Repositioning of Memantine as a Potential Novel Therapeutic Agent against Meningitic E. coli–Induced Pathogenicities through Disease-Associated Alpha7 Cholinergic Pathway and RNA Sequencing-Based Transcriptome Analysis of Host Inflammatory Responses
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Repositioning of Memantine as a Potential Novel Therapeutic Agent against Meningitic E. coli–Induced Pathogenicities through Disease-Associated Alpha7 Cholinergic Pathway and RNA Sequencing-Based Transcriptome Analysis of Host Inflammatory Responses
Authors
Keywords
Meningitis, Bacteremia, Nicotinic acetylcholine receptors, Escherichia coli infections, Intracellular pathogens, Bacterial meningitis, Mouse models, Drug therapy
Journal
PLoS One
Volume 10, Issue 5, Pages e0121911
Publisher
Public Library of Science (PLoS)
Online
2015-05-20
DOI
10.1371/journal.pone.0121911
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Endotoxaemia resulting from decreased serotonin tranporter (5-HTT) function: A reciprocal risk factor for depression and insulin resistance?
- (2015) Igor A. Pomytkin et al. BEHAVIOURAL BRAIN RESEARCH
- Early-Onset Neonatal Sepsis
- (2014) K. A. Simonsen et al. CLINICAL MICROBIOLOGY REVIEWS
- Memantine delayed N-methyl-D-aspartate -induced convulsions in neonatal rats
- (2014) Ashish Dhir et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014
- (2014) L. S. Schneider et al. JOURNAL OF INTERNAL MEDICINE
- Mfsd2a is critical for the formation and function of the blood–brain barrier
- (2014) Ayal Ben-Zvi et al. NATURE
- Neurological Complications after Neonatal Bacteremia: The Clinical Characteristics, Risk Factors, and Outcomes
- (2014) Shih-Ming Chu et al. PLoS One
- mRNA-Binding Protein ZFP36 Is Expressed in Atherosclerotic Lesions and Reduces Inflammation in Aortic Endothelial Cells
- (2013) Huanchun Zhang et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Delivery of host cell-directed therapeutics for intracellular pathogen clearance
- (2013) Michael A Collier et al. Expert Review of Anti-Infective Therapy
- proMetalloproteinase-10 is associated with brain damage and clinical outcome in acute ischemic stroke
- (2013) J. A. Rodríguez et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Circulating Brain Microvascular Endothelial Cells (cBMECs) as Potential Biomarkers of the Blood–Brain Barrier Disorders Caused by Microbial and Non-Microbial Factors
- (2013) Sheng-He Huang et al. PLoS One
- Associations between Genetic Polymorphisms in IL-33, IL1R1 and Risk for Inflammatory Bowel Disease
- (2013) Anna Latiano et al. PLoS One
- High Throughput Gene Expression Analysis Identifies Reliable Expression Markers of Human Corneal Endothelial Cells
- (2013) Zhenzhi Chng et al. PLoS One
- Interferon and Ribavirin Combination Treatment Synergistically Inhibit HCV Internal Ribosome Entry Site Mediated Translation at the Level of Polyribosome Formation
- (2013) Rajesh Panigrahi et al. PLoS One
- α7nAchR/NMDAR coupling affects NMDAR function and object recognition
- (2013) Shupeng Li et al. Molecular Brain
- Peripheral blood RNA gene expression profiling in patients with bacterial meningitis
- (2013) Margit Lill et al. Frontiers in Neuroscience
- Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome
- (2012) Zhiyu Peng et al. NATURE BIOTECHNOLOGY
- Vimentin and PSF Act in Concert to Regulate IbeA+ E. coli K1 Induced Activation and Nuclear Translocation of NF-κB in Human Brain Endothelial Cells
- (2012) Feng Chi et al. PLoS One
- A20 (TNFAIP3) Alleviates CVB3-Induced Myocarditis via Inhibiting NF-κB Signaling
- (2012) Jun Gui et al. PLoS One
- Recruitment of α7 nicotinic acetylcholine receptor to caveolin-1-enriched lipid rafts is required for nicotine-enhancedEscherichia coliK1 entry into brain endothelial cells
- (2011) Feng Chi et al. Future Microbiology
- Differential expression in RNA-seq: A matter of depth
- (2011) S. Tarazona et al. GENOME RESEARCH
- The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain
- (2011) Simon M. Manning et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Meningitic Escherichia coli K1 Penetration and Neutrophil Transmigration Across the Blood–Brain Barrier are Modulated by Alpha7 Nicotinic Receptor
- (2011) Feng Chi et al. PLoS One
- Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis
- (2011) Tej K. Pareek et al. Scientific Reports
- TargetingN-methyl-D-aspartate receptors for treatment of neuropathic pain
- (2011) Hong-Yi Zhou et al. Expert Review of Clinical Pharmacology
- Involvement of IbeA in Meningitic Escherichia coli K1-Induced Polymorphonuclear Leukocyte Transmigration Across Brain Endothelial Cells
- (2010) Xiaojuan Che et al. BRAIN PATHOLOGY
- Risk factors of mortality in septic newborns in neonatal intensive care units (NICUs) in Tbilisi, the Republic of Georgia
- (2009) Maia Butsashvili et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Review: Pathophysiology and treatment of bacterial meningitis
- (2009) Olaf Hoffman et al. Therapeutic Advances in Neurological Disorders
- Gene expression analysis of BCR/ABL1-dependent transcriptional response reveals enrichment for genes involved in negative feedback regulation
- (2008) Petra Håkansson et al. GENES CHROMOSOMES & CANCER
- Prolongation of Hospital Stay and Additional Costs Due to Nosocomial Bloodstream Infection in an Algerian Neonatal Care Unit
- (2008) Mohamed Lamine Atif et al. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
- Focal Point Theory Models for Dissecting Dynamic Duality Problems of Microbial Infections
- (2008) S.-H. Huang et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Mapping and quantifying mammalian transcriptomes by RNA-Seq
- (2008) Ali Mortazavi et al. NATURE METHODS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started