Repositioning of Memantine as a Potential Novel Therapeutic Agent against Meningitic E. coli–Induced Pathogenicities through Disease-Associated Alpha7 Cholinergic Pathway and RNA Sequencing-Based Transcriptome Analysis of Host Inflammatory Responses

Title
Repositioning of Memantine as a Potential Novel Therapeutic Agent against Meningitic E. coli–Induced Pathogenicities through Disease-Associated Alpha7 Cholinergic Pathway and RNA Sequencing-Based Transcriptome Analysis of Host Inflammatory Responses
Authors
Keywords
Meningitis, Bacteremia, Nicotinic acetylcholine receptors, Escherichia coli infections, Intracellular pathogens, Bacterial meningitis, Mouse models, Drug therapy
Journal
PLoS One
Volume 10, Issue 5, Pages e0121911
Publisher
Public Library of Science (PLoS)
Online
2015-05-20
DOI
10.1371/journal.pone.0121911

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