebecca Wall et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Prolonged elevation in hippocampal Aβ and cognitive deficits following repeated endotoxin exposure in the mouse

(2012) Marielle S. Kahn et al.   BEHAVIOURAL BRAIN RESEARCH

Resveratrol Attenuates Obesity-Associated Peripheral and Central Inflammation and Improves Memory Deficit in Mice Fed a High-Fat Diet

(2012) B. T. Jeon et al.   DIABETES

γ-Aminobutyric acid production by culturable bacteria from the human intestine

(2012) E. Barrett et al.   JOURNAL OF APPLIED MICROBIOLOGY

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies

(2011) K. J. Anstey et al.   Obesity Reviews

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of prolonged whole-body cryostimulation treatment with different amounts of sessions on chosen pro- and anti-inflammatory cytokines levels in healthy men

(2011) Anna Lubkowska et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Body Mass Index and Cognitive Decline in Mild Cognitive Impairment

(2010) Benjamin B. Cronk et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Accelerated Progression From Mild Cognitive Impairment to Dementia in People With Diabetes

(2010) W. Xu et al.   DIABETES

HPA axis responsiveness to stress: Implications for healthy aging

(2010) Greti Aguilera   EXPERIMENTAL GERONTOLOGY

Bacterial infection causes stress-induced memory dysfunction in mice

(2010) M. G. Gareau et al.   GUT

Increased Serum IL-1β Level in Alzheimer’s Disease and Mild Cognitive Impairment

(2009) Orestes Vicente Forlenza et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES